XLOC_005743 (pde10a)


Basic Information

Item Value
gene id XLOC_005743
gene name pde10a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 4505079 ~ 4620715 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011371
CGGGGTGGAGATACGCGAACGCCGCCGCTCTCAGAGCCATTCTCCGGCTCCACAATAGACGAGTTCTCAtcgccttttgtttttgttaacattatattagGAGGAGAGGACAGGGGCGCCGTCTACATACTGGACACACAGACGCTTGAGCGCGCGTAAAACACGGCGTTCTAGAACGTCTTCCAATCTTGACGCGCTTTGATGTCATCCGGCGTGTCAGGGTCGGATCGCTTCATTTATAGCAGCGGGTCGACATTAAACTAGACGCAGATCACATCCAGAGTTATCCCTACTCGCTGGCGGTCAGACATGGAAGATGGTCCGCCTTCCACAAGCTGTTTCCGAAGGTTCACGGACTGTTTCCTTGGCTCAAGTCTGACGGATGAGAAAGTGAAGGCTTATCTCTCCCTCCACCCGCAGATGCTGGATGAGTTTGTGCTGGAGAGCGTGAGCTCGGAGACGGTGGACAGATGGCTGAAGCGGAAGAGCAGCACTCAGCCTGCAGATGACTCCTCAGCTAAAGAAGTTAGCAGGTACCAGGACACAAATATGCAGAGCGTCGTTTATGAGCTCAACAGCTACATGGAGCAGCGGCTGGACACTGGAGGAGACAACAAACTACTGCTCTATGAGTTGTGCAACATCATTAAAACAGCCACTAAAGCTGACGGATTTGCACTTTACTTCCTTGGAGAATGCAACAATAGTTTATGTTTGTTCACTCCGACGGGGGCAAAAGAGGGGCTTCCTGGGCTCATCCCCTCTGGTCCCATTACGTTTGGGACCACCATCGCCGCTCACGTTGCAAAGACACGCAAGACACTACTTGTAGAGGACATCATGGGGGACGAGAGGTTCCCTCATGGCACAGGGCAGGACTCAGGGATCCGTGTTCattctgttttgtgtttacccaTCCTCACCGCCATCGGAGACCTCATCGCTATCCTGGAGCTGCACCGCCACTTGGGTCGAGAGCCCTTCAACCTCAGCCACCAGGAGgttGCAACAGCAAATTTGGCCTGGGCATCTGTAGCCATACACCAAGTCCAGGTCTGCAGAGGTCTTGCCAAACAGACGGAACTCAATGACTTTCTCCTAGATGTGTCAAAAACATACTTTGACAACATAGTGGCAATAGATTCTCTACTTGAACATATCATGATATATGCAAAAAACCTGGTTAATGCGGACAGATGTGCGCTCTTCCAGGTGGATCACAATAACAAagagctgtattctgatctgtttGATATCGGGGAGGAGAATGAAGGGAAACCTGTCTTCAGGAAAACCAAAGAAATTAGGTTTTCGATTGAGAAAGGAATAGCAGGTCAAGTGGCCCGAACAGGAGAAGTTTTGAATATTCCGGATGCCTATGCAGACCCCCGTTTCAACAGAGAAGTAGATCTCTACACTGGCTACACGACGCGGAATATCCTGTGCATGCCCATAGTCAGCCGCGGGACTGTGATCGGTGTTGTACAAATGGTGAACAAGCTGGGAGGAAGTGCCTTCACTAAAACTGACGAGAACAACTTTAAGATGTTCGCCGTCTTCTGTGCTTTGGCCTTACACTGTGCAAATatgTATCACCGGATAAGACATTCAGAGTGCATTTACCGGGTGACCATGGAGAAGCTTTCGTACCACAGCATCTGTACGTCAGAGGAGTGGAAGACCCTCACTCAACTCACCCTCCCTTCAGCCATATATAAAGAGATCGAACTGTTTCACTTTGACATTGCACCGTTCGAGGAGCTGTGGCCTGCAATATTCGTATACATGGTTCATAATTCATGTGGAAAAACCAGCTTTGAGTTGGAGAAACTGTGCCGCTTCACTATGTCAGTGCGGAAAAATTACAGAAGAGTTCCATACCACAACTGGAAACATGCTGTGACGGTGGCACACTGCATGTACGCCATTTTGCAAAAGACCACTGGGATTTTTACTGAGCTTGAGAGGAAAGGGTTGCTGATTGCCTGTTTATGTCATGACCTGGACCACCGCGGCTACAGTAACAGTTACCTGCAGAAGTTTGACCATCCGCTGGCAGCCCTGTATTCCACATCCACCATGGAACAGCATCATTTTTCACAGACCGTGTCCATCCTGCAGCTGGAAGGGCACAATATTTTCTCCAACCTGACTTCCGGTGAGTATGAACAGGTGCTGGAGATCATCAGGAAGGCCATCATTGCCACAGACCTCGCTCTGTACTTCGGCAACCGCAAGCAGCTGGCTGAACTGCTGTCTACAGGGGCGCTCGACCTGAACAACCGCGCTCACAGGGACcgtgtgattggtctgatgatgACCGCCtgtgatctctgctctgttacCAAATTATGGCCCGTCACAAGACTCACAGCCAATGACATCTACGCCGAGTTCTGGGCTGAGGGAGATGAAATGAAGAAGATTGGAATGCAGCCTATCTCCATGATGGACAGGGATAAAAAGGATGAGGTACCCCAGGGCCAGGTGGGGTTTTACAATGCAGTGGCTATTCCCTGTTACACCACTCTGTCTGAGCTGTTTCCTCCCTCCGTTCCTTTGCTTGAAGCTTGCAG
>TCONS_00011372
