XLOC_000220 (casp3a)


Basic Information

Item Value
gene id XLOC_000220
gene name casp3a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 17527342 ~ 17536307 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000370
ACTTGCCATATCGCCCGCATACACTTCCTGGACGCTGCTGAGGAACCGCTTTGTCATCGGAATCTTGCACATAATAAGGTGCTAACTAACAAGCGGATATTTTCGGTTCTCGGTTGATGTTTTTTTTGCACAGCTGTTGAAGGGTGACGTCTGCAGCTTCTCATTGGCTGGTGGTGCCAGTCAACAAACAAAGAATACACATCGGACATGCGGATACGGAGACTACTCTTTTTAAGAGCTGTTATAACACCTTAAACACCCACAGTTACACATATAACAGCTTTCAGGAGGAGAAGAAACCTGTTTACTGTTTAAAAGGGCTCGTTAAGCGGTTGGAGATGAACGGAGACTGTGTGGACGCAAAGCGTGTGGATACAACAGATGCTAGTAAGGATGGGGCATCTGCATCACAGCCCATGCAGGTTGATGCCAAGCCTCAATCCCATGCCTTCAGATACAGCTTGAACTACCCCAACATCGGCCACTgcatcatcatcaacaacaagAACTTTGATCGCAGGACAGGCATGAACCCACGCAATGGCACTGACGTAGATGCAGGAAATGTAATGAACGTGTTTCGAAAGCTTGGATACATTGTGAAAGTCTACAATGACCAGACAGTTGCGCAGATTATGCAGGTTTTAACAACAGTTGCCCATGACGATCACAGCCGCTGTGCttcattagtgtgtgtgttgCTCAGTCACGGCGATGAGGGGGTGTTTTTCGGCACTGATACATCTGTGGATCTCAAGTCTTTAACTAGTCTGTTCAGAGGAGACCGCTGCC
>TCONS_00000371
GCTGAGGAACCGCTTTGTCATCGGAATCTTGCACATAATAAGGTGCTAACTAACAAGCGGATATTTTCGGTTCTCGTGCTAGTAAGGATGGGGCATCTGCATCACAGCCCATGCAGGTTGATGCCAAGCCTCAATCCCATGCCTTCAGATACAGCTTGAACTACCCCAACATCGGCCACTgcatcatcatcaacaacaagAACTTTGATCGCAGGACAGGCATGAACCCACGCAATGGCACTGACGTAGATGCAGGAAATGTAATGAACGTGTTTCGAAAGCTTGGATACATTGTGAAAGTCTACAATGACCAGACAGTTGCGCAGATTATGCAGGTTTTAACAACAGTTGCCCATGACGATCACAGCCGCTGTGCttcattagtgtgtgtgttgCTCAGTCACGGCGATGAGGGGGTGTTTTTCGGCACTGATACATCTGTGGATCTCAAGTCTTTAACTAGTCTGTTCA
>TCONS_00000372
GCTGAGGAACCGCTTTGTCATCGGAATCTTGCACATAATAAGGTGCTAACTAACAAGCGGATATTTTCGGTTCTCGCTGTTGAAGGGTGACGTCTGCAGCTTCTCATTGGCTGGTGGTGCCAGTCAACAAACAAAGAATACACATCGGACATGCGGATACGGAGACTACTCTTTTTAAGAGCTGTTATAACACCTTAAACACCCACAGTTACACATATAACAGCTTTCAGGAGGAGAAGAAACCTGTTTACTGTTTAAAAGGGCTCGTTAAGCGGTTGGAGATGAACGGAGACTGTGTGGACGCAAAGCGTGTGGATACAACAGATGCTAGTAAGGATGGGGCATCTGCATCACAGCCCATGCAGGTTGATGCCAAGCCTCAATCCCATGCCTTCAGATACAGCTTGAACTACCCCAACATCGGCCACTgcatcatcatcaacaacaagAACTTTGATCGCAGGACAGGCATGAACCCACGCAATGGCACTGACGTAGATGCAGGAAATGTAATGAACGTGTTTCGAAAGCTTGGATACATTGTGAAAGTCTACAATGACCAGACAGTTGCGCAGATTATGCAGGTTTTAACAACAGTTGCCCATGACGATCACAGCCGCTGTGCttcattagtgtgtgtgttgCTCAGTCACGGCGATGAGGGGGTGTTTTTCGGCACTGATACATCTGTGGATCTCAAGTCTTTAACTAGTCTGTTCAGAGGAGACCGCTGCCCATCACTAGTGGGAAAGCCTAAACTGTTCTTTATTCAGGCTTGTCGAGGAACAGAACTGGATCCTGGTGTGGAAACTGACCACCCTGATCACCCTGACATCCCAGATGGTCGTGTAAGGATCCCAGTGGAGGCAGATTTCCTCTATGCATACTCTACTGTACCAGGTTATTACTCCTGGAGAAACACAATGACCGGCTCATGGTTCATTCAGTCACTTTGTGAAATGATGACAAAGTATGGCAGTGAACTGGAGCTCTTGCAGATCATGACCAGGGTCAACCATAAAGTAGCACTGGATTTTGAGTCCACCTCCAACATGCCGGGCTTTGATGCCAAGAAACAGATCCCCTGCATCGTCTCAATGCTCACCAAAGAGATGTACTTCACTCCTTAAAACCACCAGGGAATCTTTGAGAACGTCAGCAGCTGTTTTTGGTAGGTTTCACAAGTAGGATGTGCACTTTTAAGGGTTGGCTTTAGGAGTATAAGACCATTTCTTTACAGCAAAACTCTTCAGAACCACTGAAATATTAGCAGAACATTCTCAGTCTCAGGTTTATTGTGTTTTTCTAACAGTTATAAATGGTCTGTGCTTGCAAATAGGTGCTCAAACAGTTTTGTGTTCTTGTGACTTTATATGGTTTCACTTGCCTCTGTTCTTTCTATTcatgatgtaataataataatagtaatgaacaATCTTCAGAGGTAAGTGATGTTGGGATTTCTAGAGTTATAGTAATCGGGGACTTTCATAAGCATTAATATGCTATTGCACTGTTAAAAAGGGAATCATAAATGGGCATTGAATTAGTTAAATCAGTGATATTGGAGATGTATCTTAATCAAAGGGAGACCGCTGTGCCTATTTTAATGTGAAAAGCAAAGAGCAACAGTCAGAAATAACTATTGCCTAGTGCCTCTCTCTGAGCCATGTGAAGGGATTTTGATAAACCTTTTGAATAAATCTTTTTTACAGTTTTCCACGAGACACgataaatgcattatttacagaaatatttGGGGTTAAAGGAAAGTTCAACTCCCACCTCCTCAAAATACAGCTGTCACCAtgtactcacccttcacttatttcaaacctgtttgacttactttcttttattgaacaagaagatattttgaaaaatgttaaaaacaattgGCTtcctagtgtttgtttttcctactatggatgtcaatggttacccgtttccaacattcttcagattatCTTCTTTAGTTTTAAACAGAAGCAACTCGTAATATCTGGAACCACTAAAGGGTGAGATAATGTGCAATTGTTGGGTGGACAATCTGTTAATATCAACTTCAGCTTTGGACATTCTttccaaatctgtttgacttACGTTCTTACcgtgaacaaaaaagaagatattttgaaaaatgctggtacaGTGGACTTGATAGTATTTGttattcctactatggatgtcagtggttacccatttccaacattcttcagaatatcttcgtTAGTTTTAAACAGAAGAAAATCTAAATATCCGGAACCACTAAAGGGTGAGATAATGTGTCATTTTTATGTGAACAATTCGTTTATATCAACTTCAGCTGTGGACATtctttccaaacctgtttgacacTTTCTTCTCtggaacaaaagaagatattttgaaaaatgttagaatctGGTAGCAATTGgcttcatagtatttgtttttgttactatggatgtcaatagttacccatttccaacattcttcagaatatcttcttttgttttaaagAGAAGAAACTCTTAAATATTTGGAACCAGTAAAGGGTGAACAAACGTGTAATTTCTGTGTGAATGGTCCGTTTATATCATCGTATTTTACTAACaacgttaaaaaaaatctactaacATTTCTAGACTTAAAGTGGAAGTCTATTGGCTGTCAACAAATGTTTGTGGTCATTTGTATTTGATCTGGAGTGCTCTGTAATTTGTCCCCTTAAGATGATGATGAATGTCATTCATCTGTGAGAAATCATGTACACTTATTACTGCTGAGGTCACTGATACATTGTGTGTTTTCCTGATGCATGCGTACATAGAAAACAACATACCTTTTGTGTTTATTGTACAATCTTGGTTATAGTACATGTTAGTTTTTTTCTATGTAAAACCACCTTTGTATGTAATAAAACAGCTCTGCAGTAC
>TCONS_00000373
CCCAAATCTTATTTCAGGTTGATGTTTTTTTTGCACAGCTGTTGAAGGGTGACGTCTGCAGCTTCTCATTGGCTGGTGGTGCCAGTCAACAAACAAAGAATACACATCGGACATGCGGATACGGAGACTACTCTTTTTAAGAGCTGTTATAACACCTTAAACACCCACAGTTACACATATAACAGCTTTCAGGAGGAGAAGAAACCTGTTTACTGTTTAAAAGGGCTCGTTAAGCGGTTGGAGATGAACGGAGACTGTGTGGACGCAAAGCGTGTGGATACAACAGATGCTAGTAAGGATGGGGCATCTGCATCACAGCCCATGCAGGTTGATGCCAAGCCTCAATCCCATGCCTTCAGATACAGCTTGAACTACCCCAACATCGGCCACTgcatcatcatcaacaacaagAACTTTGATCGCAGGACAGGCATGAACCCACGCAATGGCACTGACGTAGATGCAGGAAATGTAATGAACGTGTTTCGAAAGCTTGGATACATTGTGAAAGTCTACAATGACCAGACAGTTGCGCAGATTATGCAGGTTTTAACAACAGTTGCCCATGACGATCACAGCCGCTGTGCttcattagtgtgtgtgttgCTCAGTCACGGCGATGAGGGGGTGTTTTTCGGCACTGATACATCTGTGGATCTCAAGTCTTTAACTAGTCTGTTCAGAGGAGACCGCTGCCCATCACTAGTGGGAAAGCCTAAACTGTTCTTTATTCAGGCTTGTCGAGGAACAGAACTGGATCCTGGTGTGGAAACTGACCACCCTGATCACCCTGACATCCCAGATGGTCGTGTAAGGATCCCAGTGGAGGCAGATTTCCTCTATGCATACTCTACTGTACCAG

