XLOC_000255 (prss12)


Basic Information

Item Value
gene id XLOC_000255
gene name prss12
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 20069535 ~ 20141844 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000421
ATGGATGTGAGGTGTCGGTTCGTCTTTACGGTCTGCGCGCTTCTGCTTATGATCGCGCGCACTGGCGGCTCTCCGTTCACTGACTGTGTTCAGAGCAAAGGGAAAGCGGGCTTTTACGAGGGGTCCATTGACTCAACCGAATCAGGCGTGAAGTGCATGAACTGGAGCGATGTGCCCGGTGTTAGAGAGCGGTATCAAGGTAAAGGGCTCGGAGATCACACTTTCTGCCGAAATCCGGACGGGAGAATTCGGCCCTGGTGCTTCTTCACGAACAACAGAGGACGCATTGACTGGGGATACTGCGACTGCAAGCAGGGCTCTTTGCGACTGCAGGGAGGCAGATCTAAACTGGATGGTACAGTAGAAGTGTATCTCAATGGTGTGTGGGGAACCATCTGCAGTAATGGCTGGGATGACCAAGATGCCGCTGTGGTGTGTCGACAGCTGGGACAGGGCTATAGAGCACATGCACGCATGAGTCCTCTGTCACGTCTGGTGGTGTCTGTAGTTCACTGGCAGACTGTGGGCTGTGAAGGACAGGAAGATGACTTACTGCAATGCAATCGCACCGTCTGGAACGGGGGAGAGTGTGAGAATCGCCAAGCGGCTGCTGTTTCTTGCATGCCGGTGGAGACTTCAGTGTTTGTCCCAGTGCGGCTATCTGGTGGTCCATCGGCATATGAGGGCAGAGTAGAGGTGTATCATGCAGGACAGTGGGGCACAGTTTGTGATGACCAATGGGATGATAACGACGCTGAGGTGGTCTGCAGGCAGCTGGGGTTAGGTGGCATTGCGAAGGCTTGGGTGGGAGCGTATTTCGGCGCAGGCTCTGGGCGTGTGTTTTTGGATGAGGTGAGCTGCACCGGAAATGAGCTTTCAATAGAGCAGTGTCCAAAAACTGCCTGGGGGGAGCATAACTGTGACCACACAGAGGATGCTGGAGTGTCCTGTGTACCACTTACAGACGGTGCAGTGCGTCTGGTTGGGGGTGTAAAGGGTTATGAAGGGAGACTGGAGGTCCATTACAGAGGACAGTGGGGGACTGTGTGTGATGATGGCTGGACACAGACTAACACACAGGTCGTCTGCAGGCAGCTGGGTTTCAGGTCAGGGGAGAGTGTATCAGCAGGGCGGTTTGGGATAGCGGCAGGTCCTGTTCTTCTGGATGATGTGCGCTGTACTGGAAAAGAGCCCACGGTCACACACTGCAGCCGGAGGGGTTGGTTTAAACATGACTGCACTCACAGACAGGATGTAGCCATTGTGTGCAGCCCCCAATGCTCCAGACATGGAGTACCCAACAGTTTACCTGTGAGGCTGGTGGGcggagagaatgagagagaggggCGTGTAGAGATCCTGGTGGGTGGCCAGTGGGGGACGGTGTGcgatgatggatggacggatcGGGACGCAGAAGTGGTGTGCAGACAGCTGGGTTACAGTGGGCTGGCTAAAGCTCGTGTAATGGCATATTTCGGAGAAGGCGAAGGTCCTATCCACATTGACAATGTAAAGTGTACAGGCGGGGAGCATTCCCTGACTGACTGTATCAAACAGCCATTCGGGACACACAACTGTCGCCATAGTGAGGATGCCGGTGTTATTTGTAACTATGGGTTACAGCAGGATTCTCCTGGGGTCAAAGTTGGCTCCATGTGTGGTCTAAGACTCTCTCACACACGTCAGAAGAGAATTATAGGAGGAGAAAACTCTCTACgTGGTGGCTGGCCGTGGCAGGCAGCTGTGCGTTTACGGGGTTCTCAGGCAGATGGACGCTTGGTATGTGGAGCTACTTTGATCAGCAGCTGCTGGATCCTCACTTCAGCTCACTGCTTTAAGAGGTATGGGAACAGCACAGGGCTGTATAAAGTTCGTGTTGGTGATTATCACTCTCTGGTCCCTGAGGAGTATGAGGAAGAGTATGCCGTGGAGAAGATCGTCCTTCACCCACGCTACCATGCAGACAGTAGTGACTATGACCTGGCACTTCTGCGTGTTTCTGGACACAGAGCTCACAGGGGTGTCACGGGCCAATGCGTCACACTGAGCCGATCAGTGCTGCCCGCTTGTTTACCAGTGCGGAGAGAGAAAGTGCCAAAGGGCATTGCCAACTGCTACATCACAGGCTGGGGAGATACAGGTCGTGCATATTCCAAAACTCTCCAGCAGGCCTCCATTTCTGTGTTGAGCAAGCGTCAGTGTGAGCAGCGCTACTCGGAGCAGTTCACCAATCGTATGCTGTGCGCCGGCTCGTCCCATGATGCCCAGCGTGTGGACTCCTGCCGTGGCGATAGCGGTGGTCCGCTGGTGTGCGAGAGGCCAAGCGGGAGCTGGGTTGTTTATGGGGTCACATCATGGGGTCACGCGTGTCGCCTGCAGGAAGCACCCGGGGTATACACCAAAGTCTCCGCCTTTGTGCCCTGGATTAAGAAAGTTATTGGCCAGTAG
