XLOC_015972 (klf2b)


Basic Information

Item Value
gene id XLOC_015972
gene name klf2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 55665095 ~ 55673225 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031645
GAGAGCGCACTGTGCCTTATATATAGACTATCTTTGGGAACTCTGAACGCGGTTTCCACCGCGCACACAATTGGTCTAGGAGCCGTATTTATTAAGTAGGAGGCGCTCCTGCCGGGCAAACTTTGTTCATGACTGTGGAAGTTCACTCGAGGAAAAAGCGCGCAGAAGTTTGACATCTCTTCAGGAGCAAGTGCATTAATACTGAATACACACCGAGCACGCGTGGACATGGCTTTACCTTGCCTTTTGCCTTCGATTTCAACGTTTGCAAACCAGAAGGAGAAGCTCTGGGAGGATagaTGGAAGATTGAGGAGCACAAACCACTGAACGCCAGCTGCCCTCCGCTCAACGTGGCACTGAACACAGACACTTGTCGAGGCCGTAAGGATGACGAGGATCTCAGCAATTATTTAGACCTGGAGTTTATCCTGGCCAACACCACGGGCCCTCTGGAGGCCGGAGCCGAGTTCATCTCCCACTCCGAGCCATGCGGCATGTACTCCACTGCAGTTTACTCATCTCCAGAAGCACCTCCACCATACGGCCTCATGGCAGAGCTCCTGCGATCTGATGTAGACTCCACGTATGACACCACAGTGCAGGGGAGATTCCTGCTCAACTCCAGCGGCTTCCCCAGACAGGAGTTTCCTGAAATCAAAGTGGAGCCGCCGATGGATGGCTACGGTCCGGTGATAGGCATGGTGCCACAAACCTGCCAAAAAATCAAGCAGGAAGGCAACGTTTCATGCATGATGTCTTTCGAGCAGCCCAGACTAGCAGTTTCTCCGCAGGCCACCGGGAAtatgactcctccgctgagtcctGACGACTCCCACCTCCGTCAAACGACATATACACAGAGCTACCATCACTCTCCTCCGGCGTATCCGCAGGTGCCAATGCAGTTCACCGCGCCACACCAGTTTGCCATGTATGAGGAGGCAATGGGGATGCAACCCAGCATGCAGCGGGCTCTTCTCACTCCTCCGTCCTCTCCGTTAGAGCTAATGGAGTCTAAACCCAAGCGAGGGCGACGCACCTGGCCGAGGAAGCGCATGGCgacacatacatgcacatacgCCGGCTGCGGGAAGACGTACACCAAAAGCTCCCATTTAAAAGCGCATCACCGCACTCACACCGGTGAAAAACCATACCACTGCAACTGGGAGGGATGCGGATGGAAGTTCGCCCGTTCTGACGAGCTGACGCGTCACTTCCGTAAACACACGGGCCACCGGCCGTTCCAGTGCCACCTGTGTGAACGTGCCTTCTCCCGCTCCGACCACCTGGCGCTGCACATGAAGAGACACCTGTGAGGGCCGGATCCACCACAACTGCCTTATTTAATGactcttattatatatatatcatcatacTTTTATAACAAAGTAGCTGGTACTACATAGATCACGCAGAGCTCTTTTTAAGGCCTTTTTTTGGGGTTAAAAAGCATCCTGAAAGGCTGGTCCTACGAATCGGTGTCCAATCCGGAGACTGTTATGTTGAATTAACGATGCCACAACGAGTGCAAAGCCTGACGACTAGCAAACCAAAGTGGAAAATGCACAACGATGTTGACAATGTTTTGCTCGAAACTGCCATGCAACAAATGTGTTTCATTTTTACCAGGGCTGGGAGGATAAAATCATTATTGTGAATCAAGAAATGATTCCTACATTTTCTGAATGCATTGCGATTTCCTTTTGAATCGATTTGAAGCTTAGTTTTtaccaccagagggcactgtatGCTTTACACatacaatttaaatgtaaaacaattattaatacaAACATTTGTACATAAACTAGCCTAGACCTCTGTTAAAAGTTAACCTATAGtgcgtctgctgttaaaaactagcctagagcgccctctagtgttaaaaactagcctagagtactGTCTGGTGTTTACAAACTAGTCTAGAGCTTCATCTACTGTTCAAACCTAGCCTAGACCTCTGTTAAAGATTAACCTATAgtgcatctgctgttaaaaactagcatagagctgcctctggtgttaaaaactagcctcgagtgtcatctgctgtttgaaaactagcctagagtgcattCTTCTGCTCAAAACTAGCCTTGACCTCTGTTAAAATTAGCCTATAGtgcgtctgctgttaaaaactagcctagagcgccatttggtgttaaaaactagcctagagcgccctctgctgctCAAAACTAACCTAAACctctgttaaaaattagcctataTAGTGTCTggtgttaaacactagtctagactGCCCTctgatgttaaaaaaaactagcctagagtgcctttTGTTgcttaaaactagcctagacctcAGTTTAAAAATTAGCCTACAGTGCATCTgctgataaaaactagcctagagcgctctcaggtgttaaaaactagcctagagtgctgtctgcttcTCAAAAACTAGTCTAGACTTGATTCCTTTgcttaaaactagcctagacctcTGTTAAAAAATTAGCCTATAGTGCgtctgctgttacaaactagcccAGAACATCCTCTGGTGTTaaataactagcctagagcaccatctgttgctCAGAACTAACCTAGACctctgttaaaaattagcctttATTGCGTCtccggttaaaaactagcctagagcgccctctagtgttaaaaactagtctagagcgccctctgctgcaCAAAATTAGCCTAAACCTATGTTAAAATTAGACAAGAGTGCGtttgctggtaaaaactagcaaAGAGCGCCCTCTggtgttaaaatctagcctagagcacactgtggtgttaaaaactagCCAAGAGCGCCGTTtgcagttcaaaactagcctagattgcTGTTAAACATTAGTCTAGATCCCATATGCTGTTATAAACtcacctagagcgccatctgctgtcaaaaaactcacctagagcgccatctgctgttaaaaacggATCTTAGAATTGATTCCAGAGAGAATCGGGACGCAGTTAAAAATCTAACAATCGATTCATGAATAACAATACAATGATTTATCAATTCCAGCCctaattttttacatatttctttCCAAATGTTGGTAACGCTTTACAATAATGCTGCATTTAGTAAATGCATTGAGCAAAAAAAGTGTGTAATTTAGGTGCATTGGATCACACCAACAGATGCAACTTTTGTAAGTGTTAAAGGGACGGCTCACTCCAAAACTGAAGATGAcctccattgactttcatagtaattgttttttatcctatggaagtcagtggagaCCATCAagtagcattcttcaaaatatcttctgtagtgtttaacagatgaaaagagtgagtgaatgatgacagatgtAATTccttgtgtgaactatccctttaacgcaTGTTCCCTATTGTAAAACATTCCTCAAACGGCGGCACATTCAGTGTCCTCTTGTTCAATAGCACCGGATGCGCTGGGTCTTGAAGTCCTGGGTCTTTTTTTATATGATTGTGtacatacattttatattgtaagtactgtatttattgtaaatattaaactaaatttgAAT
>TCONS_00031646
ATGGCTTTACCTTGCCTTTTGCCTTCGATTTCAACGTTTGCAAACCAGAAGGAGAAGCTCTGGGAGGATagaTGGAAGATTGAGGAGCACAAACCACTGAACGCCAGCTGCCCTCCGCTCAACGTGGCACTGAACACAGACACTTGTCGAGGCCGTAAGGATGACGAGGATCTCAGCAATTATTTAGACCTGGAGTTTATCCTGGCCAACACCACGGGCCCTCTGGAGGCCGGAGCCGAGTTCATCTCCCACTCCGAGCCATGCGGCATGTACTCCACTGCAGTTTACTCATCTCCAGAAGCACCTCCACCATACGGCCTCATGGCAGAGCTCCTGCGATCTGATGTAGACTCCACGTATGACACCACAGTGCAGGGGAGATTCCTGCTCAACTCCAGCGGCTTCCCCAGACAGGAGTTTCCTGAAATCAAAGTGGAGCCGCCGATGGATGGCTACGGTCCGGTGATAGGCATGGTGCCACAAACCTGCCAAAAAATCAAGCAGGAAGGCAACGTTTCATGCATGATGTCTTTCGAGCAGCCCAGACTAGCAGTTTCTCCGCAGGCCACCGGGAAtatgactcctccgctgagtcctGACGACTCCCACCTCCGTCAAACGACATATACACAGAGCTACCATCACTCTCCTCCGGCGTATCCGCAGGTGCCAATGCAGTTCACCGCGCCACACCAGTTTGCCATGTATGAGGAGGCAATGGGGATGCAACCCAGCATGCAGCGGGCTCTTCTCACTCCTCCGTCCTCTCCGTTAGAGCTAATGGAGTCTAAACCCAAGCGAGGGCGACGCACCTGGCCGAGGAAGCGCATGGCgacacatacatgcacatacgCCGGCTGCGGGAAGACGTACACCAAAAGCTCCCATTTAAAAGCGCATCACCGCACTCACACCGGTGAAAAACCATACCACTGCAACTGGGAGGGATGCGGATGGAAGTTCGCCCGTTCTGACGAGCTGACGCGTCACTTCCGTAAACACACGGGCCACCGGCCGTTCCAGTGCCACCTGTGTGAACGTGCCTTCTCCCGCTCCGACCACCTGGCGCTGCACATGAAGAGACACCTGTGAGGGCCGGATCCACCACAACTGCCTTATTTAATGactcttattatatatatatcatcatacTTTTATAACAAAGTAGCTGGTACTACATAGATCACGCAGAGCTCTTTTTAAGGCCTTTTTTTGGGGTTAAAAAGCATCCTGAAAGGCTGGTCCTACGAATCGGTGTCCAATCCGGAGACTGTTATGTTGAATTAACGATGCCACAACGAGTGCAAAGCCTGACGACTAGCAAACCAAAGTGGAAAATGCACAACGATGTTGACAATGTTTTGCTCGAAACTGCCATGCAACAAATGTGTTTCATTTTTACCAGGGCTGGGAGGATAAAATCATTATTGTGAATCAAGAAATGATTCCTACATTTTCTGAATGCATTGCGATTTCCTTTTGAATCGATTTGAAGCTTAGTTTTtaccaccagagggcactgtatGCTTTACACatacaatttaaatgtaaaacaattattaatacaAACATTTGTACATAAACTAGCCTAGACCTCTGTTAAAAGTTAACCTATAGtgcgtctgctgttaaaaactagcctagagcgccctctagtgttaaaaactagcctagagtactGTCTGGTGTTTACAAACTAGTCTAGAGCTTCATCTACTGTTCAAACCTAGCCTAGACCTCTGTTAAAGATTAACCTATAgtgcatctgctgttaaaaactagcatagagctgcctctggtgttaaaaactagcctcgagtgtcatctgctgtttgaaaactagcctagagtgcattCTTCTGCTCAAAACTAGCCTTGACCTCTGTTAAAATTAGCCTATAGtgcgtctgctgttaaaaactagcctagagcgccatttggtgttaaaaactagcctagagcgccctctgctgctCAAAACTAACCTAAACctctgttaaaaattagcctataTAGTGTCTggtgttaaacactagtctagactGCCCTctgatgttaaaaaaaactagcctagagtgcctttTGTTgcttaaaactagcctagacctcAGTTTAAAAATTAGCCTACAGTGCATCTgctgataaaaactagcctagagcgctctcaggtgttaaaaactagcctagagtgctgtctgcttcTCAAAAACTAGTCTAGACTTGATTCCTTTgcttaaaactagcctagacctcTGTTAAAAAATTAGCCTATAGTGCgtctgctgttacaaactagcccAGAACATCCTCTGGTGTTaaataactagcctagagcaccatctgttgctCAGAACTAACCTAGACctctgttaaaaattagcctttATTGCGTCtccggttaaaaactagcctagagcgccctctagtgttaaaaactagtctagagcgccctctgctgcaCAAAATTAGCCTAAACCTATGTTAAAATTAGACAAGAGTGCGtttgctggtaaaaactagcaaAGAGCGCCCTCTggtgttaaaatctagcctagagcacactgtggtgttaaaaactagcctagagcgccttctgctgctcaaaactagcctagatttcTGTTAAAAATTAGCCAAGAGCGCCGTTtgcagttcaaaactagcctagattgcTGTTAAACATTAGTCTAGATCCCATATGCTGTTATAAACtcacctagagcgccatctgctgtcaaaaaactcacctagagcgccatctgctgttaaaaacggATCTTAGAATTGATTCCAGAGAGAATCGGGACGCAGTTAAAAATCTAACAATCGATTCATGAATAACAATACAATGATTTATCAATTCCAGCCctaattttttacatatttctttCCAAATGTTGGTAACGCTTTACAATAATGCTGCATTTAGTAAATGCATTGAGCAAAAAAAGTGTGTAATTTAGGTGCATTGGATCACACCAACAGATGCAACTTTTGTAAGTGTTAAAGGGACGGCTCACTCCAAAACTGAAGATGAcctccattgactttcatagtaattgttttttatcctatggaagtcagtggagaCCATCAagtagcattcttcaaaatatcttctgtagtgtttaacagatgaaaagagtgagtgaatgatgacagatgtAATTccttgtgtgaactatccctttaacgcaTGTTCCCTATTGTAAAACATTCCTCAAACGGCGGCACATTCAGTGTCCTCTTGTTCAATAGCACCGGATGCGCTGGGTCTTGAAGTCCTGGGTCTTTTTTTATATGATTGTGtacatacattttatattgtaagtactgtatttattgtaaatattaaactaaatttgAATATAAATACTCATGTGTGGTGTCGTTTGCCTGTCATGTTGGATGTGGCTTCTTCGCTGGTCTCTTATTATGGGCTGCTTTGAAGCGACTGGAAAGCAAAGTCCCCAGAAACGAGTGCTATTCTTGAACCCCCACTCAAGCTCACCGACTCGGGTATTATAGCGCAGACCAAGATGCTTTCCAGCTGCGTCAGGTCGAGGCCAGCAGCCTGTGGCTTCTGCCTATAAATACAAACACTGCATTTCCATAATTACAGAGAGAGAATTTAGATGCGTCTGGACGGCTCTGCTCAACATCTCAGACTCGCAGACATCAAAGACGCACCGCTGCAGCTTTGATCTGCAACCTGcaagataaacaataatgctgcatctgcatatttaattaaatactgcGGCAACTTCTACTTACCTGGGTTTGAGAGGACATActcaaaaaaaaactatttgagaTCTATATAtaggaaaaacacaaatatgattacatttatttacatatacagcACAGGTCAATAGGTTAAACACACCTACAGATGGTATGCTAttgctctttttttatatatagatgtactcaaatatatacacttaccggccactttattaggtacgccttatAAGTACTGGAtttgatccccttttgccttcagaactgccttaatccttcgtggcatagattcaacaaggtactggaaatattcctcatagattttactccgtattgacatgatagcatcacacagttgctgcagatttgtcggcttcacatccatgatgccaatcttccGTTCCACTACGAAgcacccaaaggtgctctattgcagCGGTTCCCAAACTTTacagcccacgacccccaaaataacaatgtcagtagCTCGCGACctccatttttcaaggtggttatactgtaaatatgtaaacgttgCAGACACTATAGACATGTATAAACataagcatattgacaacacaaaaatgcaacagtctattaaccatatattttttatagttgtttattaattacattttaatataaaatttaaaggctgatggctgagTTTTATTTGTaagttgttgtttctttaacacaactatcttctgtgggttctgaataaaatatggtaattcaaatagtttaataaaattaatttgagttttggaaatcactaagcgaccccttgtcattgtcccgcaACCCCATCCCCAgggggtcctgacccccactttgagaaccacttctctataggattgagctctggtgactgtggaggccatttgagtacagtgaactcattgtcatgttcaagaaaccagtctgagatcattcacgctttatgacatggtgcgttatcctgctgaagataggtacactgtggtcataaagggatggacatggtcagcaataatactcaggctgtggtgttgactcaatgctcaattggtactaatgagcccaaagtgtgccaagaaaacatcccccacaccattacaccaccaccaccagcctgaacggttgatacaaggcaggatggattcatgctttcatgttgatgccaaattctgacccgaccatccgaatgttacagcagaaatggagactagtcagagcaggcaacatttctccaatcttctattgtccagttttggtgagcctgtgtgaattgtagcctcagtttcctgttcttagctgacaggagtggcacccggtgtggtcttctgctgctgtagcccattcgcctcaaggttggacgtgttgtgtgttcagagatgctcttctgcagacctcagttgtaccGAGTGCTTATTTGATTAActcttgcctttctatcaactggaaccagtctggccattctcctctgacctctggcatcaacaaggcatttgcgcccacagaactgccgctcattggatatttcctccttttcagatcattctttgtaaaccctagatatggtagtgcgtaaaaatcccagtagatcagcggtttctgaaatactcagaccagcccttctggcaccaacaacagtgccaccttcaaagtcacttaaatcccctttcttccccattctgatgctcgctttgaactgcagcagatcatcttgaccatgtctacatgcctaaatgcattgagttgctgccatgtgattggctgattagaattttccattaacgagcagttggagcggtgtacctaataaagtggccggtgagtgtatacacagtaaaaataaaactaaagaatAAAAGTAATTAAGAATAAAAATGCAAAGTTCAAACGTGTAATAAAGCATAATCGCTGTCAGTTATCAAGAGTCACTAATAATATACGcctaaaaacatataaaataccTAAACTTTATTAGGACTACACAATTTTGTGAATAATTTTACTTCGATTATTTGATCTCtttacattc

