XLOC_008220 (p2ry12)


Basic Information

Item Value
gene id XLOC_008220
gene name p2ry12
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 1116664 ~ 1120421 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00016584
TTTGCAAAACAGCTCAGCGCACTGGCTCTGGGGGTCTTTCTGAGGCTGtgcaaaaaaatgttcatgggcatcatggtggtgcagttTGATTGCCTctctgcaagaaggttgctggttcaagcctcgactggGACTTCATTACTTCACCCAGCAGGACTCATCAATGGAGCAAACAACGCAGCTCAGCTTCTCCAACAGCAGCGTCTCCAACAGTTCATCCTGTTCTCGAGACGGCGCTCTGAAAACCATCGTCTTCCCCGTCCTCTACTCCATCCTCCTCATCCTGGGATTATCCCTGAACGCTCTGGCGGCTTGGGTTTTCCTCCGGATCCCCAGCAAATCCCACTTCATCATCTACCTGAAGAACATCGTGGTGGCCGACATCATCATGACCCTCACATTCCCCTTTAAAATATTATCCGATGCCAATGTAGCGTCCGTGGGCATCCGCATTTTTGTGTGCCGCGTGTCCTCCGTGCTCTTCTACCTCACCATGTACATCAGCATCCTGTTCTTCGGTTTGATCAGCATCGATCGCTGCAGAAAAACCATGTGGCCGTTCGTAGGCACCAACCCCAAACGTCTACTGCACAGAAAACTGCTTTCGGGAGTCATCTGGACGTCTCTCCTGGCTCTTTCGCTCCCAAATGTAATCCTGACCAGTCGTCCGAATATTGGAGAGCGCTTCAAATGCAGCGATCTCAAAACTGAGCTCGGACTGCAGTGGCATGAGGTGGTCAATCATATATGCCAGGTCATCTTTTGGGGAAACCTTATAATCGTGATCATATGCTACACGCTTATTTCCAGAGAGCTCTACAAGTCGTACGCCCGCACGAGGTCTCCGCGTGGGACGCAAAGCAAGAAGAAACACATCCAGGTTAATGTGTTCCTGGTGTTGGCcgtgtttttcatttgttttgtgccGTTTCACTTCGCGCGAGTGCCCTACACCATCAGCCAGACGCGCGCCCTCCTGTTCAGCTGCCCGCAGAAGCTGTTTTTCTTCAAGCTGAAGGAGAGCACGCTGTGGCTGTCCTCCCTCAATTCTGTGCTGGATCCGCTCATCTACTTCTTCCTCTGCAAGTCCTTCAGGTCGTCGCTGTTTAATGTGATGCGATTGGCTCCGGGACGCTGCAGGATCCTGAGGGAGCTCGGGACAGATTCGGCCGGCGATCAACAGGGAAACGCACTGACATGATGGACAAAACACGGACACACACATGGGAAAAACACTGGGGCTTGTTCTGTAAACATGCAATTATACAATGGGCAAGTGTTTTTCAACCACAGATACACTATCAATCAGAGGTTGATGTGTTCTTAAAGGTCCTGttgaattaaaatagaaaaatgtcGATGTTACGCTGC
>TCONS_00016585
ttgttattgtttaactCCCTCAAAACAGTCTTAGGACTCATCATTTCATTATGCATTCTTTCATTCAGGACTTCATTACTTCACCCAGCAGGACTCATCAATGGAGCAAACAACGCAGCTCAGCTTCTCCAACAGCAGCGTCTCCAACAGTTCATCCTGTTCTCGAGACGGCGCTCTGAAAACCATCGTCTTCCCCGTCCTCTACTCCATCCTCCTCATCCTGGGATTATCCCTGAACGCTCTGGCGGCTTGGGTTTTCCTCCGGATCCCCAGCAAATCCCACTTCATCATCTACCTGAAGAACATCGTGGTGGCCGACATCATCATGACCCTCACATTCCCCTTTAAAATATTATCCGATGCCAATGTAGCGTCCGTGGGCATCCGCATTTTTGTGTGCCGCGTGTCCTCCGTGCTCTTCTACCTCACCATGTACATCAGCATCCTGTTCTTCGGTTTGATCAGCATCGATCGCTGCAGAAAAACCATGTGGCCGTTCGTAGGCACCAACCCCAAACGTCTACTGCACAGAAAACTGCTTTCGGGAGTCATCTGGACGTCTCTCCTGGCTCTTTCGCTCCCAAATGTAATCCTGACCAGTCGTCCGAATATTGGAGAGCGCTTCAAATGCAGCGATCTCAAAACTGAGCTCGGACTGCAGTGGCATGAGGTGGTCAATCATATATGCCAGGTCATCTTTTGGGGAAACCTTATAATCGTGATCATATGCTACACGCTTATTTCCAGAGAGCTCTACAAGTCGTACGCCCGCACGAGGTCTCCGCGTGGGACGCAAAGCAAGAAGAAACACATCCAGGTTAATGTGTTCCTGGTGTTGGCcgtgtttttcatttgttttgtgccGTTTCACTTCGCGCGAGTGCCCTACACCATCAGCCAGACGCGCGCCCTCCTGTTCAGCTGCCCGCAGAAGCTGTTTTTCTTCAAGCTGAAGGAGAGCACGCTGTGGCTGTCCTCCCTCAATTCTGTGCTGGATCCGCTCATCTACTTCTTCCTCTGCAAGTCCTTCAGGTCGTCGCTGTTTAATGTGATGCGATTGGCTCCGGGACGCTGCAGGATCCTGAGGGAGCTCGGGACAGATTCGGCCGGCGATCAACAGGGAAACGCACTGACATGATGGACAAAACACGGACACACACATGGGAAAAACACTGGGGCTTGTTCTGTAAACATGCAATTATACAATGGGCAAGTGTTTTTCAACCACAGATACACTATCAATCAGAGGTTGATGTGTTCTTAAAGGTCCTGttgaattaaaatagaaaaatgtcGATGTTACGCTGC

