XLOC_030463 (traf2b)


Basic Information

Item Value
gene id XLOC_030463
gene name traf2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007116.7
NCBI id CM002889.2
chromosome length 72500376
location 54422941 ~ 54453848 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00059520
ATGTGGCTTGGATACAATCTTCCATCATACTTCTCTTCGATGATCAGCGCTGCAGGCACTCTGTGTAAATGGAAGGATATGGAACGTCCATCTTTACCATCTTCTCTGGACTCAACATTGCCTGGGATATCTCGAGAAGTGCTGTCGGTGTCCATGGAACCGAAATATCAATGCCAGCAGTGCAAAGATATTCTTAGGAAACCTTTCCAAGCACAATGTGGACATCGCTTCTGTGTGTTCTGTTTCAAACAACTGACCAGctCAGGGCCCATACCCTGCGAAGCCTGTCGTGCTGAGGGTATATTTGAAGAGGAAACGTCTGTGCTTAATATTGCAGTGGCATTTCCTGATAATGCAGCACGAAGAGAAATTGATAGCTTGCCTGCTAAATGCCCAAATGAAGGTTGTAGTTGGTCTGGGACACTGAAGGACTTTGAGAATCAACATGAAGGTCGCTGTGCCTTTGAACGTGTGAAATGTGAAGCATGTCAAGTGCTTATATTGCTCTCTGAGAAGGACCGTCACAATGAGCGGGAATGTGAAGCCAGAACCCTCAACTGTAAATACTGCAAAGTCACATTCAACTTTAAGGAAATTAAGGCCCATGATGAAATTTGTCAGAAATTTCCCATGCAATGCAAAGACTGTGGTAAAAAGAAAATACCCAGAGAGAAGTTTCAAGAGCACACCAAATCTTGTGCAAAATCTAAGTCAGCATGCCAGTTCAGAGAGATTGGTTGCAGGGCAGTGGTTGACAATTGCAAGCAACAGGAGCATGAGCAGACCAGCATAATGGAGCATTTGCGTCTGATGTTAGCTTTGCTATCCTCCATGCGCCTGCGAGCAGAAGGGGCTGGAGAGTGGCAGGAAGACGTTGGGCTGGGATTGTATCGCGGACCTGAAGATGCACCACCAGCAGGAGCTCATAATGTAGGAAGAGGAGGCGGTCCTGGTGTTCAGAAAAAAGTCACAACTTTGGAGAACATAGTGTGTGTCTTGAATAAAGAGGTGGAACGCTCTGCCCTCACCATGGAGGCGATATCCCGGCAACATCGCCTGGACCAGGAAAAAATTGAGAATTTGTCAAACAAGGTGCGACAGTTGGAACGGACGTTAACCACGCGAGATCTGCAGTTAGCAGAATCTGAGCAGTCTTTGCGGGAGCTGCAGTTTTGTACATATGATGGGGTTTTCATTTGGAAAATTGCAGAATTCTCTCGACGCAGGCAAGACGCAGTGGCAGGCCGAGCACCTGCCATGTTCTCACCTGCATTTTACTCCAGTAAATATGGGTATAAGATGTGTCTGAGACTGTACCTGAACGGTGATGGCACAGGTCGAGGCTCTCATCTCTCTCTGTTCTTTGTGGTCATGAAAGGCAAATATGATGCTCTGCTGAAGTGGCCCTTCAGCCAGAAGGTGACATTGATGCTGTTGGACCAAAATAACAGAGAGCACATCATTGATGCCTTCAGGCCTGACGTGAGCTCCACATCTTTCCAGAGACCCATCAGTGAGATGAATATAGCCAGTGGCTGTCCTCTCTTCTGCCCCCTCGCCAAGCTGGCAGGCAAAAGCTCATATCTGAGAGACGACACCATATTTATTAAAGCCATAGTCGACCTTACTGGCTTATAA
>TCONS_00059521
