Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_007651 |
| gene name | csf1ra |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007125.7 |
| NCBI id | CM002898.2 |
| chromosome length | 52660232 |
| location | 3143337 ~ 3180947 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| csf1ra | Predicted to enable macrophage colony-stimulating factor receptor activity. Acts upstream of or within several processes, including immune response in brain or nervous system; macrophage chemotaxis; and myeloid leukocyte differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of CSF1-CSF1R complex and receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including hematopoietic cell; neural crest cell; osteoclast; pigment cell; and rostral blood island. Used to study CSF1R-related brain malformation and osteopetrosis. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor). |
| id | name | namespace |
|---|---|---|
| GO:2001204 | regulation of osteoclast development | biological_process |
| GO:0002244 | hematopoietic progenitor cell differentiation | biological_process |
| GO:0019221 | cytokine-mediated signaling pathway | biological_process |
| GO:0045087 | innate immune response | biological_process |
| GO:0036035 | osteoclast development | biological_process |
| GO:0097324 | melanocyte migration | biological_process |
| GO:0033674 | positive regulation of kinase activity | biological_process |
| GO:0006954 | inflammatory response | biological_process |
| GO:0050936 | xanthophore differentiation | biological_process |
| GO:0048246 | macrophage chemotaxis | biological_process |
| GO:0007275 | multicellular organism development | biological_process |
| GO:0042481 | regulation of odontogenesis | biological_process |
| GO:0002376 | immune system process | biological_process |
| GO:0006468 | protein phosphorylation | biological_process |
| GO:0002383 | immune response in brain or nervous system | biological_process |
| GO:0014004 | microglia differentiation | biological_process |
| GO:0010759 | positive regulation of macrophage chemotaxis | biological_process |
| GO:0043473 | pigmentation | biological_process |
| GO:0048066 | developmental pigmentation | biological_process |
| GO:0048070 | regulation of developmental pigmentation | biological_process |
| GO:0030316 | osteoclast differentiation | biological_process |
| GO:0030318 | melanocyte differentiation | biological_process |
| GO:0016310 | phosphorylation | biological_process |
| GO:0061075 | positive regulation of neural retina development | biological_process |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | biological_process |
| GO:1990682 | CSF1-CSF1R complex | cellular_component |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0005887 | integral component of plasma membrane | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0043235 | receptor complex | cellular_component |
| GO:0016740 | transferase activity | molecular_function |
| GO:0005524 | ATP binding | molecular_function |
| GO:0000166 | nucleotide binding | molecular_function |
| GO:0019955 | cytokine binding | molecular_function |
| GO:0004672 | protein kinase activity | molecular_function |
| GO:0016301 | kinase activity | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | molecular_function |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | molecular_function |
| GO:0005011 | macrophage colony-stimulating factor receptor activity | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-001205-1 | Predicted to enable macrophage colony-stimulating factor receptor activity. Acts upstream of or within several processes, including immune response in brain or nervous system; macrophage chemotaxis; and myeloid leukocyte differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of CSF1-CSF1R complex and receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including hematopoietic cell; neural crest cell; osteoclast; pigment cell; and rostral blood island. Used to study CSF1R-related brain malformation and osteopetrosis. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor). |
| ensembl_id | ENSDARG00000102986 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00015018 | False | 3459 | mRNA | 0.48 | 20 | 3143337 | 3174570 |
| TCONS_00015019 | False | 3522 | mRNA | 0.49 | 21 | 3143421 | 3180947 |
| TCONS_00015020 | False | 3004 | mRNA | 0.51 | 20 | 3143901 | 3180841 |
| TCONS_00015021 | True | 2788 | lncRNA | 0.51 | 18 | 3144732 | 3174559 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_007650 | si:zfos-1069f5.1 | coding | downstream | 8501 | 3123517 ~ 3134836 (-) |
| XLOC_007649 | slc35a4 | coding | downstream | 71699 | 3062608 ~ 3071638 (-) |
| XLOC_007648 | ndst1a | coding | downstream | 111321 | 2986680 ~ 3032016 (-) |
| XLOC_007647 | bicc2 | coding | downstream | 163459 | 2941797 ~ 2979878 (-) |
| XLOC_007645 | spock1 | coding | downstream | 210071 | 2661646 ~ 2933266 (-) |
| XLOC_007652 | pdgfrb | coding | upstream | 5538 | 3186485 ~ 3268155 (-) |
| XLOC_007653 | CABZ01073834.1 | coding | upstream | 144920 | 3325867 ~ 3359054 (-) |
| XLOC_007654 | NA | coding | upstream | 181847 | 3362794 ~ 3381303 (-) |
| XLOC_007655 | PIGG | coding | upstream | 536798 | 3717745 ~ 3944017 (-) |
| XLOC_007656 | snx25 | coding | upstream | 779594 | 3960541 ~ 4044545 (-) |
| XLOC_007641 | CU855896.1 | misc | downstream | 735497 | 2407736 ~ 2407840 (-) |
| XLOC_007640 | CU855896.2 | misc | downstream | 735906 | 2407328 ~ 2407431 (-) |
| XLOC_007639 | CU855896.3 | misc | downstream | 736265 | 2406945 ~ 2407072 (-) |
| XLOC_007646 | NA | non-coding | downstream | 290082 | 2851570 ~ 2853255 (-) |
| XLOC_007642 | NA | non-coding | downstream | 622440 | 2511851 ~ 2520897 (-) |
| XLOC_007625 | NA | non-coding | downstream | 1269290 | 1868374 ~ 1874047 (-) |
| XLOC_007624 | NA | non-coding | downstream | 1281328 | 1861358 ~ 1862009 (-) |
| XLOC_007623 | NA | non-coding | downstream | 1303435 | 1807336 ~ 1839902 (-) |
| XLOC_007660 | BX088718.2 | non-coding | upstream | 979908 | 4160855 ~ 4163421 (-) |
| XLOC_007663 | NA | non-coding | upstream | 1106306 | 4287253 ~ 4287995 (-) |
| XLOC_007666 | NA | non-coding | upstream | 1415556 | 4596503 ~ 4599936 (-) |
