XLOC_035535 (ercc8)


Basic Information

Item Value
gene id XLOC_035535
gene name ercc8
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 16738282 ~ 16757285 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00069695
GCTGCTTTCTACACAACAAAGTGCACAACAATCATTTGTAAAAACTGAAATAGAGCTTATACGTTTAGTGTGTTGTGCAGGATgaatttgtttagtttaaaaacgcgGTTTTACGGGCTGAACAGTCACCACTTAAATGTTTGGGTTAAAGGCTGTAAACAGACCTCTGCTACAGTTATTTCACTCTGACGAGAGTCATCAACATACACATGAATAAACGAAACACAAGTCCAATGTCTCTAAAACAATGTTAAGTTTTCTTTACGCAAGGCAAACTGGGCTTGACGACCCAGTTCGACTGAGACGTGCAGAATCCACACGCAGGGTGCTGAGTCTTGAGTTGAACCACAACAGGGATGTGGATCGTATTCATGGCAATGGAATCAACACCCTTGACATTGAGGTTATTGATGGAAGATATATGCTGTCAGGCGGATCTGATGGCGTAATTGTGATTTATGACTTAGAGAACAACAGCAAGAAGCCTCAATACACCTGCAAAGCAATCTGCACTGTGGGCAGGTCCAGTCGACATGTGCATAAATTCAGCGTGGAAACAGTGCAGTGGTACCCACATGACACCGGTATGTTTGTATCCAGCTCTTTCGACAAAACCATGAAAGTCTGGGATGCTGAAACTCTGAAGCCAGCTGATGAGTTCCAGTTTGATGGCAATGTCTACTGTCATCACATGTCTCCTATAGCCCGGAAGCACAGCCTTGTGGCAGCTCTATTGTGCTCTGTGTTGGCAGTTGGTACCAAAGACCCCAAAGTGCAGCTTTG
>TCONS_00069696
AAAAACTGAAATAGAGCTTATACGTTTAGTGTGTTGTGCAGGATgaatttgtttagtttaaaaacgcgGTTTTACGGGCTGAACAGTCACCACTTAAATGTTTGGGTTAAAGGCTGTAAACAGACCTCTGCTACAGTTATTTCACTCTGACGAGAGTCATCAACATACACATGAATAAACGAAACACAAGTCCAATGTCTCTAAAACAATGTTAAGTTTTCTTTACGCAAGGCAAACTGGGCTTGACGACCCAGTTCGACTGAGACGTGCAGAATCCACACGCAGGGTGCTGAGTCTTGAGTTGAACCACAACAGGGATGTGGATCGTATTCATGGCAATGGAATCAACACCCTTGACATTGAGGTTATTGATGGAAGATATATGCTGTCAGGCGGATCTGATGGCGTAATTGTGATTTATGACTTAGAGAACAACAGCAAGAAGCCTCAATACACCTGCAAAGCAATCTGCACTGTGGGCAGGTCCAGTCGACATGTGCATAAATTCAGCGTGGAAACAGTGCAGTGGTACCCACATGACACCGGTATGTTTGTATCCAGCTCTTTCGACAAAACCATGAAAGTCTGGGATGCTGAAACTCTGAAGCCAGCTGATGAGTTCCAGTTTGATGGCAATGTCTACTGTCATCACATGTCTCCTATAGCCCGGAAGCACAGCCTTGTGGCAGTTGGTACCAAAGACCCCAAAGTGCAGCTTTGTGATCTGAAGTCTGGGTCGCGTATCCACATCCTTCAGGGTCACAGGGGCGAGATCCTCTCAGTGAAATGGTCTCCACGATATGAACACATACTGGCCACTGCCAGCACTGACAGTAGGGTTCGCATCTGGGATGTGAGAAGAGCCTCCGGGAGTCTTTTTACTTTGGACCAGCACAATGGAGATAAATCCAAGGCCTCGTCTGAAGCAGTGAACACAGCACACAACGGAAGAGTGAATGGGTTGTGTTTCACAGCTGATGGACTCCACCTCCTCACTACAGGGACAGATGATCGCATGCGTCTGTGGAATAGCGGCACTGGGGAAAACACATTAGTGAACTATGGGAAGGTCGTGAACGAGAGCCGCAAAGGTCTGAAGTTTACCGTATCAAGGGGTTGCAGTCCAGAGTTTGTGTTTGTGCCATGTGGAAGCTCAGTAGCGGTGTATGGGCTTCATTCTGGAGAGCTGATCACTATGTTAAGGGGACATTATAATAATGTGGACTGCTGCGAGTTCCACCCTGATTATCAGGAGCTGTACAGTGGAGGTAAAGACTGTAACATACTTGCCTGGGTTCCAGTGTTAAGACAGCCTGATGTTGATGATGAAGAAACCAACACGAAACGGGGTGGAACGCAAGCTGCTATCAATCCTGCTTTTGCCGATGCCTGGAGCAGCGACGAAGACTGACAGATCAACCCAGGAATGTTtttttatatccaaatacaccaCTTTATACATTATTAAAGAAGTCAAAGTGCTCTTATTGCATTCAGAGGCACAGCAGGTGCATATAAGCTCAATGTACAGAAAAAAAGACTTGTGGGAGATTTGTTCTCATTGCTTGTGACCATCTGATTTGCATGTGGATTAAAGTTTTACATCATCTTGTGATTCACTTGTACATTTACTTTTCACCTAGATAGGAACAATTGATCAGTGGTTTAGTGTAAAAACTATGCTGATGATTAtgcaaaatgtttgtttataaattGTGGCATGATCATTGAAGAGTTTTAAATATGTTCTTCTGAATATTGTAGATAAATGTTGACAGAATCACTTTGAGGATGAAATTTATGCTACAAATATTGTTGTCAGTTTTTTATAGGATAAAATAaaggaacttttttttatataaa
>TCONS_00069697
GTGGCTCCTCTGTGTTGCCAAACGCCACTTATCTACTGACCCTGAGTCTGGTATTTGCATTGTAACTGACACACAGGAATGGTGTCTAAGCAACATTCATTACCTTTTTATTGCCCCCTTAAAGCACATCTAAcatgtatatttgtgtattttctgatttttctttatttgacATTAGATTCAGGTGTTATTCcgttagaaatataaaataaaagtgtacaaaaataaataaatgtagtagtatttattaatttgtttgttttctcaGCCAGCTGATGAGTTCCAGTTTGATGGCAATGTCTACTGTCATCACATGTCTCCTATAGCCCGGAAGCACAGCCTTGTGGCAGTTGGTACCAAAGACCCCAAAGTGCAGCTTTGTGATCTGAAGTCTGGGTCGCGTATCCACATCCTTCAGGGTCACAGGGGCGAGATCCTCTCAGTGAAATGGTCTCCACGATATGAACACATACTGGCCACTGCCAGCACTGACAGTAGGGTTCGCATCTGGGATGTGAGAAGAGCCTCCGGGAGTCTTTTTACTTTGGACCAGCACAATGGAGATAAATCCAAGGCCTCGTCTGAAGCAGTGAACACAGCACACAACGGAAGAGTGAATGGGTTGTGTTTCACAGCTGATGGACTCCACCTCCTCACTACAGGGACAGATGATCGCATGCGTCTGTGGAATAGCGGCACTGGGGAAAACACATTAGTGAACTATGGGAAGGTCGTGAACGAGAGCCGCAAAGGTCTGAAGTTTACCGTATCAAGGGGTTGCAGTCCAGAGTTTGTGTTTGTGCCATGTGGAAGCTCAGTAGCGGTGTATGGGCTTCATTCTGGAGAGCTGATCACTATGTTAAGGGGACATTATAATAATGTGGACTGCTGCGAGTTCCACCCTGATTATCAGGAGCTGTACAGTGGAGGTAAAGACTGTAACATACTTGCCTGGGTTCCAGTGTTAAGACAGCCTGATGTTGATGATGA
>TCONS_00069698
CAATGTCTACTGTCATCACATGTCTCCTATAGCCCGGAAGCACAGCCTTGTGGCAGTTGGTACCAAAGACCCCAAAGTGCAGCTTTGTGATCTGAAGTCTGGGTCGCGTATCCACATCCTTCAGGGTGAGTAATGCCTGTTGTTTCTGAATGGAGACAGCCCTGGTGGGGGGGATAATGTactctttttaaaaaacaaaagcttgAATGTTTTAAGCATGAGTTATTGAATCCTGGCTATTTTGCCACCTGACCTTCTCAGATGCCACAGTGTATGATGGATCATTAGTACGTATGCTTAAATGTATTACAGTTTCTGCGATTGCAATATCTGAATTGTCAGCAGTCTTTGGTTTTACATGATtgttcagaaatcattctaaaagGCTGATTTGCTGCTCAGGAAATATTATCAGGGCTGCTGAGTATTATTAAGCA