>TCONS_00000422
GCTATAGAGCACATGCACGCATGAGTCCTCTGTCACGTCTGGTGGTGTCTGTAGTTCACTGGCAGACTGTGGGCTGTGAAGGACAGGAAGATGACTTACTGCAATGCAATCGCACCGTCTGGAACGGGGGAGAGTGTGAGAATCGCCAAGCGGCTGCTGTTTCTTGCATGCCGGTGGAGACTTCAGTGTTTGTCCCAGTGCGGCTATCTGGTGGTCCATCGGCATATGAGGGCAGAGTAGAGGTGTATCATGCAGGACAGTGGGGCACAGTTTGTGATGACCAATGGGATGATAACGACGCTGAGGTGGTCTGCAGGCAGCTGGGGTTAGGTGGCATTGCGAAGGCTTGGGTGGGAGCGTATTTCGGCGCAGGCTCTGGGCGTGTGTTTTTGGATGAGGTGAGCTGCACCGGAAATGAGCTTTCAATAGAGCAGTGTCCAAAAACTGCCTGGGGGGAGCATAACTGTGACCACACAGAGGATGCTGGAGTGTCCTGTGTACCACTTACAGACGGTGCAGTGCGTCTGGTTGGGGGTGTAAAGGGTTATGAAGGGAGACTGGAGGTCCATTACAGAGGACAGTGGGGGACTGTGTGTGATGATGGCTGGACACAGACTAACACACAGGTCGTCTGCAGGCAGCTGGGTTTCAGGTCAGGGGAGAGTGTATCAGCAGGGCGGTTTGGGATAGCGGCAGGTCCTGTTCTTCTGGATGATGTGCGCTGTACTGGAAAAGAGCCCACGGTCACACACTGCAGCCGGAGGGGTTGGTTTAAACATGACTGCACTCACAGACAGGATGTAGCCATTGTGTGCAGCCCCCAATGCTCCAGACATGGAGTACCCAACAGTTTACCTGTGAGGCTGGTGGGcggagagaatgagagagaggggCGTGTAGAGATCCTGGTGGGTGGCCAGTGGGGGACGGTGTGcgatgatggatggacggatcGGGACGCAGAAGTGGTGTGCAGACAGCTGGGTTACAGTGGGCTGGCTAAAGCTCGTGTAATGGCATATTTCGGAGAAGGCGAAGGTCCTATCCACATTGACAATGTAAAGTGTACAGGCGGGGAGCATTCCCTGACTGACTGTATCAAACAGCCATTCGGGACACACAACTGTCGCCATAGTGAGGATGCCGGTGTTATTTGTAACTATGGGTTACAGCAGGATTCTCCTGGGGTCAAAGAGGCAGTTGGCTCCATGTGTGGTCTAAGACTCTCTCACACACGTCAGAAGAGAATTATAGGAGGAGAAAACTCTCTACgTGGTGGCTGGCCGTGGCAGGCAGCTGTGCGTTTACGGGGTTCTCAGGCAGATGGACGCTTGGTATGTGGAGCTACTTTGATCAGCAGCTGCTGGATCCTCACTTCAGCTCACTGCTTTAAGAGGTATGGGAACAGCACAGGGCTGTATAAAGTTCGTGTTGGTGATTATCACTCTCTGGTCCCTGAGGAGTATGAGGAAGAGTATGCCGTGGAGAAGATCGTCCTTCACCCACGCTACCATGCAGACAGTAGTGACTATGACCTGGCACTTCTGCGTGTTTCTGGACACAGAGCTCACAGGGGTGTCACGGGCCAATGCGTCACACTGAGCCGATCAGTGCTGCCCGCTTGTTTACCAGTGCGGAGAGAGAAAGTGCCAAAGGGCATTGCCAACTGCTACATCACAGGCTGGGGAGATACAGGTCGTGCATATTCCAAAACTCTCCAGCAGGCCTCCATTTCTGTGTTGAGCAAGCGTCAGTGTGAGCAGCGCTACTCGGAGCAGTTCACCAATCGTATGCTGTGCGCCGGCTCGTCCCATGATGCCCAGCGTGTGGACTCCTGCCGTGGCGATAGCGGTGGTCCGCTGGTGTGCGAGAGGCCAAGCGGGAGCTGGGTTGTTTATGGGGTCACATCATGGGGTCACGCGTGTCGCCTGCAGGAAGCACCCGGGGTATACACCAAAGTCTCCGCCTTTGTGCCCTGGATTAAGAAAGTTATTGGCCAGTAGAAAATTATGGTGAACAAAATAGTATTCTGACTTTGTGGGCATAAACAATGAAGCACATTTTAGATAATATTTTGAAAACTATTTCTTAACACTAGCTGAAATTAccttttaaacaagtcttaaatgcCAGAGAGAAAGGCTACGCTTTGCTTTAAAGGGGCTATATGTACGCATTTTCATGTATTTTATTGCCATTGTGAGGTTTATGAAAGGTTGTAGACTGATACTGTAGTTGTGAAGGACACAAAAGGATATGGTGTTTACAAACGCTCCTGAGAGCCTCTCTTTTCTTCTTTGGCACATGAACGAGTGCTATAAAAATGCTTAAGATCATGCTGAAAGAGCCGTACTGTAATGTCAATGTGTCAAACGAAGAAAGGAGATTCATTTAAATCACATCTTGTGGATGTTTAGTCTGTAGTAGGGATGTACGatgttgattaattaatttaattaacgtTAAAAGTAAACCTTTGTGACTAGTCTAACAAACCCACAGACTGTTGAAAAACAGTATTTATGGTATATAGACTCACTGAACACTTTATTAAGTAGCTACACCTTACtataccaggttggacccacttttgccttcagaactgccttaatcctttgtggcaaagATTTCACAAGGgactggaaaattcctcagagattttggtctttattgagatgatagcatcacatagtgagttctatgatgcgaatctcctgttccaccacatcccaaagttgctctattggattgagacctggtgactgtggaggccatttaaatacagtgaactcattgtcatgttcaagaaaccaatctgagatgatttgtgctttatgacatgatgcattatcctgctggaagtaactaTAAGAAGATAGGTacagtggtcataaagggatggaccaggcaacatttttccaatcttctattgtccaacttCGGTGAGTctgtgagaattgtagcctcagtttcctgttcttaactgacaagagtggcacctggtgtggtcttctgctggtTCTGGTTCTGTCAACAAGGCGTTTGTTGCTGGGTTCTCGAGATATACCGGAGCTCAAACTTCCCtttcgccctgcaaacgggagggagccccgggcttgaggatctcattggctcagggctctctcccgggacagcatgccaaactagcttattaccaatcatcagccaagtgtgaactcttgcaattggccttagtgtatgtgtgtgtgaatgagagtgtaagggtgtttcccagtactgggttgcagctggaagggcatctgctgtgtaaaacgtatgcttgataagttggtggtacattccactgtggtgacccctgataaataaagggactaagccgaaggaaaaagaatgaaatgaatgaatattgccgCTCGCTTGAAACGGATATTGCATATACTTTTTTTagatattgtgcagctctactaggCAGTCTAGTACCAAAAATTACAAGCTTTAATAGAATTTGTGAACTAAAAGTAAATTGAAATACTGTAGTATATTGTATTTGGGGTGCTTTGTTACATTCAGTCTCCTGTTTCTCGTGTGCAGTATGAGCTAGCAGTGGTTTCTGAAATCTACATATAGCCCTTTTAAGTGTGGGGTGATGAAGGGATGAAGTCAAAAACCAGAAAAATGATTTACAGTCAGTGGGTAAAATGTGTTCTGTGATAATTGTATTTCAACATATTTCCCATAACCAGGCTTCCATAATATATATTTGCTATAATTTCAACTAGTGGGCACTGAACTGAAAATGTAGGTTGCAGAAAGCTTCCTTGCACAACCTACAAGTTTTTGGCTGTTTTTGTACaaggacatttaaaatattttttttaaagaatgattaGCTTTAGTAGAGTTGGATTTTAAATTGGGAATAAATCTAAACACACTGAATAAAGTCAGTATTTGTGGGTTTAAAAATTCATGACAAAATGCATAGAGTTGTCTTAAACTTTCCTTTTTTTATGAAAGCACTTCAAGGGTTGAAGAGACCACATTGGTGATTGTGGAATTAttctgatttctttttttaatgaacatgTATCCAAGTGACTGTATTCTTCTTACCATTAAGAAATAAGCACAAACTTTAAACCATAAACCAGGATGTGTAATGTTTCTCAGTTGATACCTATTTGAGCGTCTTGAAGAACGTTCCGATGGCTTGAAATCACATCAGGCTTTAATGCTGAAATGAGAAGATTCTGGATTTCCTGCCAAGAAATCTATGGTAATTCTAAACTCTTGGGAAACGGTTACCATGCCATTGCTTAGAAACGGACCGCATCACCTCATCAACACATTAGATGACATCATAATCCATCCATGACTTCATTTGTTATAGATCAGATGACGGTGACGATAACTGGACTGAGGCTTGCTGTCTTAACATGAGGCCAttttacatgcatacatacactcaccggccactatattaAGTACACCGTACAAGTACTgagttggatccccttttgcctaCAGGACTTCcataatcctttgtggcatagttttaataaggtactggaaatattctttggagattttttgtccacattgacatgatagcatcacaaagTTGCTGAAtctccatgatgcgaatctcccgtccagtacatcctaaaggtgctctattggattgagatctggtgactgtggaggctgtttgagaacagtgaactcattgtcatgttcaagaaaccagttgccgccaaattctgaccctacctcCGGAATGTCGCAGGAGAAATCAAGACTCAGCAGATCAGGCAACCATCACCtcaaaatcacctttcttccccattctgatgctcagtttcaactgcagcagatcatcttgaccctgtctacatgcctaaatgcattgagttgctgccatatgattggctgtttagaaatttgcgttaacaagcagttggacaggtgtacctaaaaaagtggctagtgagtgtaCATCCGCCTAATATTTTTGCAGTCACACTCTCTTCCAGAAGGAAATGGGAATTATGTGCAATGGCAGACTCTTTAAACAACTTTGTTTTATGACTGTGTTAATTAGAGCGCTTTATGTTAGCATAATAAATGGTCTTCAATTTATGTTTTCTGTGATCTGTGTCTATAATAAACCATCATAAGCATGATTTATGAGCGTAGAGACTAGTACGGCCTTTTTATT

