XLOC_004659 (sh3bp1)


Basic Information

Item Value
gene id XLOC_004659
gene name sh3bp1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 19205086 ~ 19232997 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009231
ATGTGTAAGGACGCTTGTGGTACAGTCTTTTGCCTTTTCAGAGGTGAAGAAGGCCACAGATTCTCCACAATCATGCTGAAGCAGTTTAACATCTTAAAGCAGTTTGGAAATGGGGGGAAGTCACAAGATGCAACTGACCTTCTCACAGATGATCTGGTTTTGGTTGAACAGCGCGTGGAGCCAGCCAAGAAAGCTGCCCAGATCATCCATAAGAAGTTGGTGGGTTGCCTGCAGAGTCAGCAGGGACTGGACTCGGAGAGACGAATGaaaaaattACCCCTCATGATGTTGTCTGTCAGTATGGCTGAGAGCATTAAGGATTTCGATGGTGATTCTTCTATAAGgAAAGTTTTGGAAATGTGCTGCTTCATGCAAAATACCCTGGCGCAGACTTTGGCTGACTTCGAAATGAAACTGGAGAAAGAAGTTCTTGTGCCTCTGAATAAGCTTAGTGagGAGGACTTGCCAGAGATCTTGAAAAACAAAAAGCAGTTTGCTAAACTTACTACAGACTGGAATAATGCTCGTACCAGATCTGAGACCAGCACAGGCCCACAGGCCAAGCAGCACGGACTGAGAGAAGATGTGGAGGAAGCCTGGAGAAGACTGGAGTCTATTAAGGATCAGTACTCTGCAGACCTCTATCATTTTGCCACTAAGGAGGATGACTATGCCAGTTACTTCACCCGTCTTCTAGAACTACAAGCTGAATATCACAAGGCTTCATATGATTTCCTGGAGAGAAACATAACTGAGCTCAAGGAGAGTCACAGCCACACAGAGCCGCTGGTGAGTTCCTCTGAAAATAAGGTATTTGGAGAGCCGCTGCTGTCTCACCTTCAGAGCTGCAGGAGGAAGATTGCTGTCCCCATTGAGGAGTGTGTGAACATGCTGTTACGTACAGGACTCAGGGAGGAGGGGCTGTTCAGACTAGCAGCCGCAGCGTCTGTTATGAAAAAACTGAAAAGCAGTCTGGATTCAGGCACAGTCGACCACACTGAGTTTAGTTCTGACCCTCATGCTGTTGCAGGGGCTCTTAAATGTTACTTGCGAGAACTGCCTGAGCCGCTTATGACGTTTGAACTATACGATGACTGGTTTGAAGCTGCAGGagaAAAAGAAACGGATGAAAAACTAAAGCTGCTCCGGACAGCGTTGCAAAAACTTCCCACAGAAAATTATAACAATCTTAGATACCTTATTCAGTTCCTGTCACAATTATCAGAGCATCAAGCAGTGAATAAGATGACACCCAGTAACATTGCCATTGTGCTCGGTCCTAATCTACTGTGGCCTCGCTGTGAGGGAGAGACATCATTGCTGGACATGGCATCTGCTTCTTCAGTGCAAGTTGTGACTATCATAGAGCCGCTTATACAGCATTCCAAGAGCCTCTTCCCAGAAGaagCTGATTTTGAGGTCCCAGTGCTCCCTGAAAGCCCGCTCTCAACAACATCCCAAAGACCTCTTTCTGACAGCATCTTACCTTCTCCTCCTTTTTCCTCCGGTCGACCATCCATATCAAAAACTGACAGctCAGCCTCCTCTGATGACTTCGGGGTGACAATAGTTGTTAAATCAGCTCCTGTGAACCGCGACGCTGTTGTGTGGGACAACGATTCTGATCCAACCGATCAGCCACTGACACAGGATCACATGCCCACAGCACTTCCTCGTTACACTCCGGTACTCACTCCGAGCCAATCACAGGTTATGCCACAGATCTCCTGCATATCCGAGCCAACTCAGGATCTGCCCACCCAGGAGCCCACATTGAAGATCGCTGGTCCTTATAAACCAAGGAGGTCATTCATCCAACAAAAGGCACCAAACTACACCAAAGGCCTTCTTGTAAGCCCAGCAATGTCATTCCCAACAGCCCAGACAAAGTTGCCTCCTGTTCCATTGCCTAGAGGCTCAGAAATAAAACCACCACTTTCACCCAAGCCAGAAACCATGTTAGTACCACTGCCTACATTACCTGAAGGAGGACCACCAAAGAAACCTCAAGGCAGAAGACCCAAAGTTCCTCCTCCACAACCACCGCAAGCATTGAACAAGCAGCTCTCATCTTCTGCTCAGTGA
>TCONS_00009232