TGACACGCCTCATGACATAAcgacgttttttttttacagtacttggAACTATTTGGTGAGTAACTTCTTCGTGTTTGTTCGTGTTTTCGACGTTCCTATTCCATCGAGTTCGTTACAATTTACTAGTATTTGAAAAGTCTGCGTAGTGTGGTGGTGCTGCTGCGAGTTGCCATTTTTACACACTCTCTCTTGGAGAACCAGGAAACAACCAATGTACGCTTCTTTTAACTATGATCAGCGCTGCAGGCACTCTGTGTAAATGGAAGGATATGGAACGTCCATCTTTACCATCTTCTCTGGACTCAACATTGCCTGGGATATCTCGAGAAGTGCTGTCGGTGTCCATGGAACCGAAATATCAATGCCAGCAGTGCAAAGATATTCTTAGGAAACCTTTCCAAGCACAATGTGGACATCGCTTCTGTGTGTTCTGTTTCAAACAACTGACCAGctCAGGGCCCATACCCTGCGAAGCCTGTCGTGCTGAGGGTATATTTGAAGAGGAAACGTCTGTGCTTAATATTGCAGTGGCATTTCCTGATAATGCAGCACGAAGAGAAATTGATAGCTTGCCTGCTAAATGCCCAAATGAAGGTTGTAGTTGGTCTGGGACACTGAAGGACTTTGAGAATCAACATGAAGGTCGCTGTGCCTTTGAACGTGTGAAATGTGAAGCATGTCAAGTGCTTATATTGCTCTCTGAGAAGGACCGTCACAATGAGCGGGAATGTGAAGCCAGAACCCTCAACTGTAAATACTGCAAAGTCACATTCAACTTTAAGGAAATTAAGGCCCATGATGAAATTTGTCAGAAATTTCCCATGCAATGCAAAGACTGTGGTAAAAAGAAAATACCCAGAGAGAAGTTTCAAGAGCACACCAAATCTTGTGCAAAATCTAAGTCAGCATGCCAGTTCAGAGAGATTGGTTGCAGGGCAGTGGTTGACAATTGCAAGCAACAGGAGCATGAGCAGACCAGCATAATGGAGCATTTGCGTCTGATGTTAGCTTTGCTATCCTCCATGCGCCTGCGAGCAGAAGGGGCTGGAGAGTGGCAGGAAGACGTTGGGCTGGGATTGTATCGCGGACCTGAAGATGCACCACCAGCAGGAGCTCATAATGTAGGAAGAGGAGGCGGTCCTGGTGTTCAGAAAAAAGTCACAACTTTGGAGAACATAGTGTGTGTCTTGAATAAAGAGGTGGAACGCTCTGCCCTCACCATGGAGGCGATATCCCGGCAACATCGCCTGGACCAGGAAAAAATTGAGAATTTGTCAAACAAGGTGCGACAGTTGGAACGGACGTTAACCACGCGAGATCTGCAGTTAGCAGAATCTGAGCAGTCTTTGCGGGAGCTGCAGTTTTGTACATATGATGGGGTTTTCATTTGGAAAATTGCAGAATTCTCTCGACGCAGGCAAGACGCAGTGGCAGGCCGAGCACCTGCCATGTTCTCACCTGCATTTTACTCCAGTAAATATGGGTATAAGATGTGTCTGAGACTGTACCTGAACGGTGATGGCACAGGTCGAGGCTCTCATCTCTCTCTGTTCTTTGTGGTCATGAAAGGCAAATATGATGCTCTGCTGAAGTGGCCCTTCAGCCAGAAGGTGACATTGATGCTGTTGGACCAAAATAACAGAGAGCACATCATTGATGCCTTCAGGCCTGACGTGAGCTCCACATCTTTCCAGAGACCCATCAGTGAGATGAATATAGCCAGTGGCTGTCCTCTCTTCTGCCCCCTCGCCAAGCTGGCAGGCAAAAGCTCATATCTGAGAGACGACACCATATTTATTAAAGCCATAGTCGACCTTACTGGCTTATAA
>TCONS_00059522
