XLOC_006407 (spred2b)


Basic Information

Item Value
gene id XLOC_006407
gene name spred2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 5870644 ~ 5937034 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012423
AACATGGAGTAATCAGAGATGGGGCTCGTCGGGGCCACCTCAGCTACAGCAACACTCCTTCCAGCTGCAGCGTTCTCGGAAATACACACAAGCACTCAAACCGGGGGAAACGATCCGAATTAAGGCTCTTTATTCCGAGATACTCCTCCATCAGCAACTGGTTAGGAAAAAAGgagtggaaaaaaaagaaaagaagcgaAAAAGCCATCAAGACGGAGACGAGGAGAGGAGAGGGAGCGACAAGAAGACAAACACACAGCCGAATGTGATGGATTATTTTGGGGGAAAAGAGTCTGGAGTGAGGCGTGAAGATGACGAACAGACCGAGCGGACCCGCTGTGGGATTTATGTGTAGGTGAAACGAGAAAAATGATTGAAGAAACACACCCAAACGAtgACAGTTACATTGTGCGCGTCAAAGCGGTGGTCATGACCCGAGATGACTCCAGTGGTGGATGGCTGGCACAGGAAGGTGGGGGGCTCAGCAGGGTGGGCGTCTGTAAGGTGATGCCTGCTGAGCTGACCGGCCGCAGCGACTTCCTCATCCACGGCGAGCGGCTCAAAGACAAGCAGGTGATTTTGGAATGTTTCGTGAGGAAAGACCTGATCTACACCAAGGCCACGCCCACATTTCACCACTGGAAGGTCGACAACAAAAAATGCGGCCTGACGTTCCAGAGCCCCGCCGATGCTCGTGCCTTTGACAGAGGAGTGCGGAAAGCCTTGGAGGACTTAACAGAGGgttCCACAACTTCCTCTTCAACACTCCAAAATGAGGCTGAACTTGGGGATGATGATGTGTTCACAACTGCCACCGACAGCTCCTCAAACTCATCTCAGAAGAAGGATCACAGCACTCAGCTTGTGGCCACCTCCACCTTCTACGAGCCTCATCCGCACCGCTGCATCCTGCAGTACCGGCCGCCTGAACGCTACACTCTGGATCAGAAGTTCTCTAGGAACCTGTTCTCCTTCGAGGACGAGGAGATTGTCCGAATAAACCCCCGCGAGCGCTGGATGATCACAGGCTATGAGGACTACCGATACGCTGCCGTGCCGGACAAGTTCATCCAACCGCAGGACTCAGACTCATATGTTCAAATCAGCAAGAACGATCCTGTAAAGCACGACTACACCTACCCCTATGTGCCCAGCCCCGATTTTACTCAGTGTGACCTGAAGAGGCCCTGCGGTGGTGGGAGCACTGTAGTGTCCACCCAGCCAAGGGCCTTCATCCTTAAAGGCAAGCGGAGGAAAGAGGACGGTGAGCGATCGCGCTGCGTCTACTGCCGGGACATGTTCAATCACGAGGAGAACCAACGCGGGCAGTGCCATGACGCTCCCGATCCCATCCGGACCTGCATCCACCGGGTCAGCTTCATGTGGTGCGCCGACAGCATGCTTTACCACTGCATGTCCGACCCAGAGGGCGACTACTCGGACCCATGCTCCTGCGACACCAGCGAGGAGCGCTTCTGCCTTCGCTGGACGGCTCTGCTGGGTCTGGCCATGCTTGCGCCCTGTCTGTGCTGCTACCCGCCGCTGCACGGGTGCCACCGCTGCGGGGTGGCCTGTGGCTGCTGCGGGGGAAAGCACAAAGCTGTGGGATGAAGCCCAAAATGACTCTAAACATGCCCCGCGTACGCCAGCACTGAGGAGCGCAGGAGTGGACCAAACCCAGAGCGACCACCCCGTTGTTGGAGCtttcactagctatgtttccatccacttattGTTATGCGCATCTTGGATTATCGCATGGATAACGTTTCGAAACGTTTGTAAAAAAACGTACAAACACAAATGAGTAggataaactatgatggaaacacttttaccgaataaatggacccttttcatattcccgggtttctcagtagcggaagttgTCATAGTTTatactggtttatacttctgcattgagtgatcggcatgacccacggcgcatTCCTTGCGCGATGCCATGCatgtatacttctgcgtgctgcttgtgttgctctgcagtaacacttctgaaacgctagcgctaggtttttatgttccgctgtgtcgagtttcttcgctggtgttctgttttttctgaacgctaccttaatgtacaagcagCTTAAATTCGcccattttgaggcaggaactggcggacgtgcaacaactttaatcataaggtaaacacaaaacaaaactttccatcaggagctccttcacaggactcaacactattaaacactcgctccaatgggTTTGCgtggctctcggccccgcccacactcgtcaacACTACCACGTACagcaatcacagagcttgcgctaatcgtcgttgtgacgtgtagttacactCTTTTGAGTGGTGTGCgtcggcgatggccacggcgagggctatgcgaacATGCGATGGCTGCACCGGAGCATACCcgtgtgcttgatgcagaagtataaatctgccTTTAGAATGCAGTGAATGGTAGagttcaacaaatatttttttacaatcctattttctgaaataataaaagaaaagctcCACGATGGCGTTATCaagatgctgcattagaaacaccccGCGTAAGCggtaattcgttttttgtaattgGACGCAAAGACGATGTAATACATACGTGaacatatataaatgtttatatcttAAAAGTTCTGACCCGTTAAACGCGTCTTGTGAAAAGGATGCCtttcagtattaaaaaaaattgtgcgcTATGCgtgtaaaaaatgtgtgtgtgacgcAATAATGGACAAACCTGCGACCgaaaacattgtaaaacatcggaaatgttgttttggtcattctgaaaTGCCCTAAATGCCATTTcagtatcatcatcattattatttttgttattattattattattattattgttattattattgttaaattattaattaactcCAGaaatgtcttgagcatctgtgtTTCGTGTCTCACGCCTCGAAATGCCACCACATGTCTATTGTGTGTTGACATTGTCTTTTGAggcacaagtaatttattaaattaagttcatttaaattaaa