GCGTAAAACACGGCGTTCTAGAACGTCTTCCAATCTTGACGCGCTTTGATGTCATCCGGCGTGTCAGGGTCGGATCGCTTCATTTATAGCAGCGGGTCGACATTAAACTAGACGCAGATCACATCCAGAGTTATCCCTACTCGCTGGCGGTCAGACATGGAAGATGGTCCGCCTTCCACAAGCTGTTTCCGAAGGTTCACGGACTGTTTCCTTGGCTCAAGTCTGACGGATGAGAAAGTGAAGGCTTATCTCTCCCTCCACCCGCAGATGCTGGATGAGTTTGTGCTGGAGAGCGTGAGCTCGGAGACGGTGGACAGATGGCTGAAGCGGAAGAGCAGCACTCAGCCTGCAGATGACTCCTCAGCTAAAGAAGTTAGCAGGTACCAGGACACAAATATGCAGAGCGTCGTTTATGAGCTCAACAGCTACATGGAGCAGCGGCTGGACACTGGAGGAGACAACAAACTACTGCTCTATGAGTTGTGCAACATCATTAAAACAGCCACTAAAGCTGACGGATTTGCACTTTACTTCCTTGGAGAATGCAACAATAGTTTATGTTTGTTCACTCCGACGGGGGCAAAAGAGGGGCTTCCTGGGCTCATCCCCTCTGGTCCCATTACGTTTGGGACCACCATCGCCGCTCACGTTGCAAAGACACGCAAGACACTACTTGTAGAGGACATCATGGGGGACGAGAGGTTCCCTCATGGCACAGGGCAGGACTCAGGGATCCGTGTTCattctgttttgtgtttacccaTCCTCACCGCCATCGGAGACCTCATCGCTATCCTGGAGCTGCACCGCCACTTGGGTCGAGAGCCCTTCAACCTCAGCCACCAGGAGgttGCAACAGCAAATTTGGCCTGGGCATCTGTAGCCATACACCAAGTCCAGGTCTGCAGAGGTCTTGCCAAACAGACGGAACTCAATGACTTTCTCCTAGATGTGTCAAAAACATACTTTGACAACATAGTGGCAATAGATTCTCTACTTGAACATATCATGATATATGCAAAAAACCTGGTTAATGCGGACAGATGTGCGCTCTTCCAGGTGGATCACAATAACAAagagctgtattctgatctgtttGATATCGGGGAGGAGAATGAAGGGAAACCTGTCTTCAGGAAAACCAAAGAAATTAGGTTTTCGATTGAGAAAGGAATAGCAGGTCAAGTGGCCCGAACAGGAGAAGTTTTGAATATTCCGGATGCCTATGCAGACCCCCGTTTCAACAGAGAAGTAGATCTCTACACTGGCTACACGACGCGGAATATCCTGTGCATGCCCATAGTCAGCCGCGGGACTGTGATCGGTGTTGTACAAATGGTGAACAAGCTGGGAGGAAGTGCCTTCACTAAAACTGACGAGAACAACTTTAAGATGTTCGCCGTCTTCTGTGCTTTGGCCTTACACTGTGCAAATatgTATCACCGGATAAGACATTCAGAGTGCATTTACCGGGTGACCATGGAGAAGCTTTCGTACCACAGCATCTGTACGTCAGAGGAGTGGAAGACCCTCACTCAACTCACCCTCCCTTCAGCCATATATAAAGAGATCGAACTGTTTCACTTTGACATTGCACCGTTCGAGGAGCTGTGGCCTGCAATATTCGTATACATGGTTCATAATTCATGTGGAAAAACCAGCTTTGAGTTGGAGAAACTGTGCCGCTTCACTATGTCAGTGCGGAAAAATTACAGAAGAGTTCCATACCACAACTGGAAACATGCTGTGACGGTGGCACACTGCATGTACGCCATTTTGCAAAAGACCACTGGGATTTTTACTGAGCTTGAGAGGAAAGGGTTGCTGATTGCCTGTTTATGTCATGACCTGGACCACCGCGGCTACAGTAACAGTTACCTGCAGAAGTTTGACCATCCGCTGGCAGCCCTGTATTCCACATCCACCATGGAACAGCATCATTTTTCACAGACCGTGTCCATCCTGCAGGAAGGGCACAATATTTTCTCCAACCTGACTTCCGGTGAGTATGAACAGGTGCTGGAGATCATCAGGAAGGCCATCATTGCCACAGACCTCGCTCTGTACTTCGGCAACCGCAAGCAGCTGGCTGAACTGCTGTCTACAGGGGCGCTCGACCTGAACAACCGCGCTCACAGGGACcgtgtgattggtctgatgatgACCGCCtgtgatctctgctctgttacCAAATTATGGCCCGTCACAAGACTCACAGCCAATGACATCTACGCCGAGTTCTGGGCTGAGGGAGATGAAATGAAGAAGATTGGAATGCAGCCTATCTCCATGATGGACAGGGATAAAAAGGATGAGGTACCCCAGGGCCAGGTGGGGTTTTACAATGCAGTGGCTATTCCCTGTTACACCACTCTGTCTGAGCTGTTTCCTCCCTCCGTTCCTTTGCTTGAAGCTTGCAGGGAAAACCTGTCCCAGTGGGAGCGCATTGTGCAAGGGGAGGACGTCTCTGCGTGGTCATCAACCGAGGAGGCTGAAGTGAGCGAAACATCAGACAGTGGACCAGTTAAAGTGGACAACTGAATCTGTGGCACCTTTCCCACAGCACCACCCACAACCTGCCAGAGACACTGGACTTCCTGTGGACAGTCCCACTTCCTGCAGAGACGGGAGGAAGTGCAGAGGGCAGGCGGACGAGgatactttcagaaaaaaaataaacaaaacataatgtTACCTCAGCGGGTGATGGAGGCGCACACTCTAATGACATCAGGGCTCCCTTGTTGATGGCTGGGACTCAAGTCCGGTTCAGCAGAATGGGCGTCATTATTGGCAGTACTTTCCCTTAAGAGGTTGCTTTCTTTTAGGctttctttttcagtttatttcgtGGTCTTACGTTTTGAAGAGGCCTTAAAAACGAACCCGAGTTACGATCTGACTCGTAACCAGAAGACGGTTCGTCTAGTTTAATATGGTACATTTTATCCTGCTGTGGTCGAAAACGTTGTACGCGAA

Function

symbol description
pde10a Predicted to enable cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cGMP-mediated signaling and signal transduction. Is expressed in chordo neural hinge; epidermis; nervous system; and notochord. Orthologous to human PDE10A (phosphodiesterase 10A).

GO:

id name namespace
GO:0010754 negative regulation of cGMP-mediated signaling biological_process
GO:0007165 signal transduction biological_process
GO:0046872 metal ion binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity molecular_function
GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity molecular_function
GO:0008081 phosphoric diester hydrolase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1115 Predicted to enable cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cGMP-mediated signaling and signal transduction. Is expressed in chordo neural hinge; epidermis; nervous system; and notochord. Orthologous to human PDE10A (phosphodiesterase 10A).

Ensembl:

ensembl_id ENSDARG00000003449

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011371 False 2576 mRNA 0.50 21 4505079 4615216
TCONS_00011372 True 2979 mRNA 0.50 22 4505232 4620715

Neighbor

gene id symbol gene type direction distance location
XLOC_005742 tbxtb coding upstream 51416 4439074 ~ 4453663 (+)
XLOC_005741 si:ch211-130h14.4 coding upstream 66039 4409294 ~ 4439040 (+)
XLOC_005739 NA coding upstream 96123 4398151 ~ 4408956 (+)
XLOC_005740 prr18 coding upstream 98005 4405282 ~ 4407074 (+)
XLOC_005738 sft2d1 coding upstream 104263 4368504 ~ 4400816 (+)
XLOC_005745 NA coding downstream 20590 4641305 ~ 4666921 (+)
XLOC_005746 pla2g12b coding downstream 50983 4671698 ~ 4683595 (+)
XLOC_005747 NA coding downstream 90554 4711269 ~ 4721332 (+)
XLOC_005748 micu1 coding downstream 251171 4871886 ~ 4969687 (+)
XLOC_005749 mrps6 coding downstream 374718 4995433 ~ 5000739 (+)
XLOC_005737 NA non-coding upstream 169177 4332745 ~ 4335902 (+)
XLOC_005734 NA non-coding upstream 313043 4181231 ~ 4192036 (+)
XLOC_005733 NA non-coding upstream 370966 4133743 ~ 4134113 (+)
XLOC_005732 NA non-coding upstream 519399 3979927 ~ 3985680 (+)
XLOC_005751 NA non-coding downstream 502715 5123430 ~ 5129369 (+)
XLOC_005752 CR788226.1 non-coding downstream 776826 5397541 ~ 5401220 (+)
XLOC_005753 NA non-coding downstream 785435 5406150 ~ 5411457 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000005_01587815_01629740 PDE10A coding CI01000005 null 1587698 ~ 1629870 (+)