XLOC_004133 (trib3)


Basic Information

Item Value
gene id XLOC_004133
gene name trib3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 24058530 ~ 24063196 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00007897
GACACAACTAAGTGCGCCTGTAGTTTTCATTGTTCTGTTTTGGAGAGGAGCGGGTCCTTTGTCTAAAGCAGCGAGATGAGTATGAACCTGTCAACTCCTACACCTCCACTGCGACTGAAGCGAGTTGACTTTGAGGACTCTCACAGCAATGATACCTTCAAATGCAAGCGCCGTAGACTCAGTCAGCCTCCTTCCCCAGGTCTTGCGCCCTGCCTTCGCCCCCTGTCACAAAGCCTTGAACAGCCAGGGTCTGAAAAGCACCACGTCTCCCGGATCGGACCATACATCCTCCTGGAGGCCACAGAAGTAGCTCAAACCTTCAGAGCGGTTCATCAGGTCACAGAACAGGAATACACATGCAAAGTGTTTTCCATGAAGAAGTATCATGAGTTCATTGCGCCCTACACTCGTCTGCTTCCACACAGCAACATCTGCAAGATTTCAGAGGTGGTGTTAGGGGAAAACAACGTGTACATCTTTTTCGAGCGCAATTATGGAGACATGCATTCGTATGTGCGCACCTGCAAGCGGTTGCAGGAGGACGAGGCTGTGCGTCTGTTCACTCAGATGGCATCAGCTGTAGCACACTGTCATGAGAACGGTGTCATTTTACGAGACCTCAAACTACGCAAGTTTGTGTTCACCGATCAGCAGAGAACAAAGCTGGTCTTGCAAAACCTGGAGGACTCTTGTCTGCTAAACGGAAATGACGACTCGCTGACGGACAAACACGGCTGCCCGGCTTACGTCGGCCCGGAGATCTTAAACTCACGTCACTCATACTCAGGAAAGGCTGCTGACGTTTGGAGCCTCGGCGTGGTTCTTTACACCATGCTTGTAGGACGTTACCCATTTCAGGATGTGGAACCGACAGCACTGTTCAGCAAAATCCGCAGGGGTGCATTCACCGTCCCAGAGACCCTCTCCCCCCGGGCTAAGTCGCTGGTGTACTGCATGTTAAGGAAATGTCCATCAGAGAGGCTGGAGGCCGGAGATATACTTCTCCATCCGTGGCTTCACTGTAATAACAGCACATCTCTTAGTCAGCACTCCAGCTCCAGACACTCCACAGATCAGGTGGTTCCTGATTTCCAACCCAGCCAGACTGAGGACTGTCAGTGAGCTGCTTTCATTATGTTTACCCACAATCAGGCGGGAAAAAGACTCTATGGAAAAGAGAGATTGCCTCATATTAAGTATGCAGAGTTCAAGGGCATCCAATGGAACAGATCCTCAAACATGTGCAGGTTAATAGCAGTGCTGTGTTTcgtttttttacatttctgcCCAGCAATGAACTGCTGAGGTGTTCAGGACTGACACTGAGTCTTTATAGAAAGAATTAACTGTGTTTCTTACCTCTGAAACTGGCAATTTCTCCAAGAAAACGACACCCGAAGGGCGAAGTGCTGCTGGTTAAACTCTTTTTCTGGTAGACTTTCATTCACAGCACAGCTTAGAGGCTTGTGCACCATTGAACATCAGTGTTGCTTAATAATCAGTGCATGGATTTTCCATTGTACACctttgttgtgtaaaaaaaagtaCCTCTAACTTAATTCCTGGTATACTTGATGCACAGTTCGTGCCTTTATGTACtgtttacatatttttgcagTGGAGAAAAACAAACAGATTTGACTATTTAAAGTGCCTTTTTTTCCAGTTGTTGGACTTGTTGAAGTACCAAAGATTTgagttgggttttttttttcgtCATCCAAATCTGAGCGTGTGTATCTGCAACGGGTTAGCACAAGTGCTCATTTCCTTTTCATGTGAAGAATACAAAAgggttgcttgtttgtttgttttttccagcAAATTCTCTTTTGTAAATGTCTTTCCATCTGTTAAACGTATGTATTTAGTGCTGTAGAGCAGGTTTGACCCTGATGGGATGTGAGCACATCATGCAACACAGGAAACGTCCCATGTGATGGTTTAGAGGTGCACCTGTCGTGCGTAAACAAAGGCTTTACATTCGTTCTCGTTTGTGATGCCTGCATGCAATGCTTtgaccctgtttttttttttcattcaagtaCTTGTCATTTTTCTGTAGATAATTTTTGTTAATAACGAGAAGTGTACactacatttgttgttgtttcaaGGGGTGATGTACCTACAAGCGAGTATTTTGTTGTTGCcagtacaaataaaatgaaaaatcagAA