Function

symbol description
spred2b Predicted to enable protein kinase binding activity. Predicted to be involved in negative regulation of peptidyl-threonine phosphorylation; positive regulation of DNA damage response, signal transduction by p53 class mediator; and regulation of protein deacetylation. Predicted to act upstream of or within regulation of signal transduction. Predicted to be located in plasma membrane and transport vesicle membrane. Is expressed in brain and spinal cord. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).

GO:

id name namespace
GO:0090311 regulation of protein deacetylation biological_process
GO:0007275 multicellular organism development biological_process
GO:0000188 inactivation of MAPK activity biological_process
GO:0009966 regulation of signal transduction biological_process
GO:0010801 negative regulation of peptidyl-threonine phosphorylation biological_process
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator biological_process
GO:0005886 plasma membrane cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0016020 membrane cellular_component
GO:0030658 transport vesicle membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0019901 protein kinase binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2342 Predicted to enable protein kinase binding activity. Predicted to be involved in negative regulation of peptidyl-threonine phosphorylation; positive regulation of DNA damage response, signal transduction by p53 class mediator; and regulation of protein deacetylation. Predicted to act upstream of or within regulation of signal transduction. Predicted to be located in plasma membrane and transport vesicle membrane. Is expressed in brain and spinal cord. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).

Ensembl:

ensembl_id ENSDARG00000008372

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012423 True 3030 mRNA 0.49 6 5870644 5937034

Neighbor

gene id symbol gene type direction distance location
XLOC_006406 NA coding downstream 138147 5730915 ~ 5732497 (-)
XLOC_006405 CR926469.1 coding downstream 246229 5579097 ~ 5624415 (-)
XLOC_006404 meis1b coding downstream 301082 5490551 ~ 5569562 (-)
XLOC_006403 NA coding downstream 383031 5480987 ~ 5487613 (-)
XLOC_006402 NA coding downstream 399055 5464154 ~ 5471589 (-)
XLOC_006408 actr2b coding upstream 9573 5946607 ~ 5978433 (-)
XLOC_006409 CABZ01033394.1 coding upstream 95810 6032844 ~ 6038477 (-)
XLOC_006410 dld coding upstream 138538 6075572 ~ 6081803 (-)
XLOC_006411 NA coding upstream 213187 6150221 ~ 6187744 (-)
XLOC_006412 CU984583.1 coding upstream 223547 6160581 ~ 6161564 (-)
XLOC_006338 rn7sk misc downstream 5044419 825904 ~ 826225 (-)
XLOC_006471 BX537274.2 misc upstream 4327707 10264741 ~ 10264905 (-)
XLOC_006401 NA non-coding downstream 474724 5390497 ~ 5395920 (-)
XLOC_006417 NA non-coding upstream 398330 6335364 ~ 6338658 (-)
XLOC_006419 NA non-coding upstream 1217288 7154322 ~ 7154837 (-)
XLOC_006421 NA non-coding upstream 1332178 7269212 ~ 7322676 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000005_02619187_02639895 SPRED2B, SPRED2 coding CI01000005 null 2618085 ~ 2639895 (-)