hmbsa (hmbs,hmbsa,LOC107717875,LOC107722788)


Basic Information

Item Value
gene id hmbsa
gene name hmbs,hmbsa,LOC107717875,LOC107722788
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047621.1
NCBI id CM018567.1
chromosome length 18889892
location 8467213 ~ 8482453 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026922074.2
GAACACCACCGGCTCTGCGCCGCATTAGTGGGAACCGAGTTAGCAGCGAGGTCACGAGGATATACTCTTGGTAGCTGGTGAAGAAAGTCagttaaatatgcaaaaacagaTACTTTTTTCACTTCCGTGATTAGAAATTCTTGCATGAAAAAGCAACTTTTATCGTCGTTGTTCGTTTTTCCCGGCAAGGAAGATGTCTCAAGAAGTTAGTACTACTGAAGAAGAAAATGGAACAGTCACTCGGATTATTCGCATCGGAACCAGGAAAAGCCAGCTGGCTCGGATTCAGACAGACAGCGTGGCCGAGAAACTGAAAGAGCTCTATCCAGACTTGCAGCTAGAGATAGttGCCATGTCGACAATCGGAGACAAAATCCTTGACACTGCCTTATCAAAGATTGGAGAGAAGAGTCTGTTCACCAAAGAGCTGGAGAATGCCCTTGAGAGAAACGAGGTGGACCTTGTTGTGCACTCTCTAAAAGACCTTCCTACCTCACTGCCTCCTGGTTTCACCATCGGTGCTGTTCTCCAACGTGAAAATCCTCATGATGCTGTAGTGCTTCATCCAAAGAATGCTGGACTCACTCTGGACACCCTGCCAGAAAAGAGTGTGATTGGCACGAGCTCGCTCCGCCGAGCGGCACAGCTGAAAAAAAGGTTCCCACAGCTGGAATTTGAAAACATTAGAGGCAACCTGAATACTCGTCTGAAGAAGCTGGATGAGAAGGATGACTACGCTGCCATCATTCTGGCTGCAGCTGGTCTCAAGCGCATGGGCTGGGAGAGCCGTATCAGTCAGGTTCTGGGTCCTGAAGACTGCATGTATGCTGTAGGCCAGGGAGCGTTGGCGGTGGAAGTGAGggcaagagacagagacattCTCAAGATGGTGTCCATCCTCCACCACCCTGACACTGTGCTGCGCTGCATCTCTGAGAGGGCTTTCCTCAAGCAGCTGGAGGGAGGCTGCAGTGTACCTGTCGCTGTCCACACAGAAGTGAAGAACTCGGTgCTCTATTTGACAGGTGCAGTTTACAGTCTGGATGGTGCTGACTGCTTGAAGGACACCATGCAAACCAACATCGAATTAGATAACATGGTGCACGACAGCGCAGAAGAGCGCGCTCATGTCGGAGTCACAGCCAACAACATATCGCTGATGGCTCTGGATGCTGCAGACAAGCTGGGTGTTGATCTTGCCAACCTGCTGCTCAGTAAAGGAGCCAAGGACATCCTTACCACGGCCAGACAGCTCAACGATGTCCGATAACAGCTTCTTTCAGCCGCCAGCCAACCCTGATCCACATGATAACACTGCCAACatgaaaaatgcacacacacattcaaagtGAAGGTCAGGGGTGTAAACAGTGCTATTTAAATGGATGCAACAGAATGAGTGTATGCCTCTGTTTACCAATGTCATCCCAACACATGTTTTCAGCACTGAATGCATTGATGATTATATTTATCTTCAGTACTTTGACAGTACTAGAACAAACCATGTACATGCTGATTTCTTGATTACCATGGCAAGTAACTTTAACTCAGGTGCACTCAGGAAAAAGAGGTTCTTTGGCAAGTTAAAGCTTCCCAGACAGGGTTTTTACATGTAACCTTTTTGAGTGTAGCTGGTGGTCAGTAGGTCTGAGTTCTCTTTAATAATATTCTATGCTGAAACCATGGTTATATAAACAAATCAGATTTAGTGAGGTTGTACCTTTTATTATTTAGTCATGAAGCATTTTGCAGCTTCATTTATTCTCTTCTATGTCGCCTGAACCTATACTTTATATCCTCATTGCAGTAATACTTGGTGTCATTTAATTTTAGCACACTCGTGCCTTCCAGTACTCACTGCTGCCTCTTAAGAGGCCTGGCACAGATTAAAGGTGCCCAGATTTTCAGTAGCCATCATTAATAGTGTTAAAGGAATAAATCCTTTAAATGTGAACAAATTTCCTGTTTACCAGCCAAGATCTCTGGTGTTCagagtttgctttttttttagtttcacaCCATAGCTGTAAGACTAACACAGCAACTACAGTTgtacataaatttataaatgaagcAGAATGgatatgcattttaaaatttagatACTGAGGTTTCAAATTGCTGCCACTAATCCATCCACTTCATCCATGTTTATAGATAACAGTATGTCACAGAAGGTTGGGTATGTTTGAGGTCActacacaccaccaccaccataataataataataattattattattattattattattagtggttagcactgttgcctcacacctccagggttagaggtttgaatcccgcctccaccctgtgtgcatggagtttgcatgttctcacgggggtttcctctgggtactccagtttcctccccagtccaaagacatgcattgtggCTGAATTGCATATCCACATTgtctgtcgtgtgtgtgtgcagttttgccCTGCGTTGGACTGGCACCCCtggtccagggtgtcccccacctagTACCCCGGATCCCCTGGGattccatctatccatccattcctcCAGAATTCCTCCATTCCTccagaatgaatggatggaataATATATTGTTCTGACAatctaccagctgccaaaacacaggccaagCTGATAGTCTGACTTACTAGTCTGAATTACTTCACTAAATGAATCAGTACATAACTGAGATTTTCAAATTTGCCTTACTGTCGTGTTATTTTCTTAAGAGTAACTTGTAGCATTAGTAATAGTAAAACATTACCATTTCACAAGTTCACAAGTTGTTTCCTTTCTACCAGCCCTTAACAGCTAGCAAAGGCGGCCTGTGATTTAGCAGCTTGTCAGActcagttttttcccccagcagGGTTGTGTGTTAATTTCAGCATTGTTTGCATGTTAATCATATCTCTGCACACAGTGGTaatataaagaaacaaaatatggACACCAGACATGTCTTGGCTATTTAAGCTAAGTAGGAAATGCATAAATTCCACTTTCCCGGATCAGGTCCTTCAATGCAGGGCTGAAGTGTGTGCTCAGGAAGTAAAGTAAACATGGCTGTAATGTTCTCAGTAGGAAGGGTGCAGGCTGAGAGACTCACTGTTCAATACTGAATCATTTATGGGTTGGGTCTGATGCCAGGAAGCTGTTTCTAGTGCCTGAGACGTGCCTTAATGCCATAATACAATCTGTAAAATGCATAAActactgaaaataaagatttatttctTCACTATTATTTCA
>XM_026922075.2
GAGGGTGGATTAAGACCTTAAAGAAGGGACAGCTTTCCTTTCCGAGCCACCACCCCAGAGTTCATTCATTAGCAGGGTCTGGAGACAAGTGCACTtcatcttaaatatttaaactagCTAAAGGCTTAAGGGATAAGATGGAAGGGCCATTTAAGTGTATACGAGAAGAAAATGGAACAGTCACTCGGATTATTCGCATCGGAACCAGGAAAAGCCAGCTGGCTCGGATTCAGACAGACAGCGTGGCCGAGAAACTGAAAGAGCTCTATCCAGACTTGCAGCTAGAGATAGttGCCATGTCGACAATCGGAGACAAAATCCTTGACACTGCCTTATCAAAGATTGGAGAGAAGAGTCTGTTCACCAAAGAGCTGGAGAATGCCCTTGAGAGAAACGAGGTGGACCTTGTTGTGCACTCTCTAAAAGACCTTCCTACCTCACTGCCTCCTGGTTTCACCATCGGTGCTGTTCTCCAACGTGAAAATCCTCATGATGCTGTAGTGCTTCATCCAAAGAATGCTGGACTCACTCTGGACACCCTGCCAGAAAAGAGTGTGATTGGCACGAGCTCGCTCCGCCGAGCGGCACAGCTGAAAAAAAGGTTCCCACAGCTGGAATTTGAAAACATTAGAGGCAACCTGAATACTCGTCTGAAGAAGCTGGATGAGAAGGATGACTACGCTGCCATCATTCTGGCTGCAGCTGGTCTCAAGCGCATGGGCTGGGAGAGCCGTATCAGTCAGGTTCTGGGTCCTGAAGACTGCATGTATGCTGTAGGCCAGGGAGCGTTGGCGGTGGAAGTGAGggcaagagacagagacattCTCAAGATGGTGTCCATCCTCCACCACCCTGACACTGTGCTGCGCTGCATCTCTGAGAGGGCTTTCCTCAAGCAGCTGGAGGGAGGCTGCAGTGTACCTGTCGCTGTCCACACAGAAGTGAAGAACTCGGTgCTCTATTTGACAGGTGCAGTTTACAGTCTGGATGGTGCTGACTGCTTGAAGGACACCATGCAAACCAACATCGAATTAGATAACATGGTGCACGACAGCGCAGAAGAGCGCGCTCATGTCGGAGTCACAGCCAACAACATATCGCTGATGGCTCTGGATGCTGCAGACAAGCTGGGTGTTGATCTTGCCAACCTGCTGCTCAGTAAAGGAGCCAAGGACATCCTTACCACGGCCAGACAGCTCAACGATGTCCGATAACAGCTTCTTTCAGCCGCCAGCCAACCCTGATCCACATGATAACACTGCCAACatgaaaaatgcacacacacattcaaagtGAAGGTCAGGGGTGTAAACAGTGCTATTTAAATGGATGCAACAGAATGAGTGTATGCCTCTGTTTACCAATGTCATCCCAACACATGTTTTCAGCACTGAATGCATTGATGATTATATTTATCTTCAGTACTTTGACAGTACTAGAACAAACCATGTACATGCTGATTTCTTGATTACCATGGCAAGTAACTTTAACTCAGGTGCACTCAGGAAAAAGAGGTTCTTTGGCAAGTTAAAGCTTCCCAGACAGGGTTTTTACATGTAACCTTTTTGAGTGTAGCTGGTGGTCAGTAGGTCTGAGTTCTCTTTAATAATATTCTATGCTGAAACCATGGTTATATAAACAAATCAGATTTAGTGAGGTTGTACCTTTTATTATTTAGTCATGAAGCATTTTGCAGCTTCATTTATTCTCTTCTATGTCGCCTGAACCTATACTTTATATCCTCATTGCAGTAATACTTGGTGTCATTTAATTTTAGCACACTCGTGCCTTCCAGTACTCACTGCTGCCTCTTAAGAGGCCTGGCACAGATTAAAGGTGCCCAGATTTTCAGTAGCCATCATTAATAGTGTTAAAGGAATAAATCCTTTAAATGTGAACAAATTTCCTGTTTACCAGCCAAGATCTCTGGTGTTCagagtttgctttttttttagtttcacaCCATAGCTGTAAGACTAACACAGCAACTACAGTTgtacataaatttataaatgaagcAGAATGgatatgcattttaaaatttagatACTGAGGTTTCAAATTGCTGCCACTAATCCATCCACTTCATCCATGTTTATAGATAACAGTATGTCACAGAAGGTTGGGTATGTTTGAGGTCActacacaccaccaccaccataataataataataattattattattattattattattagtggttagcactgttgcctcacacctccagggttagaggtttgaatcccgcctccaccctgtgtgcatggagtttgcatgttctcacgggggtttcctctgggtactccagtttcctccccagtccaaagacatgcattgtggCTGAATTGCATATCCACATTgtctgtcgtgtgtgtgtgcagttttgccCTGCGTTGGACTGGCACCCCtggtccagggtgtcccccacctagTACCCCGGATCCCCTGGGattccatctatccatccattcctcCAGAATTCCTCCATTCCTccagaatgaatggatggaataATATATTGTTCTGACAatctaccagctgccaaaacacaggccaagCTGATAGTCTGACTTACTAGTCTGAATTACTTCACTAAATGAATCAGTACATAACTGAGATTTTCAAATTTGCCTTACTGTCGTGTTATTTTCTTAAGAGTAACTTGTAGCATTAGTAATAGTAAAACATTACCATTTCACAAGTTCACAAGTTGTTTCCTTTCTACCAGCCCTTAACAGCTAGCAAAGGCGGCCTGTGATTTAGCAGCTTGTCAGActcagttttttcccccagcagGGTTGTGTGTTAATTTCAGCATTGTTTGCATGTTAATCATATCTCTGCACACAGTGGTaatataaagaaacaaaatatggACACCAGACATGTCTTGGCTATTTAAGCTAAGTAGGAAATGCATAAATTCCACTTTCCCGGATCAGGTCCTTCAATGCAGGGCTGAAGTGTGTGCTCAGGAAGTAAAGTAAACATGGCTGTAATGTTCTCAGTAGGAAGGGTGCAGGCTGAGAGACTCACTGTTCAATACTGAATCATTTATGGGTTGGGTCTGATGCCAGGAAGCTGTTTCTAGTGCCTGAGACGTGCCTTAATGCCATAATACAATCTGTAAAATGCATAAActactgaaaataaagatttatttctTCACTATTATTTCA
>XM_034300768.1
CGTCATGTGATACAGGGAGGAAGAAAATGGAACAGTCACTCGGATTATTCGCATCGGAACCAGGAAAAGCCAGCTGGCTCGGATTCAGACAGACAGCGTGGCCGAGAAACTGAAAGAGCTCTATCCAGACTTGCAGCTAGAGATAGttGCCATGTCGACAATCGGAGACAAAATCCTTGACACTGCCTTATCAAAGATTGGAGAGAAGAGTCTGTTCACCAAAGAGCTGGAGAATGCCCTTGAGAGAAACGAGGTGGACCTTGTTGTGCACTCTCTAAAAGACCTTCCTACCTCACTGCCTCCTGGTTTCACCATCGGTGCTGTTCTCCAACGTGAAAATCCTCATGATGCTGTAGTGCTTCATCCAAAGAATGCTGGACTCACTCTGGACACCCTGCCAGAAAAGAGTGTGATTGGCACGAGCTCGCTCCGCCGAGCGGCACAGCTGAAAAAAAGGTTCCCACAGCTGGAATTTGAAAACATTAGAGGCAACCTGAATACTCGTCTGAAGAAGCTGGATGAGAAGGATGACTACGCTGCCATCATTCTGGCTGCAGCTGGTCTCAAGCGCATGGGCTGGGAGAGCCGTATCAGTCAGGTTCTGGGTCCTGAAGACTGCATGTATGCTGTAGGCCAGGGAGCGTTGGCGGTGGAAGTGAGggcaagagacagagacattCTCAAGATGGTGTCCATCCTCCACCACCCTGACACTGTGCTGCGCTGCATCTCTGAGAGGGCTTTCCTCAAGCAGCTGGAGGGAGGCTGCAGTGTACCTGTCGCTGTCCACACAGAAGTGAAGAACTCGGTgCTCTATTTGACAGGTGCAGTTTACAGTCTGGATGGTGCTGACTGCTTGAAGGACACCATGCAAACCAACATCGAATTAGATAACATGGTGCACGACAGCGCAGAAGAGCGCGCTCATGTCGGAGTCACAGCCAACAACATATCGCTGATGGCTCTGGATGCTGCAGACAAGCTGGGTGTTGATCTTGCCAACCTGCTGCTCAGTAAAGGAGCCAAGGACATCCTTACCACGGCCAGACAGCTCAACGATGTCCGATAACAGCTTCTTTCAGCCGCCAGCCAACCCTGATCCACATGATAACACTGCCAACatgaaaaatgcacacacacattcaaagtGAAGGTCAGGGGTGTAAACAGTGCTATTTAAATGGATGCAACAGAATGAGTGTATGCCTCTGTTTACCAATGTCATCCCAACACATGTTTTCAGCACTGAATGCATTGATGATTATATTTATCTTCAGTACTTTGACAGTACTAGAACAAACCATGTACATGCTGATTTCTTGATTACCATGGCAAGTAACTTTAACTCAGGTGCACTCAGGAAAAAGAGGTTCTTTGGCAAGTTAAAGCTTCCCAGACAGGGTTTTTACATGTAACCTTTTTGAGTGTAGCTGGTGGTCAGTAGGTCTGAGTTCTCTTTAATAATATTCTATGCTGAAACCATGGTTATATAAACAAATCAGATTTAGTGAGGTTGTACCTTTTATTATTTAGTCATGAAGCATTTTGCAGCTTCATTTATTCTCTTCTATGTCGCCTGAACCTATACTTTATATCCTCATTGCAGTAATACTTGGTGTCATTTAATTTTAGCACACTCGTGCCTTCCAGTACTCACTGCTGCCTCTTAAGAGGCCTGGCACAGATTAAAGGTGCCCAGATTTTCAGTAGCCATCATTAATAGTGTTAAAGGAATAAATCCTTTAAATGTGAACAAATTTCCTGTTTACCAGCCAAGATCTCTGGTGTTCagagtttgctttttttttagtttcacaCCATAGCTGTAAGACTAACACAGCAACTACAGTTgtacataaatttataaatgaagcAGAATGgatatgcattttaaaatttagatACTGAGGTTTCAAATTGCTGCCACTAATCCATCCACTTCATCCATGTTTATAGATAACAGTATGTCACAGAAGGTTGGGTATGTTTGAGGTCActacacaccaccaccaccataataataataataattattattattattattattattagtggttagcactgttgcctcacacctccagggttagaggtttgaatcccgcctccaccctgtgtgcatggagtttgcatgttctcacgggggtttcctctgggtactccagtttcctccccagtccaaagacatgcattgtggCTGAATTGCATATCCACATTgtctgtcgtgtgtgtgtgcagttttgccCTGCGTTGGACTGGCACCCCtggtccagggtgtcccccacctagTACCCCGGATCCCCTGGGattccatctatccatccattcctcCAGAATTCCTCCATTCCTccagaatgaatggatggaataATATATTGTTCTGACAatctaccagctgccaaaacacaggccaagCTGATAGTCTGACTTACTAGTCTGAATTACTTCACTAAATGAATCAGTACATAACTGAGATTTTCAAATTTGCCTTACTGTCGTGTTATTTTCTTAAGAGTAACTTGTAGCATTAGTAATAGTAAAACATTACCATTTCACAAGTTCACAAGTTGTTTCCTTTCTACCAGCCCTTAACAGCTAGCAAAGGCGGCCTGTGATTTAGCAGCTTGTCAGActcagttttttcccccagcagGGTTGTGTGTTAATTTCAGCATTGTTTGCATGTTAATCATATCTCTGCACACAGTGGTaatataaagaaacaaaatatggACACCAGACATGTCTTGGCTATTTAAGCTAAGTAGGAAATGCATAAATTCCACTTTCCCGGATCAGGTCCTTCAATGCAGGGCTGAAGTGTGTGCTCAGGAAGTAAAGTAAACATGGCTGTAATGTTCTCAGTAGGAAGGGTGCAGGCTGAGAGACTCACTGTTCAATACTGAATCATTTATGGGTTGGGTCTGATGCCAGGAAGCTGTTTCTAGTGCCTGAGACGTGCCTTAATGCCATAATACAATCTGTAAAATGCATAAActactgaaaataaagatttatttctTCACTATTATTTCA