Function

symbol description
p2ry12 Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within microglial cell activation. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in asthma; cerebrovascular disease; peripheral artery disease; platelet-type bleeding disorder 8; and type 2 diabetes mellitus. Orthologous to human P2RY12 (purinergic receptor P2Y12).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0001774 microglial cell activation biological_process
GO:0007596 blood coagulation biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0045028 G protein-coupled purinergic nucleotide receptor activity molecular_function

KEGG:

id description
ko04611 Platelet activation
ko04030 G protein-coupled receptors

ZFIN:

id description
ZDB-GENE-110208-4 Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within microglial cell activation. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in asthma; cerebrovascular disease; peripheral artery disease; platelet-type bleeding disorder 8; and type 2 diabetes mellitus. Orthologous to human P2RY12 (purinergic receptor P2Y12).

Ensembl:

ensembl_id ENSDARG00000069945

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00016584 False 1371 mRNA 0.51 3 1116664 1120421
TCONS_00016585 True 1308 mRNA 0.50 1 1119114 1120421

Neighbor

gene id symbol gene type direction distance location
XLOC_008219 igsf10 coding upstream 9556 1086656 ~ 1107108 (+)
XLOC_008218 CU571333.1 coding upstream 37560 1078989 ~ 1079104 (+)
XLOC_008217 znf1007 coding upstream 123231 983741 ~ 993433 (+)
XLOC_008216 alox5b.2 coding upstream 140311 963292 ~ 976353 (+)
XLOC_008215 si:dkey-77f5.10 coding upstream 174891 934660 ~ 941773 (+)
XLOC_008221 p2ry13 coding downstream 14449 1134870 ~ 1142663 (+)
XLOC_008222 mlf1 coding downstream 27653 1148074 ~ 1162658 (+)
XLOC_008223 gfm1 coding downstream 46698 1167119 ~ 1195012 (+)
XLOC_008224 mfsd1 coding downstream 78986 1199407 ~ 1220123 (+)
XLOC_008225 NA coding downstream 101396 1221817 ~ 1234693 (+)
XLOC_008463 BX663520.1 misc downstream 20131770 21252191 ~ 21252282 (+)
XLOC_008206 NA non-coding upstream 348229 768181 ~ 768435 (+)
XLOC_008204 NA non-coding upstream 447220 658362 ~ 669444 (+)
XLOC_008200 NA non-coding upstream 568783 546153 ~ 547881 (+)
XLOC_008197 NA non-coding upstream 616841 497208 ~ 499823 (+)
XLOC_008229 dre-mir-15c non-coding downstream 423265 1543686 ~ 1543768 (+)
XLOC_008230 dre-mir-16a non-coding downstream 423436 1543857 ~ 1543943 (+)
XLOC_008232 NA non-coding downstream 572776 1693197 ~ 1718629 (+)
XLOC_008236 CU638704.1 non-coding downstream 753237 1873658 ~ 1873778 (+)

Expression


Co-expression Network