CCGAGTCGAGAGGTGTGCGTACAAATGTGAAACAGTCAAGTGGAGGCTGCTGCTGACACACGTCTGAATGAGATGCCTGTCTAATGAGTCCACAGAGCAAGAACCTTCATCAAATGATACTAAAATACTCTTGAACTGTCTGTACTAACCAAGGAGGTGAAGAAGGCCACAGATTCTCCACAATCATGCTGAAGCAGTTTAACATCTTAAAGCAGTTTGGAAATGGGGGGAAGTCACAAGATGCAACTGACCTTCTCACAGATGATCTGGTTTTGGTTGAACAGCGCGTGGAGCCAGCCAAGAAAGCTGCCCAGATCATCCATAAGAAGTTGGTGGGTTGCCTGCAGAGTCAGCAGGGACTGGACTCGGAGAGACGAATGaaaaaattACCCCTCATGATGTTGTCTGTCAGTATGGCTGAGAGCATTAAGGATTTCGATGGTGATTCTTCTATAAGgAAAGTTTTGGAAATGTGCTGCTTCATGCAAAATACCCTGGCGCAGACTTTGGCTGACTTCGAAATGAAACTGGAGAAAGAAGTTCTTGTGCCTCTGAATAAGCTTAGTGagGAGGACTTGCCAGAGATCTTGAAAAACAAAAAGCAGTTTGCTAAACTTACTACAGACTGGAATAATGCTCGTACCAGATCTGAGACCAGCACAGGCCCACAGGCCAAGCAGCACGGACTGAGAGAAGATGTGGAGGAAGCCTGGAGAAGACTGGAGTCTATTAAGGATCAGTACTCTGCAGACCTCTATCATTTTGCCACTAAGGAGGATGACTATGCCAGTTACTTCACCCGTCTTCTAGAACTACAAGCTGAATATCACAAGGCTTCATATGATTTCCTGGAGAGAAACATAACTGAGCTCAAGGAGAGTCACAGCCACACAGAGCCGCTGGTGAGTTCCTCTGAAAATAAGGTATTTGGAGAGCCGCTGCTGTCTCACCTTCAGAGCTGCAGGAGGAAGATTGCTGTCCCCATTGAGGAGTGTGTGAACATGCTGTTACGTACAGGACTCAGGGAGGAGGGGCTGTTCAGACTAGCAGCCGCAGCGTCTGTTATGAAAAAACTGAAAAGCAGTCTGGATTCAGGCACAGTCGACCACACTGAGTTTAGTTCTGACCCTCATGCTGTTGCAGGGGCTCTTAAATGTTACTTGCGAGAACTGCCTGAGCCGCTTATGACGTTTGAACTATACGATGACTGGTTTGAAGCTGCAGGagaAAAAGAAACGGATGAAAAACTAAAGCTGCTCCGGACAGCGTTGCAAAAACTTCCCACAGAAAATTATAACAATCTTAGATACCTTATTCAGTTCCTGTCACAATTATCAGAGCATCAAGCAGTGAATAAGATGACACCCAGTAACATTGCCATTGTGCTCGGTCCTAATCTACTGTGGCCTCGCTGTGAGGGAGAGACATCATTGCTGGACATGGCATCTGCTTCTTCAGTGCAAGTTGTGACTATCATAGAGCCGCTTATACAGCATTCCAAGAGCCTCTTCCCAGAAGaagCTGATTTTGAGGTCCCAGTGCTCCCTGAAAGCCCGCTCTCAACAACATCCCAAAGACCTCTTTCTGACAGCATCTTACCTTCTCCTCCTTTTTCCTCCGGTCGACCATCCATATCAAAAACTGACAGctCAGCCTCCTCTGATGACTTCGGGGTGACAATAGTTGTTAAATCAGCTCCTGTGAACCGCGACGCTGTTGTGTGGGACAACGATTCTGATCCAACCGATCAGCCACTGACACAGGATCACATGCCCACAGCACTTCCTCGTTACACTCCGGTACTCACTCCGAGCCAATCACAGGTTATGCCACAGATCTCCTGCATATCCGAGCCAACTCAGGATCTGCCCACCCAGGAGCCCACATTGAAGATCGCTGGTCCTTATAAACCAAGGAGGTCATTCATCCAACAAAAGGCACCAAACTACACCAAAGGCCTTCTTGTAAGCCCAGCAATGTCATTCCCAACAGCCCAGACAAAGTTGCCTCCTGTTCCATTGCCTAGAGGCTCAGAAATAAAACCACCACTTTCACCCAAGCCAGAAACCATGTTAGTACCACTGCCTACATTACCTGAAGGAGGACCACCAAAGAAACCTCAAGGCAGAAGACCCAAAGTTCCTCCTCCACAACCACCGCAAGCATTGAACAAGCAGCTCTCATCTTCTGCTCAGTGAAGCCCAAAGGATACTTCATTTCTTTATCTATGAAGAAAATGTAAGTTAGCATAAGTGTGCAGTAGCATGCACAGCCTTTCACAATTACTCTGTGTGACAGTgtgcacaaacacagacacttAACACATGTGCAAGAAAAAGATTCATGTCAGTGTCTCCTAGTGTGATTTATGCCCAGTTAAAAAGAGATTCTGTAGCCAGATTTTGACGCCGTACATTTGGCATCAGGCATGTGTGACTCTTGGGATTGAGTTCAGCACAACACACCTGTAAATTATGGGTGCTTCTCAATGTCTCTACTTATTTTCTCGTTCCTCTGTCCTACGACAGCAAACACCGATCAAGTTCAGCCATCTTGTAGCTATCTTAATTCTCTAAATGCACATTATGATGTCATGAGAAAGGATTCTTTGCGGATGTTTTTATTGACTAAACATGACCCAAGTTATATTAAACCAATTGGCTTGACTATGTCTCCCAGTTATGCTTTCACATTTTCTACAATGTAATGTACTTTTCAGCACAAATTAAAATCAGTTAATAActtatattaattattcattattaaagtCTGAAAGTTGAtgcacttccaactgaaatggaattttaagtagggggcgg