Function

symbol description
hmbsa Predicted to enable hydroxymethylbilane synthase activity. Predicted to be involved in heme biosynthetic process. Predicted to act upstream of or within peptidyl-pyrromethane cofactor linkage and porphyrin-containing compound biosynthetic process. Predicted to be active in cytoplasm. Is expressed in intermediate mesoderm. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Orthologous to human HMBS (hydroxymethylbilane synthase).
hmbs Enables hydroxymethylbilane synthase activity. Involved in heme biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Implicated in acute intermittent porphyria and sickle cell anemia. Biomarker of prostate carcinoma; seminoma; and urinary bladder cancer.

NR:

description
porphobilinogen deaminase isoform X1

GO:

id name namespace
GO:0018160 peptidyl-pyrromethane cofactor linkage biological_process
GO:0033014 tetrapyrrole biosynthetic process biological_process
GO:0004418 hydroxymethylbilane synthase activity molecular_function

KEGG:

id description
K01749 hemC, HMBS; hydroxymethylbilane synthase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026922074.2 True 3237 mRNA 0.44 14 8467213 8481038
XM_026922075.2 False 3181 mRNA 0.44 14 8467213 8478777
XM_034300768.1 False 3036 mRNA 0.44 14 8467213 8482453

Neighbor

gene id symbol gene type direction distance location
dpagt1 dpagt1,LOC107587348,LOC107722798,LOC107717886,LOC107597531 coding downstream 51033 8407590 ~ 8416180 (-)
abcg4a abcg4,abcg4a,LOC108261268,LOC108429752,LOC107717882,LOC107722792,LOC107677424,LOC107587350 coding downstream 87771 8352400 ~ 8379442 (-)
atp5l atp5l,LOC107664523,LOC107597515,LOC108233819,LOC107098727,LOC107587353,LOC107387014 coding downstream 130966 8332432 ~ 8336247 (-)
ftr83 LOC108260410,LOC108429748,LOC107712363,LOC107587475,LOC107677412,LOC107664511,LOC107722782 coding downstream 154798 8306374 ~ 8312415 (-)
ruvbl2 ruvbl2,LOC105888489,LOC107664527,LOC107722783 coding downstream 163249 8288568 ~ 8303964 (-)
stk36 LOC108260317,LOC108271363,LOC107722762,LOC107598122 coding upstream 84832 8567285 ~ 8579445 (-)
c27h11orf53 c28h11orf53,cunh11orf53,LOC107597648 coding upstream 97644 8580097 ~ 8590527 (-)
adamts15a LOC108260351 coding upstream 273186 8755639 ~ 8775242 (-)
usf1l LOC108259962,LOC103042741 coding upstream 607274 9089727 ~ 9101289 (-)
thy1 NA coding upstream 623123 9105576 ~ 9108781 (-)
G383386 NA non-coding downstream 147420 8319585 ~ 8319793 (-)
LOC117596218 NA non-coding downstream 182902 8270854 ~ 8284311 (-)
G383366 NA non-coding downstream 304048 8162782 ~ 8163165 (-)
G383362 NA non-coding downstream 313206 8151418 ~ 8154007 (-)
G383359 NA non-coding downstream 318857 8147877 ~ 8148356 (-)
G383515 NA non-coding upstream 28138 8510591 ~ 8510815 (-)
G383522 NA non-coding upstream 33908 8516361 ~ 8517669 (-)
G383523 NA non-coding upstream 35991 8518444 ~ 8518890 (-)
G383526 NA non-coding upstream 39244 8521697 ~ 8522292 (-)
G383527 LOC108260305 non-coding upstream 42855 8525308 ~ 8526588 (-)
G383467 h2afx,LOC106516344,LOC107677420,LOC104950138,LOC100693699,LOC108260105,LOC106527800 other downstream 201 8466359 ~ 8467012 (-)
hinfp hinfp,LOC107677425,LOC107662995 other downstream 68858 8382695 ~ 8398355 (-)
pdzd3b LOC108260234 other downstream 118944 8338508 ~ 8348269 (-)
atp2a3 atp2a3,LOC107587360,LOC107597397,LOC107712375,LOC107664518,LOC107748501 other downstream 480480 7889060 ~ 7986733 (-)
camkk1a camkk1,LOC107664416,LOC107587369,LOC107664519 other downstream 571484 7799638 ~ 7895729 (-)
timm8b timm8b,LOC107598437,LOC107717885 other upstream 355225 8837678 ~ 8839764 (-)
LOC113531288 NA other upstream 436957 8919410 ~ 9008686 (-)
ubash3ba ubash3b,ubash3ba,LOC108259961,LOC106602883,LOC107597727,LOC101074361 other upstream 538262 9020715 ~ 9070259 (-)
f11r.1 f11r other upstream 591299 9073752 ~ 9084084 (-)
LOC113531664 NA other upstream 758263 9240716 ~ 9255445 (-)

Expression


Co-expression Network