XLOC_005750 (psap)


Basic Information

Item Value
gene id XLOC_005750
gene name psap
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 5004924 ~ 5028964 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011381
ATAAAGCCTCATCACACGACCTCGCGACTCACTGCAGCATAAACAACACCATCACCCGAACAAGATTACTCTCAAAACGCGACACCGAGGTCAGACACAAGCGGTTCCTGAAGTCATGATGCTTCTCACGCTTCTTTTGGTCACCACAGCTGTGGCAAGTCCCCTGTTGGGAACGGAGCAGTGTGCCCGTGGTCCCCCCTACTGGTGCCAGAATGTCAAGACCGCTTCCCTTTGTGGTGCTGTCCAACACTGCCAACAGAATGTGTGGAACAAGCCTCAGATGAAAACTGTGCCATGTGATTTGTGCAAAGAGGTGTTGGTGGTAGTGGAGCAGCTGCTGAAGGACAATGTAACCGAGAGCGAACTCCTCGGGTATTTGGAGAAGGCATGTCAGCTGATCCCTGATGAAGGCCTGGCTAACCAGTGCAAGGAGATTGTGGACAACTACTTCCCAGTTCTCATGGGCATCATCCAAGGAGAGCTGGATGACCCTGGTGTAGTGTGTGGCGCTTTGGGTCTGTGCGTATCCCAGCAGGCAGCTCTGGCTAAAGCTCAGCTCACTTCCAACGAGATCCCTCAAGTGGACCTGAATCAGCGCGTCAGCCCCTTCCTGCTGAACATCCCACAGCTGCTCTATCCTGAAGAGAAAAGAGAGACCCCTAAACAGAAAGGTGATGTGTGCCAGGACTGCGTTACGTTCATCAATGACACTCAGGATGAAGCCAGAGTCAATTCTTCCTTTATCAGCACTCTGATTGCACAGGTGGAGAACCAGTGTGAGCTTCTGGGACCTGGAATGTCTGATATGTGCAAGGAGTACATCAGCCAGTACGGGCCTTTGGTCTTCCAGCAGCTCATGTCTATGCAACCCAAGGACATCTGTGCTCGCGCTGGCTTCTGCCCTACTAAACAAAAGTCTGTGCCCATGGAGAAGCTGCTGCCTGCCAAATCCATCCCTGCTGTCAAGATGTTCCCTGCGGTTAAAGTTGAGAAACCGGTTGCGACCATGCCTGCTAAGAACCTGGTGCGTGTGCGTGACTCTCCTCAGTGTGCCATCTGTGAATATGTGATGAAGGAAATTGAGAACATGATTCAGGATCAGACCTCTGAGGCAGAGATCGTGCAGGCTGTGGAGAAGGTCTGCAACATTTTGCCCTCCACACTCACGGCTCAGTGCAAGGACCTGATTGAAACCTACGGCCAGGCCATCATCGATCTCCTTGTGCAGGAGGCCGATCCCAAAACGGTCTGCTCTTTCCTTGCACTCTGCAGTGGGGTCAGCCATGTCCCTGTAATGGATAAGCAGCATTTCGCAGCAGGTGGTTTCTGTGATGTGTGCAAGATGGCTGTGCGCTATGTGGACGGGATCCTGGAGCAGAACGCCACTCAGTCTGAGATCGAGGAGGCCGtgctgaaagtctgcagcttccTGCCTGACGCCGTCAAAGATGAGTGCAACCAGCTGATTGAGCAGTACGAGCCTCTGCTGGTGCAGCTGCTGCTTCAGACCCTCGACCCTGACTTTGTCTGCATGAAGCTGGGAGCATGTCCTGAGGCCGTGCAGAGGCTGCTGGGATTAAATCAGTGCAGCTGGGGGCCTGCATACTGGTGTAAGAACGTGCAGACCGCCGCTCGCTGTAACGCCCTGAACCACTGCAGGCGTCACGTTTGGAGCTAAAGCGCGAGCAGAATACTTCCAGAACAATCTTAGGAAACTAAAGGAGAATTGCTGTAGAGCTGCGTTTCTGTTTCAAAATCAATACTtgggttttctttttaaaaaagtgactttaatcATTTGAATGGTCACCGCTAATTTAACCTTTGTTCAGGGGGAAGAAAGCTTTTACTGAGAGGATGCGTGCGCACACACTTATGAGGGGGGCAGGGTACGACTGGCAGGTGTAGCTATTTGTGAAATACTTGCACTGagctttttgtttagttttgtgtgtgCTAATgtgaagacttttttttaattttaatttttagagTTGATGTTAGTCGTATGTTTCTTCAAATATGCACCCGAGAGAGTTTATATGGACATAGATTGTGCCTTTAACTGGAAAGGAGGTCTGAGACCCCCCCCTTGGAACGATGCTTTAGGATGCTGTAATCTCCCTGCCTCCCTCTTTAACTGCTAATACACCTGCAAGGCCAGTGAtgtaaacatttctgtttttaatgGGTGATGTTTTTGGTCCTAATGGTTGTCGATTCTGTCATTGTGCTTCTTTAATGATTTGGAGGAGGGGAAGGTGATGCTGACGTTCATTATTTGATCCACTGATTGTTGCCCCTCAGTGATTTGATCGCTCTCACTTCCTAAATGTCAGATTTTCTTTCCACTGTTCAGACTgaggctgtttttaaaaaaaattacaaattaaaccgACTTAAACCCCG
>TCONS_00011382
