| Item | Value |
|---|---|
| gene id | XLOC_022401 |
| gene name | scn8aa |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007134.7 |
| NCBI id | CM002907.2 |
| chromosome length | 46223584 |
| location | 27251626 ~ 27345425 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| scn8aa | Enables voltage-gated sodium channel activity. Acts upstream of or within several processes, including mechanosensory behavior; motor neuron axon guidance; and sodium ion transmembrane transport. Predicted to be integral component of plasma membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in axon. Is expressed in heart; nervous system; otic vesicle; and trigeminal placode. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and developmental and epileptic encephalopathy 13. Orthologous to human SCN8A (sodium voltage-gated channel alpha subunit 8). |
| id | name | namespace |
|---|---|---|
| GO:0019228 | neuronal action potential | biological_process |
| GO:0034765 | regulation of ion transmembrane transport | biological_process |
| GO:0055085 | transmembrane transport | biological_process |
| GO:0007638 | mechanosensory behavior | biological_process |
| GO:0086010 | membrane depolarization during action potential | biological_process |
| GO:0006811 | ion transport | biological_process |
| GO:0008045 | motor neuron axon guidance | biological_process |
| GO:0006814 | sodium ion transport | biological_process |
| GO:0008345 | larval locomotory behavior | biological_process |
| GO:0035725 | sodium ion transmembrane transport | biological_process |
| GO:0030424 | axon | cellular_component |
| GO:0001518 | voltage-gated sodium channel complex | cellular_component |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0005887 | integral component of plasma membrane | cellular_component |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral component of membrane | cellular_component |
| GO:0005216 | ion channel activity | molecular_function |
| GO:0005244 | voltage-gated ion channel activity | molecular_function |
| GO:0005248 | voltage-gated sodium channel activity | molecular_function |
| GO:0005261 | cation channel activity | molecular_function |
| GO:0005272 | sodium channel activity | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-000828-1 | Enables voltage-gated sodium channel activity. Acts upstream of or within several processes, including mechanosensory behavior; motor neuron axon guidance; and sodium ion transmembrane transport. Predicted to be integral component of plasma membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in axon. Is expressed in heart; nervous system; otic vesicle; and trigeminal placode. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and developmental and epileptic encephalopathy 13. Orthologous to human SCN8A (sodium voltage-gated channel alpha subunit 8). |
| ensembl_id | ENSDARG00000005775 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00044198 | False | 6814 | mRNA | 0.47 | 27 | 27251626 | 27345425 |
| TCONS_00044199 | True | 6804 | mRNA | 0.47 | 27 | 27251636 | 27345425 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_022399 | si:dkey-157g16.6 | coding | downstream | 6391 | 27134942 ~ 27245235 (-) |
| XLOC_022400 | NA | coding | downstream | 52531 | 27191956 ~ 27199095 (-) |
| XLOC_022398 | stat6 | coding | downstream | 128446 | 27078866 ~ 27123180 (-) |
| XLOC_022397 | zgc:66440 | coding | downstream | 190554 | 27041111 ~ 27061072 (-) |
| XLOC_022396 | NA | coding | downstream | 236466 | 26961010 ~ 27015160 (-) |
| XLOC_022402 | dip2ba | coding | upstream | 13297 | 27358722 ~ 27442544 (-) |
| XLOC_022403 | atf7a | coding | upstream | 101504 | 27446929 ~ 27479558 (-) |
| XLOC_022404 | asb8 | coding | upstream | 149666 | 27495091 ~ 27506161 (-) |
| XLOC_022405 | larp4aa | coding | upstream | 166284 | 27511709 ~ 27547931 (-) |
| XLOC_022406 | pfkma | coding | upstream | 208361 | 27553786 ~ 27571667 (-) |
| XLOC_022393 | NA | non-coding | downstream | 492066 | 26749407 ~ 26759560 (-) |
| XLOC_022392 | CR855310.1 | non-coding | downstream | 575856 | 26675652 ~ 26675770 (-) |
| XLOC_022380 | BX005414.1 | non-coding | downstream | 1458533 | 25789132 ~ 25793093 (-) |
| XLOC_022408 | CR354381.1 | non-coding | upstream | 234739 | 27580164 ~ 27580292 (-) |
| XLOC_022412 | NA | non-coding | upstream | 307471 | 27652896 ~ 27675394 (-) |
| XLOC_022415 | NA | non-coding | upstream | 381870 | 27727295 ~ 27729454 (-) |
| XLOC_022416 | NA | non-coding | upstream | 425056 | 27770481 ~ 27772372 (-) |
| XLOC_022417 | NA | non-coding | upstream | 442944 | 27788369 ~ 27795923 (-) |
| species | gene id | symbol | gene type | chromosome | NCBI id | location |
|---|---|---|---|---|---|---|
| bowfin (Amia calva) | AMCG00008906 | LOC108433193,LOC104932970 | coding | CM030126.1 | CM030126.1 | 14419818 ~ 14455800 (+) |