XLOC_002287 (smyd4)


Basic Information

Item Value
gene id XLOC_002287
gene name smyd4
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 36092564 ~ 36106146 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004367
TATTTTGGAAATTGATAAAAGCTCCAACCGGAAGTCAAGTTGTTGTTGTGAAATTTAAAGTGTTGGAGGGCTTCGTACTTTTCGCTTGTGTGTTAACAGTTATTTGAGTGGGTTTTGAATGGATCTGCCCTGCCAAGATTGGGTTTGTCATGTCGAGCAGAAATGGGCTGAACTGAGATCTGAAGAAACTGAGCGTTTCAGCCTTCTGACTGATATAGATGCCATATTCAACTACGGGCTGTCACTAATATGTCCAGAGGATCTCAACATTCTGTCCAGAATCTCAGAGAAGTTTTCCGTCAAAAAGTCTCCTGAAACAGCTTCTGAGTTTAGACAGCAAGGCAACCTCAGCTTCAAAGTCAAGGATTACCCCGCAGCAGTGCTTCATTACTCCAAGGGTGTTTGCCATGCTGACAAGAATACAGATGAGCTCTCCTTGTGCTATGCTAACCGTTCTGCTGCCCTATTTTACCAAGGCCTCTACCAAgcaTGTCTTGAAGACATCAGGCGTTCTCTGGAGGCCGGTTACCCAAGCCACCTGCAGGACAAACTACAAACTAGACAAACCGCCTGCCAGAATCAGCTAAGAAAAGCTGAAAAACCCAACATACCACACACAGATCATCAATTATCACCATGCCAGAAGACTGTAAACTCTACTGGTCATCTTTCAGATGGTGTATCTGTTTATTTCAGCTCGGACAAAGGTCGCCACATGTTAGTCATGGAGAATAAACCAGCTGGAGAAGTGGTGCTGGAAGATGAAGCTTACTGTTCTGTCCTTATACCAGCTAACATATTTAATACAGGAACCAATAAGGCGGTAGAGACATTTGGTACTGAAGATCGACATTGTCACCACTGCCTCAGCCAGTCACTGAGTTTTGTGCCCTGTCCAAAGTGTAGTTACGCTCGATATTGTGGAGAGAGCTGTCAGAAAGATGCATGGGATCAATGGCACCAGTGGGAATGTCCAGTTGGAGCTGATCTGCTGGCCATTGGGGTTTTGGGACATTTAGCACTAAGAGTGGTCCTTAAAGCAGGACAAACTGAAGTCCAAATGGGGATTAAAAACACAAAAGACCATGTGACCACTTATAAAAATGATTCACCAGTCCAGTTGAGTCTCGGAGGGGACTGTGGAAAAAGTTTAGACCATACAGACTGTTTTCATGGCAGCTCATACATGGGCATCTATAGCCTTTTACCGCATGTGGCACAACACTCACCTGCTTCACGCTTCTTAATGGCCATCACCATGGCGGTGATTTACGGGAAGCTTCAAGGCGGACCTCCACCAAACAAGTGGATGTCCTTCAAAGACGAAGGAGTTAAAGCAAGCTGGCAGCCTGAGATGAGCATGCTGGGAGCCACAGCTCTGAGGCACATGATGCAGCTAAGGTGTAATGCTCAAGCAATCACTGCTGTTAGGGTCAAAGAAGAAAGTGGCATGGCTGTTCAGTCCAGCAGTGAAATCCGTATTGCCACAGCTATATTCCCTGTGCTCAGCCTGCTTAACCACTCCTGCAGTCCAAACACAAGCATCTCCTTCACTACAGGATTTCAGCCTGACCCACATAATCAGTTGGGCTGTTCTGAAGGTCACTTTGACCATCCCAAGGGCTCTCGGTCTGGTGTGACGGTCACTGTACGTGCTTCAAAAGACCTCACTGCAGGACAGGAGATTCTGCACTGTTATGGCCCTCACCGTAGCAGAATGGAGGTGAAGGAGCGTCAGCGCCTCCTGCTGGAGCAGTACTTTTTCCAGTGTGTATGTCAGGCCTGTCAGAGAGATCTGTCAGAAGGAAGCCCGAATGCAAAAGAACACACAGCACCAGGGATGAAGTGTGTGAAATGTGGAAAGCCTCTTCAGTCCCATACGGATGGATACACATGCTCTTGGTCATCCTGTGGTCATCAGATCAGCAGTGCTGATGTCCAAAACAGACTTCAGGGTTTTCAGCTTCTTTTGGATGAAGCTGTTCATCTCATGGAGCAAGACAGATTGAATGAGGCCTTACACATCCTCCAATCAGCTTTTTCTCAGGCAAACAGTATCCTGACTGAGACTCATCCTTTCCAAGGAGAGCTAGCAGATGCTCTGGCTCGGCTGTACGCCAGCACAGGTGAATGGAGTCTGGCTGCATCTCATCTGAAGCGCAGTCTTGTTGCCATTCAGGCTCAGTTTGGAGAGGACAGCATTGAGCTGGGTCGACAGCTTTTTAAATTAGCTCAGCTACATTTTAACGGAAGGGATGGTGTTGCGTCTCTCTCTGTGATTCCCAGAGCCCGAAGGCTGCTCTCTCTCCACTGCAGCCCTCGCTGTGAAGAACTGCAGGAACTGAGTGAAATGGAGCACTGTCTTCAAGGGCTGCTATGAAACAATGACTGAAAACTGACAAGCTTCTTTTTCTGATATACTGTGTGTAAAGTaggattaaaaaacataaattaactgtGTGATGTGctattttattaaagttcttGGTGCCCAAgctatatctctctctctctctctctctctctctctctctctctctctctctctctctctatatatatatatatatatatatatatatatatatatacatacacattttttaaaatagtttaaattatttaattaggacagtaaggtctgactttgctttgacaagtcttgtcacttaacagaaataatgtacatctGAATGGCAATGGAATTTggaaagaaagcgttcctgcaggactactagagttcatcaagattctttggattcatcttcaaagtcttctccatcttacctcagacatgctcaataatgttcatgtctggtgactgggctggccaatcctggagcaccttgaccttctttgctttcaggaactttgatgtggaggctgaagtatgagaaggagcgctatcctgctgaagaatttgccctcttctgtggtttttaatctaatgggcagcacaaatgtcttgatacctcaggctgtggaTGTTGCTATTCACTCtgtagatctctcgcacgcccccatattgaatgtaacccacaaaccatgatttttttcttcaccaaacttgactgttttCTATGAAAATCTTGGggccatgcaggttccaataggtcttctgcagtattgggatgcagttcaacagatgatttatgataaaaatctaccttctgccacttttgctaatgatcaactagaagtcaagttatttgttgcttctaaaactgggatcgacgacaagactttgtgttttatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatatgaaaaagaaagaagattattatgcaagaaaaaaatatgtaaaatgttcaattaaaatgACCGATGACATATTTGTAATTACAATATGTTTTATGATTTTATCTATTAAAAAGTGTATTAAACAACATCAACACATGTAAATGGGAGattcaattcaataaaaaaaagtccCTGTCCTTTCTCAATAATTTCagtattacaatatatataaatatacaagaaTTTCACGTAAAAAGCTAATATTTGGGGTCATTTTAGCTTGAAAACAGTTTGCTGGGCCACTAGATGGCGGTCTTTGACAAACATGAATGAAATGCGTGTGAGACGTGAAGCGAATTACCAACATTAATGTCACTCACTGGAATAAATAagattacatttgttttaatgtgtAACTCTTGACTGCTCAGAAACAGTACAATTGAATGAATCCCACACACATTTATGTATAATGCCATGAAAATTTCATAAGCTTTCACTTAATAGACTTCTCTGTCAGCAATGATTTGTCAAGAAAAGATACACATTTATTCATCCTTAGACCATCTAAGTTGGTAACTTTTGGTCAAACGATTTTTGTAGCTGCGATCCTTTCTTATTAATGCAAGCCTGCTAGGTACCaaccagggtgcgaattacagggagGGGGGTCTGACCCCCAATTAACGCTTGATCTCCCCTGAAGCACATCTAAAAATGGTGTACAGG