gacgttttttttttacagtacttggAACTATTTGATGATCAGCGCTGCAGGCACTCTGTGTAAATGGAAGGATATGGAACGTCCATCTTTACCATCTTCTCTGGACTCAACATTGCCTGGGATATCTCGAGAAGTGCTGTCGGTGTCCATGGAACCGAAATATCAATGCCAGCAGTGCAAAGATATTCTTAGGAAACCTTTCCAAGCACAATGTGGACATCGCTTCTGTGTGTTCTGTTTCAAACAACTGACCAGctCAGGGCCCATACCCTGCGAAGCCTGTCGTGCTGAGGGTATATTTGAAGAGGAAACGTCTGTGCTTAATATTGCAGTGGCATTTCCTGATAATGCAGCACGAAGAGAAATTGATAGCTTGCCTGCTAAATGCCCAAATGAAGGTTGTAGTTGGTCTGGGACACTGAAGGACTTTGAGAATCAACATGAAGGTCGCTGTGCCTTTGAACGTGTGAAATGTGAAGCATGTCAAGTGCTTATATTGCTCTCTGAGAAGGACCGTCACAATGAGCGGGAATGTGAAGCCAGAACCCTCAACTGTAAATACTGCAAAGTCACATTCAACTTTAAGGAAATTAAGGCCCATGATGAAATTTGTCAGAAATTTCCCATGCAATGCAAAGACTGTGGTAAAAAGAAAATACCCAGAGAGAAGTTTCAAGAGCACACCAAATCTTGTGCAAAATCTAAGTCAGCATGCCAGTTCAGAGAGATTGGTTGCAGGGCAGTGGTTGACAATTGCAAGCAACAGGAGCATGAGCAGACCAGCATAATGGAGCATTTGCGTCTGATGTTAGCTTTGCTATCCTCCATGCGCCTGCGAGCAGAAGGGGCTGGAGAGTGGCAGGAAGACGTTGGGCTGGGATTGTATCGCGGACCTGAAGATGCACCACCAGCAGGAGCTCATAATGTAGGAAGAGGAGGCGGTCCTGGTGTTCAGAAAAAAGTCACAACTTTGGAGAACATAGTGTGTGTCTTGAATAAAGAGGTGGAACGCTCTGCCCTCACCATGGAGGCGATATCCCGGCAACATCGCCTGGACCAGGAAAAAATTGAGAATTTGTCAAACAAGGTGCGACAGTTGGAACGGACGTTAACCACGCGAGATCTGCAGTTAGCAGAATCTGAGCAGTCTTTGCGGGAGCTGCAGTTTTGTACATATGATGGGGTTTTCATTTGGAAAATTGCAGAATTCTCTCGACGCAGGCAAGACGCAGTGGCAGGCCGAGCACCTGCCATGTTCTCACCTGCATTTTACTCCAGTAAATATGGGTATAAGATGTGTCTGAGACTGTACCTGAACGGTGATGGCACAGGTCGAGGCTCTCATCTCTCTCTGTTCTTTGTGGTCATGAAAGGCAAATATGATGCTCTGCTGAAGTGGCCCTTCAGCCAGAAGGTGACATTGATGCTGTTGGACCAAAATAACAGAGAGCACATCATTGATGCCTTCAGGCCTGACGTGAGCTCCACATCTTTCCAGAGACCCATCAGTGAGATGAATATAGCCAGTGGCTGTCCTCTCTTCTGCCCCCTCGCCAAGCTGGCAGGCAAAAGCTCATATCTGAGAGACGACACCATATTTATTAAAGCCATAGTCGACCTTACTGGCTTATAAGACCAAATAGATCACTCATAATAACAATTTATGATATTATTGTGCTGCGGAAGACACATATTTGAAATATTacataatagaaataataatataaaggatAATATCATggttattatgatttttataaacattatttttattattatcatattgaaaacATTTAAGGTTCTAGAACTTAATGTTTTAACTATACTAGTAGATTACTTGCATTATTATAATCCAAAGATTtgcttattaacattagttaatacacaAGAACTAACAAGGAACAACCTTATTTCAATTAACTAACGTAAACACCGGTGAATAAATACAgcaatgtattgttcattgttggtTCATGTTTGGTAATATATTACAAGAAGGTTCCAATAGTTCATGTTAAACTGTTACCttaagtgttattattattattattatttattatatgcaaaatGATAATGTTGTAAAGAGACATCCACACCAATAATTGCACTATTGTGAtataattgaatatttaata

Function

symbol description
traf2b Predicted to enable tumor necrosis factor receptor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within several processes, including activation of NF-kappaB-inducing kinase activity; protein autoubiquitination; and regulation of JNK cascade. Predicted to be located in cytosol. Predicted to be active in cytoplasmic side of plasma membrane. Orthologous to human TRAF2 (TNF receptor associated factor 2).

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0070534 protein K63-linked ubiquitination biological_process
GO:0007250 activation of NF-kappaB-inducing kinase activity biological_process
GO:0046328 regulation of JNK cascade biological_process
GO:0046330 positive regulation of JNK cascade biological_process
GO:0033209 tumor necrosis factor-mediated signaling pathway biological_process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biological_process
GO:0051865 protein autoubiquitination biological_process
GO:0007165 signal transduction biological_process
GO:0009898 cytoplasmic side of plasma membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0098802 plasma membrane signaling receptor complex cellular_component
GO:0046872 metal ion binding molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0005164 tumor necrosis factor receptor binding molecular_function
GO:0031625 ubiquitin protein ligase binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-5345 Predicted to enable tumor necrosis factor receptor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within several processes, including activation of NF-kappaB-inducing kinase activity; protein autoubiquitination; and regulation of JNK cascade. Predicted to be located in cytosol. Predicted to be active in cytoplasmic side of plasma membrane. Orthologous to human TRAF2 (TNF receptor associated factor 2).

Ensembl:

ensembl_id ENSDARG00000101036

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00059520 False 1638 mRNA 0.47 11 54422941 54453346
TCONS_00059521 False 1829 mRNA 0.46 11 54424592 54453346
TCONS_00059522 True 2135 mRNA 0.41 11 54424613 54453848

Neighbor

gene id symbol gene type direction distance location
XLOC_030462 bspry coding upstream 7877 54400971 ~ 54415064 (+)
XLOC_030461 rangrf coding upstream 128855 54280135 ~ 54294086 (+)
XLOC_030460 CR450749.2 coding upstream 314427 54106010 ~ 54108514 (+)
XLOC_030459 naa38 coding upstream 514267 53876169 ~ 53908674 (+)
XLOC_030458 sat2b coding upstream 557485 53824959 ~ 53865456 (+)
XLOC_030464 NA coding downstream 27911 54481759 ~ 54482867 (+)
XLOC_030465 tmem203 coding downstream 43627 54497475 ~ 54499117 (+)
XLOC_030466 tprn coding downstream 47257 54501105 ~ 54542062 (+)
XLOC_030467 anapc2 coding downstream 101719 54555567 ~ 54580564 (+)
XLOC_030468 npr2 coding downstream 127114 54580962 ~ 54661956 (+)
XLOC_030455 NA non-coding upstream 1230136 53191662 ~ 53192805 (+)
XLOC_030454 NA non-coding upstream 1231874 53188004 ~ 53191067 (+)
XLOC_030449 BX957336.2 non-coding upstream 1980449 52438392 ~ 52442492 (+)
XLOC_030448 FP016029.1 non-coding upstream 2197136 52225684 ~ 52225805 (+)
XLOC_030470 NA non-coding downstream 257175 54711023 ~ 54711655 (+)
XLOC_030472 NA non-coding downstream 611934 55065782 ~ 55074200 (+)
XLOC_030473 CU207241.1 non-coding downstream 665662 55119510 ~ 55123220 (+)
XLOC_030474 NA non-coding downstream 680757 55134605 ~ 55140137 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000059_00293442_00308109 TRAF2B, TRAF2 coding CI01000059 null 293442 ~ 309217 (+)