RNA id: TCONS_00012192


Basic Information

Item Value
RNA id TCONS_00012192
length 2318
RNA type mRNA
GC content 0.47
exon number 20
gene id XLOC_006203
representative False

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 42602406 ~ 42617639 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence

GTTATTCGCGCCTGAACTTCTGCGGGTGTGCTGTAGGACTGAATGAGTTGATGATGGCGGGAGTCATCCGCAGACTCGACGAGACTGTAGTGAACCGCATCGCAGCCGGAGAGATTATCCAGCGGCCTGCCAATGCTATCAAAGAGATGATGGAGAACTGTTTGGATGCAAAGTCTACGAACATCCAGATAACAGTGAAAGAGGGCGGACTGAAACTCATCCTTATTCAGGACAATGGCACTGGAATTAGAaaagatgaTATGGAAATAGTCTGTGAGCGTTTTACGACCAGCAAGCTGCAGTCTTTTGAAGATTTGTCATCCATCGCAACATACGGATTCAGAGGAGAAGCCCTCGCCAGTATAAGTCATGTAGCTCACGTCACCATCACCACAAAAACAGCAGATGCTAAATGTGCTTAcagGGCCAATTACTGTGATGGGAAACTAAAATCTCCACCCAAACCCTGTGCTGGAAACCAGGGGACACTGATTTCTGTAGAGGATCTGTTTTATAATGTGTCTACGCGACGGAAAGCCCTAAAGAGCCCCAGTGAGGAATATTCCAGAATCGTCGAGGTTGTGAGCAGATACGCCATTCACAACTCTGGGAAAAGTTTTTCTGTCAAGAAGCAAGGTGAGATGGTTGCAGATGTGAAGACTCTCCCAAACGCCTCTGTGCTGGACAACATCCGTGTGGTGTTTGGAGTCGCAGTTAGCAGggAGCTGATTGAAGTTGAATGCGAGGATCAgaaatttgcttttaaagtgaagGGCTACATCTCCAATGCTAACTACTCTGTCAAGAAATGCATCCTTATCCTTTTTATCAATCATCGATTGGTGGAGTCTAGTGCCTTGAAGAAAGCAATTGAGACCGTCTACACCGCTTATCTTCCCAAAAACACTCATCCTTTTCTTTATCTCAGTTTAGAGATTGCTCCTCAAAACATTGATGTAAACGTTCACCCGACAAAACATGAGGTGCACTTCCTGCACGAGGACTCCATCATCGAGAGCATTCAGAAGCACATCGAGAGTAAACTCCTCGGCTCCAATTCCTCTCGCACGTACTTCACACAGACTCTACTTCCGGGACTTTCAGCATCTGCAAGCGTGGCAAAAGCTTCTAGTTCCTCAGCAGATTCCCAGGAGCGAGTTTACGCCCATCAGATGGTCCGCACTGACAGTAAAGCCCAGAAGCTTGATGCATTTCTCCAGCCATCAGCCTCATCTTCATCAACTGCTGCtcaaagaaagacagaaaaaaccTCCAGCACGTCAACTGCTGTACAAGACTTGGTGGAGCTGGACGACGCAGAGCTGCTGACAGCTGCTGATGTGGAGCCGTGTGGCGGAAAGGATCCTCAGACTGATGCTCAACCTCCTGGTGATGAAGCACCACCAAGgaaaaGGCCTCATGTTGAGGAGGTGAAGGAGGATTTGACAGCTGCTTCTCTTCCCAGGAGACGAATCGTTAAACTGACCAGCATAAAGGAGCTTCGGGACCAGATTGAGCTGCAAACTCACAAAGGTTTACAGGAGCTGCTGCAGAATCACTCATTTGTAGGTTCAGTCAGTCCTCAGTGGACTTTGGTGCAGCACCAGACCAAACTCTACCTGCTCAATACAACCAAACTCAGTCAGGAGCTGTTTTATCAAATTTTAGTCTACGACTTTGGTAACTTCGGCGTTCTTCGATTGTCGAATCCAGCGCCGCTCTATGATCTGGCCATGTTGGCTCTGGATTCAGAGGAAAGTGGATGGACAGAGGAGGATGGTCCGAAAGAAGGACTGGCCCAGTATATTGTGGATTTCCTTAAGCAGAAAGCAGAAATGCTGGAAGAATACTTTTCCTTGGAAATAGATGCAGAGGGAAACCTGACAGGTCTGCCAATGCTGTTGGATAATTACACTCCTGCCATGGAGGGACTGCCAATGTTCATTTTGCGTTTAGCCACTGAGGTGAACTGGGATAAAGAAAAGGAGTGTTTCCGTGAATTCAGTGTTGAATGCAGTCATTTCTACTCCATAAGGAAAAGCTACACACTGGAGGCAGACGCAGATGAGCCACAGGATGCTGAGATGAGCTGGCAGTGGAAGGTGGAGCATGTGCTTTTCAAAGCTTTGCGCTCTCTCTTCAGTCCTGCCAAACACTTGAGTGAAGACGGCAGTGTCCTGCAGATCGCCAGCCTGCCTGACCTCTACAAAGTGTTTGAAAGATGCTGAACCCCAGCACTGTCTAATCGGTTTAATGCTTGCTCGGTGAGCTTTTATAAATGTTTGTACtgtgaatgaataaaaagtctatatttttGA