Function

symbol description
sh3bp1 Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of GTPase activity; regulation of Rac protein signal transduction; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human SH3BP1 (SH3 domain binding protein 1).

GO:

id name namespace
GO:0043547 positive regulation of GTPase activity biological_process
GO:0035020 regulation of Rac protein signal transduction biological_process
GO:0032956 regulation of actin cytoskeleton organization biological_process
GO:0007165 signal transduction biological_process
GO:0005829 cytosol cellular_component
GO:0005622 intracellular anatomical structure cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005096 GTPase activator activity molecular_function

KEGG:

id description
ko04131 Membrane trafficking
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-121128-2 Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of GTPase activity; regulation of Rac protein signal transduction; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to human SH3BP1 (SH3 domain binding protein 1).

Ensembl:

ensembl_id ENSDARG00000078119

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009231 False 2085 mRNA 0.48 19 19205086 19232376
TCONS_00009232 True 2819 mRNA 0.45 18 19208338 19232997

Neighbor

gene id symbol gene type direction distance location
XLOC_004658 pdap1a coding upstream 642 19199735 ~ 19204444 (+)
XLOC_004657 slc16a8 coding upstream 6315 19191787 ~ 19198771 (+)
XLOC_004656 cby1 coding upstream 13407 19188542 ~ 19191679 (+)
XLOC_004655 phf5a coding upstream 61394 19138452 ~ 19143692 (+)
XLOC_004654 kctd17 coding upstream 139788 19036380 ~ 19065298 (+)
XLOC_004660 NA coding downstream 34762 19267759 ~ 19271156 (+)
XLOC_004661 tnrc6b coding downstream 48192 19281189 ~ 19301988 (+)
XLOC_004662 csnk1e coding downstream 72393 19305390 ~ 19340220 (+)
XLOC_004663 tomm22 coding downstream 115541 19348538 ~ 19353771 (+)
XLOC_004664 dmc1 coding downstream 123626 19356623 ~ 19362186 (+)
XLOC_004648 NA non-coding upstream 337111 18861278 ~ 18867975 (+)
XLOC_004644 AL772266.2 non-coding upstream 606122 18598850 ~ 18598964 (+)
XLOC_004635 NA non-coding upstream 977082 18209871 ~ 18228004 (+)
XLOC_004634 BX005075.1 non-coding upstream 1079312 18125658 ~ 18125774 (+)
XLOC_004625 NA non-coding upstream 1777706 17424431 ~ 17427380 (+)
XLOC_004667 BX649366.2 non-coding downstream 155146 19388143 ~ 19388273 (+)
XLOC_004670 NA non-coding downstream 225812 19458809 ~ 19459285 (+)
XLOC_004675 NA non-coding downstream 1030588 20263585 ~ 20265465 (+)
XLOC_004679 NA non-coding downstream 1258622 20491619 ~ 20504801 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000063_02293142_02305535 SH3BP1 coding CI01000063 null 2292193 ~ 2305535 (-)