Function

symbol description
trib3 Predicted to enable mitogen-activated protein kinase kinase binding activity. Acts upstream of or within heart looping. Predicted to be active in nucleus. Is expressed in several structures, including axial mesoderm; central nervous system; intestine; noninvoluting endocytic marginal cell cluster; and notochord. Orthologous to human TRIB3 (tribbles pseudokinase 3).

GO:

id name namespace
GO:0043405 regulation of MAP kinase activity biological_process
GO:0006468 protein phosphorylation biological_process
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0001947 heart looping biological_process
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0003714 transcription corepressor activity molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0031434 mitogen-activated protein kinase kinase binding molecular_function

KEGG:

id description
ko04931 Insulin resistance
ko01001 Protein kinases

ZFIN:

id description
ZDB-GENE-040426-2609 Predicted to enable mitogen-activated protein kinase kinase binding activity. Acts upstream of or within heart looping. Predicted to be active in nucleus. Is expressed in several structures, including axial mesoderm; central nervous system; intestine; noninvoluting endocytic marginal cell cluster; and notochord. Orthologous to human TRIB3 (tribbles pseudokinase 3).

Ensembl:

ensembl_id ENSDARG00000016200

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00007897 True 2180 mRNA 0.45 4 24058530 24063196

Neighbor

gene id symbol gene type direction distance location
XLOC_004132 chia.3 coding downstream 41717 24013769 ~ 24016813 (-)
XLOC_004131 CR354444.1 coding downstream 157169 23900000 ~ 23901361 (-)
XLOC_004129 pik3c2b coding downstream 361313 23593837 ~ 23697217 (-)
XLOC_004130 LO016980.1 coding downstream 403052 23655350 ~ 23655478 (-)
XLOC_004128 plekha6 coding downstream 532919 23342996 ~ 23525611 (-)
XLOC_004134 sox12 coding upstream 124414 24187610 ~ 24191928 (-)
XLOC_004135 si:ch211-15p9.2 coding upstream 282501 24345697 ~ 24347644 (-)
XLOC_004136 dvl1b coding upstream 297548 24360744 ~ 24428319 (-)
XLOC_004137 mxra8a coding upstream 366727 24429923 ~ 24458786 (-)
XLOC_004138 plekhg5a coding upstream 401160 24464356 ~ 24538860 (-)
XLOC_004063 CR854846.1 misc downstream 7930852 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 11366839 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 11436763 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 11467234 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 11545268 12512966 ~ 12513262 (-)
XLOC_004125 BX571675.2 non-coding downstream 749212 23305755 ~ 23309318 (-)
XLOC_004123 CR555297.1 non-coding downstream 899223 23159189 ~ 23159307 (-)
XLOC_004117 NA non-coding downstream 1964133 22089435 ~ 22094397 (-)
XLOC_004140 NA non-coding upstream 646588 24709784 ~ 24714293 (-)
XLOC_004141 CR628365.1 non-coding upstream 756069 24819265 ~ 24820001 (-)
XLOC_004142 CR628365.2 non-coding upstream 904575 24967771 ~ 24967887 (-)
XLOC_004144 dre-mir-499 non-coding upstream 1141957 25205153 ~ 25205243 (-)
XLOC_004147 NA non-coding upstream 1304916 25368112 ~ 25408896 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000306_02244385_02249335 TRIB3 coding CI01000306 null 2243388 ~ 2249335 (-)