Function

GO:

id name namespace
GO:0006298 mismatch repair biological_process
GO:0043060 meiotic metaphase I plate congression biological_process
GO:0007283 spermatogenesis biological_process
GO:0007059 chromosome segregation biological_process
GO:0051026 chiasma assembly biological_process
GO:0007141 male meiosis I biological_process
GO:0032300 mismatch repair complex cellular_component
GO:0032389 MutLalpha complex cellular_component
GO:0005712 chiasma cellular_component
GO:0030983 mismatched DNA binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0016887 ATPase activity molecular_function

KEGG:

id description
ko03430 Mismatch repair
ko03460 Fanconi anemia pathway
ko05200 Pathways in cancer
ko05210 Colorectal cancer
ko05226 Gastric cancer
ko05213 Endometrial cancer
ko01524 Platinum drug resistance
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-040426-1600 Predicted to enable ATP hydrolysis activity. Acts upstream of or within meiosis I and spermatogenesis. Predicted to be located in nucleus. Predicted to be part of MutLalpha complex. Is expressed in testis. Human ortholog(s) of this gene implicated in Lynch syndrome (multiple); gastrointestinal system cancer (multiple); lung cancer; mismatch repair cancer syndrome; and sporadic breast cancer. Orthologous to human MLH1 (mutL homolog 1).

Ensembl:

ensembl_id ENSDART00000133388

JBrowse2

Neighbor

RNA id RNA type direction distance location representative gene id
TCONS_00012191 lncRNA upstream 50972 42543960 ~ 42551434 (+) True XLOC_006202
TCONS_00013669 lncRNA upstream 739375 41859776 ~ 41863031 (+) False XLOC_006194
TCONS_00013670 lncRNA upstream 739375 41859778 ~ 41863031 (+) True XLOC_006194
TCONS_00013415 lncRNA upstream 740320 41859004 ~ 41862086 (+) False XLOC_006194
TCONS_00013414 lncRNA upstream 740399 41859004 ~ 41862007 (+) False XLOC_006194
TCONS_00013416 lncRNA downstream 201706 42819345 ~ 42819715 (+) True XLOC_006206
TCONS_00013671 lncRNA downstream 973128 43590767 ~ 43610001 (+) True XLOC_006210
TCONS_00012204 lncRNA downstream 1032754 43650393 ~ 43659337 (+) False XLOC_006211
TCONS_00012206 lncRNA downstream 1038877 43656516 ~ 43659337 (+) True XLOC_006211
TCONS_00013417 lncRNA downstream 1236981 43854620 ~ 43855787 (+) True XLOC_006212
TCONS_00012190 mRNA upstream 130346 42406883 ~ 42472060 (+) True XLOC_006201
TCONS_00012189 mRNA upstream 252246 42309688 ~ 42350160 (+) True XLOC_006200
TCONS_00012188 mRNA upstream 336821 42245221 ~ 42265585 (+) True XLOC_006199
TCONS_00012187 mRNA upstream 458769 42124566 ~ 42143637 (+) True XLOC_006198
TCONS_00012185 mRNA upstream 585927 42011287 ~ 42016479 (+) True XLOC_006196
TCONS_00012194 mRNA downstream 58563 42676202 ~ 42679041 (+) True XLOC_006204
TCONS_00012195 mRNA downstream 144587 42762226 ~ 43011856 (+) False XLOC_006205
TCONS_00012196 mRNA downstream 240589 42858228 ~ 42994216 (+) True XLOC_006205
TCONS_00012197 mRNA downstream 432923 43050562 ~ 43213012 (+) True XLOC_006207
TCONS_00012198 mRNA downstream 630297 43247936 ~ 43325720 (+) False XLOC_006208
TCONS_00012186 other upstream 560064 42042226 ~ 42042342 (+) True XLOC_006197
TCONS_00012184 other upstream 583458 42011285 ~ 42018948 (+) False XLOC_006196
TCONS_00012162 other upstream 2274169 40327562 ~ 40328237 (+) True XLOC_006179
TCONS_00012159 other upstream 2632941 39969349 ~ 39969465 (+) True XLOC_006177
TCONS_00012137 other upstream 4324425 38226157 ~ 38277981 (+) False XLOC_006165
TCONS_00012203 other downstream 1022320 43639959 ~ 43656324 (+) False XLOC_006211
TCONS_00012209 other downstream 1483206 44100845 ~ 44100965 (+) True XLOC_006215
TCONS_00012210 other downstream 1766638 44384277 ~ 44384393 (+) True XLOC_006218
TCONS_00012213 other downstream 2247955 44865594 ~ 44865710 (+) True XLOC_006223
TCONS_00012215 other downstream 2714566 45332205 ~ 45336705 (+) True XLOC_006226

Expression Profile

//

Homologous

species RNA id representative length rna type GC content exon number chromosome id location
grasscarp (Ctenopharyngodon idella) CI01180000_07655737_07662839.mRNA True 3077 mRNA 0.44 19 CI01180000 7654823 ~ 7662932 (+)