XLOC_006852 (sfrp5)


Basic Information

Item Value
gene id XLOC_006852
gene name sfrp5
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 39911551 ~ 39947335 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00013176
ACACACTAGGTGCACTTCAGTCAAACTAGACAAGAGCTCTGCTGCAGTTTCTGTTAAACCACAGGACAGAAGCAGAAAAGGAGGGAAAccccagatttttattttatttcttaaacacaacaaaaaaaaaggattaacaTTTAGATTTTGAAAATTTTGATTTACACTTACCCCCCCGTTCTCCTGAATCACAGCAGAGGATGGCGGAGCTGAAGAGGCAGGTGTCTCTGACCCAGGCTGTGACCCTGGCGCTGGTTCTACTCACTTCAGCCTCTTCGGCAGAGGAGTACGACTACTACAGCTGGCAGTCGGACAATTTCCACAGCGGCCGCTTCTATGCCAAGCAGCCGCAGTGTGTGGATATCCCAGCCGACCTGCGGCTCTGCTACAACGTGGGCTACAAAAAGATGCGCCTGCCAAACCTATTGGACCACGAGACCATGCCTGAGGTCAAGCAGCAGGCTGGCAGCTGGGTGCCGCTTCTAGCAAAGCGATGCCACGCTGACACGCAGGTGTTCCTCTGCTCACTGTTTGCTCCGGTGTGCCTGGACCGGCCCATCTACCCCTGCAGGTCTCTGTGTGAGGCGGTGCGGGACAGCTGCGCCCCGGTCATGGAGACCTACGGCTTTCCCTGGCCGGAGATGCTACAGTGTGAGAAGTTCCCCATCGATAATGATCTATGCATTCCTATGCAGTTCTCCGCAGGACACGTCACTCAGACTCCAGTTTCCAAAGTGTGTCCACCCTGTGACAACGAGTTGAAAGCCGACACCATAATGGAGCACTACTGCGCCAGTGATTTTGCACTCAAGATGAAAATTAAAGAGGCGAAAAAGGAAAAAGGCGACCGCAAGCTCATCGCAGCGCAAAAGAAAAAGAAGGTTCTGAAAATGGGAATACTGAGAAAGAAAGACCTAAAGAAGCTCACTCTATACATCAAGAATGGAGCCAACTGCCCCTGCTCACAACTGGACAACCTAGGGAGCAACTTCCTTATCATGGGCCGCAAAGTAGACCAGCAGCTACTGCTCATGTCCATCCACAAGTGGGACAAAAAGAGCAAGGAACTCAAGTTTGCCATTAAATACATCAAGTCTCAGCAGTGTCCCACCTATCACAGTGTCTTCCAGTGACCAATGACTTTTTGGTGGTCTTCCAATAACTCTTTCAGAGACTGTATCCATGCCTAATTCCGACCATTAGTACAGATGTATTTTATAACTCAAGAAACGGCTTTTGGAAACTGCTTAGGACTTAATCCATCATCAAGTACAGCTACGTTCTGTTGGCAACTGTATCtgcataaaaagttattgtttatGAAGCAATCAGCACACTTACGATACTCATGCATATATTTTAGGGAAACTTTCCTGTTTCAGActacagggtttttttttttttttttttggaaagacaTTGACGACCCTTTCAATCAACATGAGAAAGAAAATTGTGAACAAAAGCTTTAAAGTTAATGAGCACATATTTGATTTCAGTGGCCAGATTCCATTTAAAAGAGTGAAAAAAGAGCAAACATGGTGCCAACTGGGTTTTATTTGTATCTTCTATTTTGTAGATAAggaataaaaagtttttattatataCCACATTGACACAATCGTGATCATTAGCACCAGATTGAGACATAAGTCGGGTTGTGGCTTGAATCTTGGGAGGTAAGACAGCTGATGGATTGAAAAGTGTTGGTCAGGATGGCAGCCCAAATACATCAACCGCAGGCCAGTGAGCAAGTCTGGACAATATCATATTGGCCGAGCTCATGACAGACTATGGACTCGTTCGAGCAGTTTGGTTGGTGAGGTGTTTCTATTCTGCTTTCTATACAGTATGCaactgtgttttcttttttactaaagttattatatattgcTACAAACCTATGTACAGTACATGGTATGAAAAGAGCCTTCCAACATTTCATCTGACTGTAATAAAGGATAACATTTAACTGA

