XLOC_003783 (alas1)


Basic Information

Item Value
gene id XLOC_003783
gene name alas1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 260763 ~ 270210 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007288
AGACCTCACTGAACCGTCAGCTATGGACGCCATCATTCGCTGCCCATTCCTGTCCCGCGTCCCGCAGACGTTCCTCCAGCAAGCCAGGAAGTCTCTGGTGGCGTATGCGGTGAAGTGTCCTGTGATGATGGATCTGGCCTCCAGACCCCTGCTGCGCCCGCTCTGCTCCTCTAGCGCCAGCTTCCAGAAGGTGGAAGACTCCTCTGCGGCCGGACATGaaGCCAGTGATGCTCCTGCAGTGCCCGCTGGTCACCCTGCTCCTGCAGCCGGGCATGCCTCCGCCTCTAAATGCCCGTTTCTGGCAGCAGAGATGAGCCAGAAGAACAGCGGTGTGGTCCGGCAGGCCAGCATGGCTCTCCAGGAGGATGTTTCTGAAGTTCGCACCGTGCAGAAAGACGTCTCTGCATCGGCGCTCACTCCTCTGAAGGACGGCATGAATGGAGGAAACCTGATGAAGAAGCTGATGAAGCAGCGTCCCGCTCACGTCTCTCACCTGCTGCAGGACAACATGCCCAAAAATGTGTCCAGCTTTCGTTATGATGAGTTCTTTGAGAAGAAGATCGAGGAGAAGAAGAGCGATCATACGTACCGCGTCTTTAAAACGGTGAACCGCAGAGCCACAGAGTTCCCCATGGCGGACGACTACACCGAGTCTTTATCCTTCAAGAGGAACGTGTCTGTGTGGTGCAGTAATGACTATCTGGGCATGAGCCGCCACCCGCGCGTCGTCCAGACCATCATGGACACTTTAGGAAAGCATGGCTCTGGAGCCGGAGGGACCAGGAATATTTCGGGCACCAGTAAGTTTCATGTGGATCTGGAGCACGAGCTGGCGGATCTCCACGGGAAAGACGCCGCTCTGCTCTTCACCTCCTGCTTTGTGGCTAATGACTCTACGCTCTTCACCCTCGCCAAGATGATGCCGGGTTGTGAGATCTATTCAGACGCAGGCAATCACGCCTCAATGATTCAGGGCATCAGGAACAGCGGCGCCAAGAAGTTTATCTTCCGTCACAACGACGCCAAACATCTACGAGAGCTTCTGGAGAAATCCGATCCGTCCACTCCCAAGATTGTGGCCTTTGAGACGGTGCACTCCATGGACGgcgCAGTGTGTCCACTGGAGCAGCTGTGTGATGTGGCTCATGAGTTCGGCGCGGTCACCTTCGTGGATGAGGTGCATGCGGTGGGTCTGTACGGGCCCCGCGGTGGCGGCATCGGCGATCGGGACTCGGTCATGCACAAGATGGACATCATCTCGGGCACTCTGGgcAAGGCGTTCGGCTGTGTGGGCGGGTACATCGCCAGCACACACGCGCTGGTGGACACGGTGCGCTCGTACGCGGCCGGCTTCATCTTCACCACGTCTCTGCCGCCGATGCTGCTGTCGGGCGCGCGTCAGTCTGTGCAGATCCTGAAGAGCGAAGAGGGACGAACGCTGCGCAGGAAACACCAGCGCAACGTCACACTGCTGCGCCAGATGCTGATGGACAGCGGCCTGCCCGTCATACACTGCCCCAGCCACATCATCCCCGTGCGGGTTGCGGATGCGGAGAAGAACACGGAGGTGTGTGACATCATGATGAGCCGCTACAACATCTACGTTCAGGCCATCAACTACCCGACGGTGGCGCGAGGAGAAGAGCTGCTGCGCATCGCCCCGACACCACACCACACACCCCAGATGATGAAATACTTTGTGGacaaGCTGACGCAGACGTGGACAGAGGTGGGTCTGCCGCTGAAGCCTCACTCCTCCGCCGAGTGTAACTTCTGCCGTCAGCCGCTGCACTTCGAGATCATGAGCGAGAGGGAGAAATCCTACTTCAGCGGCCTCAGCCAGCCCATATCGGCCTGcggataacacacacacacacacacagcgctctGTGTGCTCTTAATCTACAGTCTGAGGTCTTTTATATTTAAGATGTTTATTGTAGGCCAGTCACATGTCCATTCCTGTGTGATCAGCATTATGTGTCTGCTCGTCAGTTTTAATAAactaatgacacacacacacacacaca
>TCONS_00007289
AGACCTCACTGAACCGTCAGCTATGGACGCCATCATTCGCTGCCCATTCCTGTCCCGCGTCCCGCAGACGTTCCTCCAGCAAGCCAGGAAGTCTCTGGTGGCGTATGCGGTGAAGTGTCCTGTGATGATGGATCTGGCCTCCAGACCCCTGCTGCGCCCGCTCTGCTCCTCTAGCGCCAGCTTCCAGAAGGTGGAAGACTCCTCTGCGGCCGGACATGCCAGTGATGCTCCTGCAGTGCCCGCTGGTCACCCTGCTCCTGCAGCCGGGCATGCCTCCGCCTCTAAATGCCCGTTTCTGGCAGCAGAGATGAGCCAGAAGAACAGCGGTGTGGTCCGGCAGGCCAGCATGGCTCTCCAGGAGGATGTTTCTGAAGTTCGCACCGTGCAGAAAGACGTCTCTGCATCGGCGCTCACTCCTCTGAAGGACGGCATGAATGGAGGAAACCTGATGAAGAAGCTGATGAAGCAGCGTCCCGCTCACGTCTCTCACCTGCTGCAGGACAACATGCCCAAAAATGTGTCCAGCTTTCGTTATGATGAGTTCTTTGAGAAGAAGATCGAGGAGAAGAAGAGCGATCATACGTACCGCGTCTTTAAAACGGTGAACCGCAGAGCCACAGAGTTCCCCATGGCGGACGACTACACCGAGTCTTTATCCTTCAAGAGGAACGTGTCTGTGTGGTGCAGTAATGACTATCTGGGCATGAGCCGCCACCCGCGCGTCGTCCAGACCATCATG