Function

symbol description
klf2b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of mesodermal cell fate specification; regulation of ectodermal cell fate specification; and ventricular compact myocardium morphogenesis. Is expressed in several structures, including EVL; ectoderm; pectoral fin; presumptive ectoderm; and trunk vasculature. Orthologous to human KLF2 (Kruppel like factor 2).

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0003223 ventricular compact myocardium morphogenesis biological_process
GO:0042662 negative regulation of mesodermal cell fate specification biological_process
GO:0042665 regulation of ectodermal cell fate specification biological_process
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-011109-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of mesodermal cell fate specification; regulation of ectodermal cell fate specification; and ventricular compact myocardium morphogenesis. Is expressed in several structures, including EVL; ectoderm; pectoral fin; presumptive ectoderm; and trunk vasculature. Orthologous to human KLF2 (Kruppel like factor 2).

Ensembl:

ensembl_id ENSDARG00000040432

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031645 False 3543 mRNA 0.45 4 55665095 55670817
TCONS_00031646 True 5776 mRNA 0.43 3 55665323 55673225

Neighbor

gene id symbol gene type direction distance location
XLOC_015971 NA coding upstream 61530 55603128 ~ 55603565 (+)
XLOC_015970 ap1m1 coding upstream 172780 55429988 ~ 55492315 (+)
XLOC_015969 LPL coding upstream 274763 55365727 ~ 55390332 (+)
XLOC_015968 NA coding upstream 395805 55268020 ~ 55269290 (+)
XLOC_015967 cib3 coding upstream 398124 55249838 ~ 55266971 (+)
XLOC_015973 NA coding downstream 104597 55777822 ~ 55780037 (+)
XLOC_015974 NA coding downstream 109312 55782537 ~ 55784445 (+)
XLOC_015975 atcayb coding downstream 241474 55914699 ~ 55970970 (+)
XLOC_015976 nmrk2 coding downstream 309075 55982300 ~ 55990329 (+)
XLOC_015977 loxl5b coding downstream 338791 56012016 ~ 56041890 (+)
XLOC_015960 CABZ01050280.1 non-coding upstream 1217382 54430632 ~ 54447713 (+)
XLOC_015959 NA non-coding upstream 1237157 54425088 ~ 54427938 (+)
XLOC_015956 CU179656.2 non-coding upstream 1350886 54305610 ~ 54314209 (+)
XLOC_015978 NA non-coding downstream 451778 56125003 ~ 56130443 (+)
XLOC_015981 NA non-coding downstream 498868 56172093 ~ 56172528 (+)
XLOC_015983 NA non-coding downstream 651109 56324334 ~ 56335388 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000075_01159479_01160597 KLF2B coding CI01000075 null 1159479 ~ 1160663 (+)