Function

symbol description
sfrp5 Predicted to enable Wnt-protein binding activity. Acts upstream of with a negative effect on canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Acts upstream of or within animal organ development; endodermal digestive tract morphogenesis; and regulation of signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including anterior neural keel; anterior neural rod; gut; immature eye; and nervous system. Orthologous to human SFRP5 (secreted frizzled related protein 5).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0030111 regulation of Wnt signaling pathway biological_process
GO:0061386 closure of optic fissure biological_process
GO:0035567 non-canonical Wnt signaling pathway biological_process
GO:0030177 positive regulation of Wnt signaling pathway biological_process
GO:0007275 multicellular organism development biological_process
GO:0030510 regulation of BMP signaling pathway biological_process
GO:0030513 positive regulation of BMP signaling pathway biological_process
GO:0090090 negative regulation of canonical Wnt signaling pathway biological_process
GO:2000056 regulation of Wnt signaling pathway involved in digestive tract morphogenesis biological_process
GO:0061031 endodermal digestive tract morphogenesis biological_process
GO:0001654 eye development biological_process
GO:0072576 liver morphogenesis biological_process
GO:0030900 forebrain development biological_process
GO:0060059 embryonic retina morphogenesis in camera-type eye biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0017147 Wnt-protein binding molecular_function

KEGG:

id description
ko04310 Wnt signaling pathway
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-011108-2 Predicted to enable Wnt-protein binding activity. Acts upstream of with a negative effect on canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Acts upstream of or within animal organ development; endodermal digestive tract morphogenesis; and regulation of signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including anterior neural keel; anterior neural rod; gut; immature eye; and nervous system. Orthologous to human SFRP5 (secreted frizzled related protein 5).

Ensembl:

ensembl_id ENSDARG00000039041

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00013176 True 1976 mRNA 0.45 3 39911551 39947335

Neighbor

gene id symbol gene type direction distance location
XLOC_006851 zgc:171482 coding downstream 80552 39656610 ~ 39830999 (-)
XLOC_006850 NA coding downstream 407058 39499592 ~ 39504493 (-)
XLOC_006849 slc35f3b coding downstream 511584 39346298 ~ 39399967 (-)
XLOC_006848 BX324188.2 coding downstream 668879 39242555 ~ 39242672 (-)
XLOC_006847 col9a1b coding downstream 751533 39119460 ~ 39160018 (-)
XLOC_006853 crtac1b coding upstream 117146 40064481 ~ 40141630 (-)
XLOC_006854 loxl4 coding upstream 235152 40182487 ~ 40238813 (-)
XLOC_006855 zgc:123010 coding upstream 300044 40247379 ~ 40282770 (-)
XLOC_006856 pyroxd2 coding upstream 337537 40284872 ~ 40316367 (-)
XLOC_006857 nkx3.3 coding upstream 450182 40397517 ~ 40401870 (-)
XLOC_006471 BX537274.2 misc downstream 29646646 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 39085326 825904 ~ 826225 (-)
XLOC_006846 BX323574.1 non-coding downstream 1058299 38853137 ~ 38853252 (-)
XLOC_006843 NA non-coding downstream 1291832 38613225 ~ 38619719 (-)
XLOC_006842 NA non-coding downstream 1716337 38190521 ~ 38195214 (-)
XLOC_006859 NA non-coding upstream 470981 40418316 ~ 40419308 (-)
XLOC_006863 NA non-coding upstream 1014400 40961735 ~ 40977410 (-)
XLOC_006864 NA non-coding upstream 1064497 41011832 ~ 41114062 (-)
XLOC_006866 BX548002.1 non-coding upstream 1282958 41230293 ~ 41230409 (-)
XLOC_006867 CABZ01117863.1 non-coding upstream 1715637 41662972 ~ 41663088 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000012_02884547_02903687 SFRP5 coding CI01000012 null 2884547 ~ 2903687 (+)
bowfin (Amia calva) AMCG00003054 sfrp5,LOC107747303,LOC107564685,LOC107665568,LOC107728441,LOC107601040 coding CM030139.1 CM030139.1 10517867 ~ 10519484 (-)