Function

symbol description
alas1 Predicted to enable 5-aminolevulinate synthase activity. Acts upstream of or within neutrophil differentiation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including EVL; digestive system; periderm; polster; and pronephros. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1).

GO:

id name namespace
GO:0009058 biosynthetic process biological_process
GO:0048821 erythrocyte development biological_process
GO:0042541 hemoglobin biosynthetic process biological_process
GO:0030223 neutrophil differentiation biological_process
GO:0033014 tetrapyrrole biosynthetic process biological_process
GO:0006778 porphyrin-containing compound metabolic process biological_process
GO:0006782 protoporphyrinogen IX biosynthetic process biological_process
GO:0006783 heme biosynthetic process biological_process
GO:0001666 response to hypoxia biological_process
GO:0005759 mitochondrial matrix cellular_component
GO:0005739 mitochondrion cellular_component
GO:0003870 5-aminolevulinate synthase activity molecular_function
GO:0016740 transferase activity molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function
GO:0030170 pyridoxal phosphate binding molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-001229-2 Predicted to enable 5-aminolevulinate synthase activity. Acts upstream of or within neutrophil differentiation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including EVL; digestive system; periderm; polster; and pronephros. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1).

Ensembl:

ensembl_id ENSDARG00000021059

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007288 False 2030 mRNA 0.57 10 260763 270210
TCONS_00007289 True 739 mRNA 0.58 4 265359 270210

Neighbor

gene id symbol gene type direction distance location
XLOC_003782 dusp7 coding downstream 23997 220544 ~ 236766 (-)
XLOC_003781 NA coding downstream 66048 193460 ~ 194715 (-)
XLOC_003780 CU633745.1 coding downstream 70302 183570 ~ 190461 (-)
XLOC_003779 avil coding downstream 77435 169394 ~ 183328 (-)
XLOC_003778 tegt coding downstream 93312 161196 ~ 167451 (-)
XLOC_003784 npffl coding upstream 5847 276057 ~ 279328 (-)
XLOC_003785 slc11a2 coding upstream 11623 281833 ~ 287670 (-)
XLOC_003786 poc1a coding upstream 35797 306007 ~ 309420 (-)
XLOC_003787 CR855375.2 coding upstream 78903 349113 ~ 351701 (-)
XLOC_003788 NA coding upstream 98917 369127 ~ 369686 (-)
XLOC_003938 BX324177.10 misc upstream 11068594 11338804 ~ 11339100 (-)
XLOC_003942 BX324177.17 misc upstream 11097384 11367594 ~ 11367890 (-)
XLOC_003943 BX324177.3 misc upstream 11100245 11370455 ~ 11370653 (-)
XLOC_003944 BX324177.4 misc upstream 11110694 11380904 ~ 11381204 (-)
XLOC_003945 BX324177.6 misc upstream 11113623 11383833 ~ 11384130 (-)
XLOC_003776 NA non-coding downstream 131597 128158 ~ 129166 (-)
XLOC_003773 CABZ01072245.1 non-coding downstream 189223 61190 ~ 71540 (-)
XLOC_003793 CR855375.4 non-coding upstream 189605 459815 ~ 459930 (-)
XLOC_003797 CU695207.2 non-coding upstream 275251 545461 ~ 548398 (-)
XLOC_003799 CABZ01069324.1 non-coding upstream 329230 599440 ~ 601308 (-)

Expression


Co-expression Network