Function

symbol description
ercc8 Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within response to UV. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and nucleotide-excision repair complex. Human ortholog(s) of this gene implicated in Cockayne syndrome; Cockayne syndrome A; and UV-sensitive syndrome. Orthologous to human ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit).

GO:

id name namespace
GO:0045739 positive regulation of DNA repair biological_process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0006283 transcription-coupled nucleotide-excision repair biological_process
GO:0000109 nucleotide-excision repair complex cellular_component
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex cellular_component
GO:0004842 ubiquitin-protein transferase activity molecular_function

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko03420 Nucleotide excision repair
ko04121 Ubiquitin system
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-041010-60 Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within response to UV. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and nucleotide-excision repair complex. Human ortholog(s) of this gene implicated in Cockayne syndrome; Cockayne syndrome A; and UV-sensitive syndrome. Orthologous to human ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit).

Ensembl:

ensembl_id ENSDARG00000069283

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00069695 False 783 mRNA 0.44 6 16738282 16748516
TCONS_00069696 False 1863 mRNA 0.43 12 16738321 16757285
TCONS_00069697 False 990 lncRNA 0.45 7 16744062 16755717
TCONS_00069698 True 437 lncRNA 0.42 2 16744356 16748866

Neighbor

gene id symbol gene type direction distance location
XLOC_035534 smim15 coding upstream 7914 16726386 ~ 16730368 (+)
XLOC_035533 NA coding upstream 16906 16719107 ~ 16721376 (+)
XLOC_035532 si:ch211-198n5.11 coding upstream 49771 16676894 ~ 16688511 (+)
XLOC_035531 NA coding upstream 124811 16609678 ~ 16613471 (+)
XLOC_035529 NA coding upstream 156240 16563953 ~ 16582042 (+)
XLOC_035536 elovl7a coding downstream 1019 16758304 ~ 16769798 (+)
XLOC_035537 CR925863.1 coding downstream 14889 16772174 ~ 16810253 (+)
XLOC_035538 pde4d coding downstream 232835 16990120 ~ 17044714 (+)
XLOC_035539 NA coding downstream 298594 17055879 ~ 17059377 (+)
XLOC_035540 si:dkey-190g11.3 coding downstream 312292 17069577 ~ 17075398 (+)
XLOC_035530 NA non-coding upstream 160473 16570336 ~ 16577809 (+)
XLOC_035527 NA non-coding upstream 472471 16259586 ~ 16265811 (+)
XLOC_035542 NA non-coding downstream 329706 17086991 ~ 17126339 (+)
XLOC_035546 NA non-coding downstream 610756 17368041 ~ 17407080 (+)
XLOC_035551 NA non-coding downstream 1205544 17962829 ~ 17968234 (+)

Expression


Co-expression Network