ATGATGCTTCTCACGCTTCTTTTGGTCACCACAGCTGTGGCAAGTCCCCTGTTGGGAACGGAGCAGTGTGCCCGTGGTCCCCCCTACTGGTGCCAGAATGTCAAGACCGCTTCCCTTTGTGGTGCTGTCCAACACTGCCAACAGAATGTGTGGAACAAGCCTCAGATGAAAACTGTGCCATGTGATTTGTGCAAAGAGGTGTTGGTGGTAGTGGAGCAGCTGCTGAAGGACAATGTAACCGAGAGCGAACTCCTCGGGTATTTGGAGAAGGCATGTCAGCTGATCCCTGATGAAGGCCTGGCTAACCAGTGCAAGGAGATTGTGGACAACTACTTCCCAGTTCTCATGGGCATCATCCAAGGAGAGCTGGATGACCCTGGTGTAGTGTGTGGCGCTTTGGGTCTGTGCGTATCCCAGCAGGCAGCTCTGGCTAAAGCTCAGCTCACTTCCAACGAGATCCCTCAAGTGGACCTGAATCAGCGCGTCAGCCCCTTCCTGCTGAACATCCCACAGCTGCTCTATCCTGAAGAGAAAAGAGAGACCCCTAAACAGAAAGGTGATGTGTGCCAGGACTGCGTTACGTTCATCAATGACACTCAGGATGAAGCCAGAGTCAATTCTTCCTTTATCAGCACTCTGATTGCACAGGTGGAGAACCAGTGTGAGCTTCTGGGACCTGGAATGTCTGATATGTGCAAGGAGTACATCAGCCAGTACGGGCCTTTGGTCTTCCAGCAGCTCATGTCTATGGAACAGCAACCCAAGGACATCTGTGCTCGCGCTGGCTTCTGCCCTACTAAACAAAAGTCTGTGCCCATGGAGAAGCTGCTGCCTGCCAAATCCATCCCTGCTGTCAAGATGTTCCCTGCGGTTAAAGTTGAGAAACCGGTTGCGACCATGCCTGCTAAGAACCTGGTGCGTGTGCGTGACTCTCCTCAGTGTGCCATCTGTGAATATGTGATGAAGGAAATTGAGAACATGATTCAGGATCAGACCTCTGAGGCAGAGATCGTGCAGGCTGTGGAGAAGGTCTGCAACATTTTGCCCTCCACACTCACGGCTCAGTGCAAGGACCTGATTGAAACCTACGGCCAGGCCATCATCGATCTCCTTGTGCAGGAGGCCGATCCCAAAACGGTCTGCTCTTTCCTTGCACTCTGCAGTGGGGTCAGCCATGTCCCTGTAATGGATAAGCAGCATTTCGCAGCAGGTGGTTTCTGTGATGTGTGCAAGATGGCTGTGCGCTATGTGGACGGGATCCTGGAGCAGAACGCCACTCAGTCTGAGATCGAGGAGGCCGtgctgaaagtctgcagcttccTGCCTGACGCCGTCAAAGATGAGTGCAACCAGCTGATTGAGCAGTACGAGCCTCTGCTGGTGCAGCTGCTGCTTCAGACCCTCGACCCTGACTTTGTCTGCATGAAGCTGGGAGCATGTCCTGAGGCCGTGCAGAGGCTGCTGGGATTAAATCAGTGCAGCTGGGGGCCTGCATACTGGTGTAAGAACGTGCAGACCGCCGCTCGCTGTAACGCCCTGAACCACTGCAGGCGTCACGTTTGGAGCTAA
>TCONS_00011383
AGCTGTGGCAAGTCCCCTGTTGGGAACGGAGCAGTGTGCCCGTGGTCCCCCCTACTGGTGCCAGAATGTCAAGACCGCTTCCCTTTGTGGTGCTGTCCAACACTGCCAACAGAATGTGTGGAACAAGCCTCAGATGGCCTGGCTAACCAGTGCAAGGAGATTGTGGACAACTACTTCCCAGTTCTCATGGGCATCATCCAAGGAGAGCTGGATGACCCTGGTGTAGTGTGTGGCGCTTTGGGTCTGTGCGTATCCCAGCAGGCAGCTCTGGCTAAAGCTCAGCTCACTTCCAACGAGATCCCTCAAGTGGACCTGAATCAGCGCGTCAGCCCCTTCCTGCTGAACATCCCACAGCTGCTCTATCCTGAAGAGAAAAGAGAGACCCCTAAACAGAAAGGTGATGTGTGCCAGGACTGCGTTACGTTCATCAATGACACTCAGGATGAAGCCAGAGTCAATTCTTCCTTTATCAGCACTCTGATTGCACAGGTGGAGA
>TCONS_00011384
CTTTGGTCTTCCAGCAGCTCATGTCTATGGAACAGCAACCCAAGGACATCTGTGCTCGCGCTGGCTTCTGCCCTACTAAACAAAAGTCTGTGCCCATGGAGAAGCTGCTGCCTGCCAAATCCATCCCTGCTGTCAAGATGTTCCCTGCGGTTAAAGTTGAGAAACCGGTTGCGACCATGCCTGCTAAGAACCTGGTGCGTGTGCGTGACTCTCCTCAGTGTGCCATCTGTGAATATGTGATGAAGGAAATTGAGAACATGATTCAGGATCAGACCTCTGAGGCAGAGATCGTGCAGGCTGTGGAGAAGGTCTGCAACATTTTGCCCTCCACACTCACGGCTCAGTGCAAGGACCTGATTGAAACCTACGGCCAGGCCATCATCGATCTCCTTGTGCAGGAGGCCGATCCCAAAACGGTCTGCTCTTTCCTTGCACTCTGCAGTGGGGTCAGCCATGTCCCTGTAATGGATAAGCAGCATTTCGCAGCAGGTGGTTTCTGTGATGTGTGCAAGATGGCTGTGCGCTATGTGGACGGGATCCTGGAGCAGAACGCCACTCAGTCTGAGATCGAGGAGGCCGtgctgaaagtctgcagcttccTGCCTGACGCCGTCAAAGATGAG