Function

symbol description
prss12 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human PRSS12 (serine protease 12).

GO:

id name namespace
GO:0031638 zymogen activation biological_process
GO:0006508 proteolysis biological_process
GO:0030425 dendrite cellular_component
GO:0043083 synaptic cleft cellular_component
GO:0005886 plasma membrane cellular_component
GO:0043195 terminal bouton cellular_component
GO:0016020 membrane cellular_component
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function
GO:0005044 scavenger receptor activity molecular_function

KEGG:

id description
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-090313-45 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human PRSS12 (serine protease 12).

Ensembl:

ensembl_id ENSDARG00000061830

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000421 False 2451 mRNA 0.55 13 20069535 20138647
TCONS_00000422 True 5200 mRNA 0.45 11 20084389 20141844

Neighbor

gene id symbol gene type direction distance location
XLOC_000254 NA coding upstream 40469 20026889 ~ 20029066 (+)
XLOC_000253 NA coding upstream 41609 20023932 ~ 20027926 (+)
XLOC_000252 apbb2b coding upstream 79951 19930520 ~ 19989584 (+)
XLOC_000251 UBA6 coding upstream 183146 19849168 ~ 19886389 (+)
XLOC_000250 NA coding upstream 248340 19808441 ~ 19821195 (+)
XLOC_000256 NA coding downstream 4561 20146405 ~ 20147549 (+)
XLOC_000257 si:ch211-142c4.1 coding downstream 451809 20593653 ~ 20607152 (+)
XLOC_000258 spock3 coding downstream 493346 20635190 ~ 20706296 (+)
XLOC_000259 CT583646.2 coding downstream 794867 20936711 ~ 20938512 (+)
XLOC_000260 CR762427.1 coding downstream 1112509 21254353 ~ 21254482 (+)
XLOC_000247 BX323590.2 non-coding upstream 363703 19705699 ~ 19705832 (+)
XLOC_000239 NA non-coding upstream 804565 19253027 ~ 19264970 (+)
XLOC_000262 NA non-coding downstream 1189581 21331425 ~ 21341653 (+)
XLOC_000263 NA non-coding downstream 1358801 21500645 ~ 21501484 (+)
XLOC_000269 NA non-coding downstream 2368890 22510734 ~ 22518754 (+)

Expression


Co-expression Network