XLOC_006777 (srd5a2b)


Basic Information

Item Value
gene id XLOC_006777
gene name srd5a2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 35484229 ~ 35497586 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00013042
ATTAGGCTCATACCTGGTTTGAAAACGGACGGATACTCGACCTCCAATGCAGTGTCAGGAGCTCCTCGTGCGGGGCCTGAGTTTAGGGATGATCCTGGGTGGGGTAATGCACTTTATTTGTCTCATGAAGTCTCACGCTGCCTATGGCCGCTACGTGGACACCTCGGGCAGCTCCATGATGGTGCCCGCAAGGCTAGCGTGGTTCCTCCAGGAGATTCCAGCTTTACTGGTGCCCTTGCTTTTGATGATGACCACCGATGGAAACCAcggcactgggaaacacctgatGCTCTGGACCTTCTGCCTGCACTACTTCCAAAGGAGCTGTATCTACTCTCTGCTGACCAAAGGACGACCGTATCCATTTAACATCATGTTAACAGGGGTGGTGGTTTGCTCTATTAACGGCTTCCTGCAGGCACACTATCTGCTCCACTGTGCTACATTTCACAGCACATGGTTTTCTGATGCCTGTTTACTGACTGGTCTGATCATATTTTTCCTAGGAATGGGAATCAATATCCACAGTGACCACATTCTTCGAAACCTGAGAAACCCTGGAGAAATATCCTATAAAATCCCGAGAGGCGGCATGTTCGAGTACGTGTCTGGAGCAAATTTCTTCGGAGAGATAGTGGAGTGGCTGGGATACGCTGTTGCTACATGGTCTTTACCAACGTTCGCTTTTGCTTTTTTCACAATCTGCTTCATAGGCCCCAGAGCCTATCATCATCACAAGTAAACCGAAATTCATCAATTACTCAGAAATATACAAACTGCACTACTCTAACATGCTTTCATTTGGAATTTCGATTGATTCAGTAAATTGATTTTCGACAGTACAATGCCGGAAATAAATGTTAGAAGTGGTTACTCTAATCTCTTCCAGGTTTTATAATGAGAAGTTCAAAGATTTCCCCAGATCAAGAAGATCTCTCATTCCCTTCATCTTCTGAGGAGCCACAACGAATAAAATGAATTCATCTTCTCAACTGTTGCAATGAAGAGCTGTTCTTGGGGTTGTTTTCATTACCTGATTTACCATACATTATGAGGGAAATTCTGCCACATGTAGGAAAGTAACTAAAATGTATAACTCGAAAATGTAATGGTAAAGGATAAATCATATAACAGAATGTTTTATTACTTGCTTATATTTTGTTGCAGTTGTTAGTGTGAAACTGTGTCATCTTTTTGTGATAATTGTAAGTGGGTTGATTTCCCTAAACAGTGTCAATACTATGTGATGCTACAGTATTAAAACCTAAGCGTCTTAA

Function

symbol description
srd5a2b Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in hindbrain; pectoral fin; and testis. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0008202 steroid metabolic process biological_process
GO:0006694 steroid biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0047751 cholestenone 5-alpha-reductase activity molecular_function
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050417-182 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in hindbrain; pectoral fin; and testis. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2).

Ensembl:

ensembl_id ENSDARG00000039067

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00013042 True 1277 mRNA 0.43 4 35484229 35497586

Neighbor

gene id symbol gene type direction distance location
XLOC_006776 slx4ip coding downstream 11698 35391609 ~ 35472531 (-)
XLOC_006775 CU138575.1 coding downstream 113545 35370569 ~ 35370684 (-)
XLOC_006774 NA coding downstream 194792 35205297 ~ 35289437 (-)
XLOC_006773 CR932983.2 coding downstream 289470 35182994 ~ 35194759 (-)
XLOC_006772 btbd3b coding downstream 432332 35041892 ~ 35051897 (-)
XLOC_006778 memo1 coding upstream 13307 35510893 ~ 35527697 (-)
XLOC_006779 BX663524.1 coding upstream 94656 35592242 ~ 35592377 (-)
XLOC_006780 erlec1 coding upstream 253104 35750690 ~ 35765028 (-)
XLOC_006781 map3k4 coding upstream 290287 35787873 ~ 35844961 (-)
XLOC_006782 tacc3 coding upstream 382987 35880573 ~ 35892305 (-)
XLOC_006471 BX537274.2 misc downstream 25219324 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 34658004 825904 ~ 826225 (-)
XLOC_006769 BX649403.2 non-coding downstream 839948 34644150 ~ 34644281 (-)
XLOC_006768 BX649403.1 non-coding downstream 845483 34638629 ~ 34638746 (-)
XLOC_006784 NA non-coding upstream 427456 35925042 ~ 35925484 (-)
XLOC_006785 BX510990.1 non-coding upstream 464764 35962350 ~ 35962466 (-)
XLOC_006797 CR361558.1 non-coding upstream 901674 36399260 ~ 36399375 (-)
XLOC_006804 BX927407.1 non-coding upstream 1090184 36587770 ~ 36612159 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000012_05923216_05928055 SRD5A2B misc CI01000012 null 5922385 ~ 5929186 (+)