Function

symbol description
psap Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and regulation of lipid metabolic process. Predicted to act upstream of or within sphingolipid metabolic process. Predicted to be located in extracellular region and lysosome. Predicted to be active in extracellular space. Is expressed in blood; extension; peripheral olfactory organ; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency and combined saposin deficiency. Orthologous to several human genes including PSAP (prosaposin).

GO:

id name namespace
GO:0019216 regulation of lipid metabolic process biological_process
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway biological_process
GO:0006629 lipid metabolic process biological_process
GO:0006665 sphingolipid metabolic process biological_process
GO:0005764 lysosome cellular_component
GO:0005615 extracellular space cellular_component

KEGG:

id description
ko00600 Sphingolipid metabolism
ko04142 Lysosome
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-020108-1 Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and regulation of lipid metabolic process. Predicted to act upstream of or within sphingolipid metabolic process. Predicted to be located in extracellular region and lysosome. Predicted to be active in extracellular space. Is expressed in blood; extension; peripheral olfactory organ; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency and combined saposin deficiency. Orthologous to several human genes including PSAP (prosaposin).

Ensembl:

ensembl_id ENSDARG00000013968

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011381 False 2409 mRNA 0.49 14 5004924 5028964
TCONS_00011382 False 1569 mRNA 0.54 15 5005039 5028233
TCONS_00011383 False 496 mRNA 0.54 4 5013572 5017722
TCONS_00011384 True 623 mRNA 0.54 6 5017864 5026221

Neighbor

gene id symbol gene type direction distance location
XLOC_005749 mrps6 coding upstream 4185 4995433 ~ 5000739 (+)
XLOC_005748 micu1 coding upstream 35237 4871886 ~ 4969687 (+)
XLOC_005747 NA coding upstream 283592 4711269 ~ 4721332 (+)
XLOC_005746 pla2g12b coding upstream 321329 4671698 ~ 4683595 (+)
XLOC_005745 NA coding upstream 338003 4641305 ~ 4666921 (+)
XLOC_005751 NA coding downstream 94466 5123430 ~ 5129369 (+)
XLOC_005752 CR788226.1 coding downstream 368577 5397541 ~ 5401220 (+)
XLOC_005753 NA coding downstream 377186 5406150 ~ 5411457 (+)
XLOC_005754 NA coding downstream 424148 5453112 ~ 5463881 (+)
XLOC_005755 NA coding downstream 460294 5489258 ~ 5558521 (+)
XLOC_005744 NA non-coding upstream 451254 4553392 ~ 4553670 (+)
XLOC_005739 NA non-coding upstream 595968 4398151 ~ 4408956 (+)
XLOC_005737 NA non-coding upstream 669022 4332745 ~ 4335902 (+)

Expression


Co-expression Network