CI01000004_07164273_07167923 (BMI1B, BMI1)


Basic Information

Item Value
gene id CI01000004_07164273_07167923
gene name BMI1B, BMI1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000004
NCBI id null
chromosome length 17451736
location 7164273 ~ 7168236 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000004_07164273_07167923.mRNA
ATGACTCGGTTATCTGCAGTATGGGCTAAACTGTCAGATTACTCCTACCAATATCGCAGTCGAGACACAGCGGGCTCACAGACGCGAGCTCTCGAGCTTCCGTTGACTGTGTTCCTCACTGAAGACATCGGAAAGGCAGGGAAGGTGTATTCTCTATCACATTTGGAAGCGATGCGTGCTGAAATGGTGGTTGTACGACGTGTTTACGTTATAGTGATAACTGCTTCTTCAACAATAGTGTGCGGTCGGCGAACTCACATGACAATGCACCGAACAACAAGAATCAAGATAACGGAGCTCAATCCTCATTTGATGTGCGTTTTATGTGGAGGATATTTCATTGACGCGACCACCATTGTCGAATGTTTGCATTCATTTTGCAAAATGTGCATTGTGAGGTATCTGGAGACCAGCAAATACTGTCCTATTTGTGATGTCCAAGTTCATAAAACAAAACCTCTCCTCAATATCAGATCAGATAAGACTCTTCAGGACATTGTTTACAAGCTCGTACCTGGTCTGTTCAAAAATGAGATGAAACGAAGGCGGGATTTTTACGCGGAGCATCCATCAGTTGATGCTACTAATGGTTCTAATGAAGACAGAGGAGAAGTGGCAGATGAAGACAAGAGAATCATTGCTGATGATGAGATCATCAGTCTGTCCATTGAGTTTTTTGATCAAAACAAGTTTGATAGTAAAGATGGAGAAGAAAAGGATACCACAAAAGAGGTGAATGTAAAGCGGTACTTACAATGCCCTGCAGCTATGACAGTAATGCATCTCAGAAAATTTCTCAGAAGTAAAATGGATATTCCCTGTACCTTTCAGATTGAAGTTATGTATGAAGATGAGCCATTGAAAGATTATTATACTCTCATGGATATTGCTTATATCTACACATGGAGAAGGAATGGGCCCTTGCCATTAAAGTACAGAGTTCGGCCTGGTTGCAAAAAAATGAAGTTGAGCAGCCCGAGGGATGAAATGACCGGTGGCAGAAGGCCTGATACAGAAAGTGATTCCAGCAGTGATAAACCGAACAGCCCGACTGCTGCTGCCGCCCCCTCGACATCCTCTTCACTGCCCAGCCCAAGCACCCCTGTCCAGTCTCCACATCCCAACTTCCCCCATATCTCCACTGTTAATGGAGTCTCTGCCAAAGTGGGCCACAATGGCCAAACTCCGTTCAGCAGCAAAGTCTGCAAAACCTCTCATAATGGTTCCAACTCTCTTGGGTGACTTGCTTATGGATGCCAAAGCCATCAATCCCATACAAACAGAGCTGTGATGTAGATGCTTTCTTTATAAACCACCTCTTCAATTTTTTATATCATTTTTAAATATATTTGTTTTGTCACCATGTGTGAAAACTTTGTAACACAGCATTGTTTGTGTTATATTTTGTATTAATTGCATAACTAACATTGTGAAGAGTACTGGAGGGAAACTCTGCAAGAAGGAGAATGTATCTAGGTGTTTTTATAAAATCTGTCTTGTTCATTTAGATTAGAACATATGTATATAAATCATTTCCTTGTTCATGAAGTCTCCA

Function

symbol description
bmi1b Predicted to enable promoter-specific chromatin binding activity. Acts upstream of or within cerebellum development. Predicted to be located in nucleus. Predicted to be part of PRC1 complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Orthologous to several human genes including COMMD3-BMI1 (COMMD3-BMI1 readthrough).
bmi1 Enables RING-like zinc finger domain binding activity; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in several processes, including histone H2A-K119 monoubiquitination; negative regulation of macromolecule metabolic process; and positive regulation of ubiquitin-protein transferase activity. Located in cytosol and nuclear body. Part of PRC1 complex. Implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Biomarker of esophagus squamous cell carcinoma and pancreatic ductal carcinoma.

GO:

id name namespace
GO:0016569 covalent chromatin modification biological_process

KEGG:

id description
K11459 PCGF4, BMI1; polycomb group RING finger protein 4

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000004_07164273_07167923.mRNA True 1555 mRNA 0.42 11 7164273 7168236

Neighbor

gene id symbol gene type direction distance location
CI01000004_07084569_07087489 KLHL40A coding upstream 76175 7084379 ~ 7088098 (+)
CI01000004_07075959_07081717 HHATL, HHATLA coding upstream 82432 7074308 ~ 7081841 (+)
CI01000004_07043037_07053182 PLCD1B coding upstream 110532 7042393 ~ 7053741 (+)
CI01000004_06989955_07000066 NA coding upstream 164040 6989562 ~ 7000233 (+)
CI01000004_06973330_06975283 NA coding upstream 188458 6972779 ~ 6975815 (+)
CI01000004_07196152_07199384 NEBL coding downstream 27916 7196152 ~ 7199414 (+)
CI01000004_07249855_07250697 NRN1B coding downstream 81355 7249591 ~ 7251433 (+)
CI01000004_07254370_07254880 LYRM4 coding downstream 86134 7254370 ~ 7255602 (+)
CI01000004_07262498_07264843 RPP40 coding downstream 94037 7262273 ~ 7265593 (+)
CI01000004_07306344_07318193 OXSR1B, OXSR1, OXSR1A coding downstream 138021 7306257 ~ 7318449 (+)
G28405 NA non-coding upstream 13786 7149337 ~ 7150487 (+)
G28583 NA non-coding upstream 26043 7137566 ~ 7138230 (+)
G28598 NA non-coding upstream 27113 7136504 ~ 7137160 (+)
G28596 NA non-coding upstream 29330 7134743 ~ 7134943 (+)
G28595 NA non-coding upstream 29585 7134475 ~ 7134688 (+)
G28606 NA non-coding downstream 26813 7195049 ~ 7195652 (+)
G28634 NA non-coding downstream 80312 7248548 ~ 7248777 (+)
G28406 NA non-coding downstream 121405 7289641 ~ 7295398 (+)
G28647 NA non-coding downstream 128856 7297092 ~ 7297341 (+)
CI01000004_06571261_06572539 SEP15 other upstream 589852 6570771 ~ 6572667 (+)
G28302 NA other upstream 662186 6470028 ~ 6502087 (+)
G28165 NA other upstream 1431272 5732589 ~ 5733001 (+)
G27805 NA other upstream 1790470 5372825 ~ 5373803 (+)
CI01000004_03550525_03552621 PTGER4C other upstream 3611827 3550329 ~ 3553423 (+)
CI01000004_07654234_07655677 MRPL34 other downstream 486536 7654234 ~ 7656383 (+)
CI01000004_08414451_08436256 NA other downstream 1265469 8414316 ~ 8439933 (+)
G28859 NA other downstream 1430999 8599235 ~ 8599603 (+)
CI01000004_08976512_08980033 TTPA other downstream 1808202 8976254 ~ 8980984 (+)
G30797 NA other downstream 3329140 10497376 ~ 10497788 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00019786 bmi1 coding CM030124.1 CM030124.1 44444891 ~ 44453292 (+)