Function

symbol description
casp3a Enables peptidase activity. Acts upstream of or within several processes, including cellular response to antibiotic; cellular response to retinoic acid; and regulation of collateral sprouting in absence of injury. Predicted to be active in cytoplasm. Is expressed in several structures, including axis; germ ring; gonad; gut; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP3 (caspase 3).

GO:

id name namespace
GO:0071300 cellular response to retinoic acid biological_process
GO:0006915 apoptotic process biological_process
GO:0030182 neuron differentiation biological_process
GO:0043065 positive regulation of apoptotic process biological_process
GO:0030216 keratinocyte differentiation biological_process
GO:0030218 erythrocyte differentiation biological_process
GO:0006508 proteolysis biological_process
GO:0071466 cellular response to xenobiotic stimulus biological_process
GO:0071236 cellular response to antibiotic biological_process
GO:0048696 regulation of collateral sprouting in absence of injury biological_process
GO:0005737 cytoplasm cellular_component
GO:0004197 cysteine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process molecular_function

KEGG:

id description
ko04215 Apoptosis - multiple species
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-011210-1 Enables peptidase activity. Acts upstream of or within several processes, including cellular response to antibiotic; cellular response to retinoic acid; and regulation of collateral sprouting in absence of injury. Predicted to be active in cytoplasm. Is expressed in several structures, including axis; germ ring; gonad; gut; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP3 (caspase 3).

Ensembl:

ensembl_id ENSDARG00000017905

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000370 False 792 mRNA 0.47 5 17527342 17531542
TCONS_00000371 False 471 mRNA 0.47 4 17527378 17531527
TCONS_00000372 False 2918 mRNA 0.39 7 17527378 17536307
TCONS_00000373 True 862 mRNA 0.47 5 17527931 17531812

Neighbor

gene id symbol gene type direction distance location
XLOC_000219 fat1a coding upstream 2420 17376922 ~ 17524922 (+)
XLOC_000218 CR377220.1 coding upstream 758533 16768683 ~ 16768809 (+)
XLOC_000217 NA coding upstream 853216 16672089 ~ 16674126 (+)
XLOC_000216 pcm1 coding upstream 873181 16621345 ~ 16654161 (+)
XLOC_000215 mtus1b coding upstream 907484 16548733 ~ 16619858 (+)
XLOC_000221 helt coding downstream 57085 17593392 ~ 17595045 (+)
XLOC_000222 slc25a4 coding downstream 140438 17676745 ~ 17679089 (+)
XLOC_000223 ankrd37 coding downstream 159119 17695426 ~ 17698773 (+)
XLOC_000224 CR774194.1 coding downstream 322073 17858380 ~ 17861928 (+)
XLOC_000225 tlr3 coding downstream 356637 17892944 ~ 17898227 (+)
XLOC_000213 CT573256.2 non-coding upstream 1068601 16458525 ~ 16458741 (+)
XLOC_000211 CU633160.1 non-coding upstream 1365122 16162104 ~ 16162220 (+)
XLOC_000209 NA non-coding upstream 2091017 15422226 ~ 15436325 (+)
XLOC_000227 NA non-coding downstream 429807 17966114 ~ 17970284 (+)
XLOC_000228 NA non-coding downstream 628810 18165117 ~ 18169100 (+)
XLOC_000230 NA non-coding downstream 819439 18355746 ~ 18363871 (+)
XLOC_000233 NA non-coding downstream 1292865 18829172 ~ 18833443 (+)

Expression


Co-expression Network