Function

symbol description
smyd4 Predicted to enable metal ion binding activity. Acts upstream of or within heart looping and negative regulation of histone deacetylase activity. Is expressed in blood vessel; cardiac ventricle; heart; heart tube; and polster. Used to study congenital heart disease. Orthologous to human SMYD4 (SET and MYND domain containing 4).

GO:

id name namespace
GO:0003007 heart morphogenesis biological_process
GO:1901726 negative regulation of histone deacetylase activity biological_process
GO:0001947 heart looping biological_process
GO:0061371 determination of heart left/right asymmetry biological_process
GO:0046872 metal ion binding molecular_function

KEGG:

id description
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-060929-248 Predicted to enable metal ion binding activity. Acts upstream of or within heart looping and negative regulation of histone deacetylase activity. Is expressed in blood vessel; cardiac ventricle; heart; heart tube; and polster. Used to study congenital heart disease. Orthologous to human SMYD4 (SET and MYND domain containing 4).

Ensembl:

ensembl_id ENSDARG00000060983

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004367 True 4032 mRNA 0.42 10 36092564 36106146

Neighbor

gene id symbol gene type direction distance location
XLOC_002286 katnal1 coding upstream 29150 36037977 ~ 36063414 (+)
XLOC_002285 hmgb1a coding upstream 60526 36026576 ~ 36032038 (+)
XLOC_002284 rtn4rl1a coding upstream 132993 35952532 ~ 35959571 (+)
XLOC_002283 dre-mir-132-2 coding upstream 447429 35645017 ~ 35645135 (+)
XLOC_002282 BX663516.1 coding upstream 447766 35644719 ~ 35644798 (+)
XLOC_002288 waif2 coding downstream 44765 36150911 ~ 36156658 (+)
XLOC_002289 BX088524.3 coding downstream 52821 36158967 ~ 36160287 (+)
XLOC_002290 or108-3 coding downstream 72567 36178713 ~ 36180091 (+)
XLOC_002291 or108-2 coding downstream 78605 36184751 ~ 36186346 (+)
XLOC_002292 or108-1 coding downstream 88381 36194527 ~ 36196218 (+)
XLOC_002277 NA non-coding upstream 678287 35369592 ~ 35414277 (+)
XLOC_002271 NA non-coding upstream 850536 35236348 ~ 35242028 (+)
XLOC_002269 NA non-coding upstream 1034003 35054311 ~ 35058561 (+)
XLOC_002294 NA non-coding downstream 95038 36201184 ~ 36381043 (+)
XLOC_002299 BX088524.1 non-coding downstream 181695 36287841 ~ 36288503 (+)
XLOC_002315 CU694807.1 non-coding downstream 620092 36726238 ~ 36733011 (+)
XLOC_002317 NA non-coding downstream 698890 36805036 ~ 37064390 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000304_17266905_17272656 SMYD4 coding CI01000304 null 17266244 ~ 17272740 (+)