XLOC_016307 (ptgs2a)


Basic Information

Item Value
gene id XLOC_016307
gene name ptgs2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 20916497 ~ 20923864 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032144
AATACAACGGGCTCGACCAGAGTAACGCATCTCTGCTTCAACAGCCTCTAGATAATAACACTTCTGGAATGAATAAACTGGTTTGCTTGGTCCTACTTTCAAGCATTTGGATCTTTCCTGGTGAAGGATACGACCCTTGCTGTGCACAGCCTTGCCAAAACCAGGGCGTGTGTTTATCCAAGGGAGCTGATGCTTATGAATGTGACTGCACCAGGACAGGATATTATGGTGAAAACTGCACTACCCCTGAGCTTCTCACACGCATCAAATCAGCTCTGAAACCAAGACCAAATGTAGTGCATcatattttaacacattataaatcAATCTGGGATATCATCAACAGCATCTCTTACCTGAGGGATGGCATAATGCGCTATATCCTGTTGTCAAGGTCCCATTTGGTTgaaagtccaccgacgtacaatGCTGATTATGGCTACAAAAGCTGGGAAGCGTACTCTAATTTGTCCTATTACACCCGCACCCTTGCCCCGTTGCCCCAAAACTGCCCAACGCCTGATCTCCCAAATGCCAAGCAGGTGGTGGAGCAGGTGCTGTTGAGGAAGCAGTTCATCCCTGATCCACAGAGGAGCAGTCTCATGTTTGCTTTCTTCGCCCAGCATTTCTCTCACCAGTTCTTCAAGTCGGACTTTAAAAAGGGACCAGCCTTCACCAAAGCCCTGGGTCATGGAGTGGATCTGGGGCATATTTATGGAGAGACGCTGGAGGTTCAACACAAACTTCGTCTGTTTAAAGATGGAAAGCTTAAATACCAGGTTGTGGATGGTGAGGTGTACCCTCCGCTTGTGAAGGACGTCCAGGTGGAGATGCACTACCCTCCTCATATCCCGGAAGAGCAGAAATTTGCTGTGGGCCATGAGGCCTTTGGTCTGGTTCCAGGTTTGATAATGTATGCTACCATTTGGCTCCGTGAGCACAACCGTGTCTGTGACATCATGAAGCAGGAACATCCTGACTGGGATGATGAGAGAATCTTCCAAACCACTCGTCTCATCCTGATTGGTGAGACCATCAAAATTGTGATCGAGGACTATGTTCAGCACTTGAGTGGATACAACTTCAAGCTCAAGTTTGACCCAGAGCTCATCTTCAGTGAGCGTTTCCAGTACCAGAACCGTATTGCGGCCGAATTCAATACCCTGTATCACTGGCATCCACTGTTGCCGGACAACTTTCAGATCCAGGATCAGATCTACGGCTATCACCAGTTTGTGTTTAACAACTCTATCGTCACCACACATGGCATTCGCAACATGGTGGACTCCTTCACCAAACAGACTGCTGGACGGGTGTCTGGTGGACGTAACCTGCCACCTGCAGTTCAAGGAGTCGCTGTTAAAGTTCTGGAACAAACCAGACAGATGCGCTATCAATCTTTCAATGCATACAGAAGACGCTTCAACATGAAGCCCTACTCATCCTTTGAGGAGATGACAGGAGACAAAGATCTGGCTGCCCAGCTGAAGGAGCTGTACGGTCACGTAGACAAGGTTGAGCTGTATCCTGGCCTTCTTGTGGAGAAATCCAGACCCAACTCTGTGTTTGGGGAGACTATGGTGGAAATGGGAGCTCCCTACTCTCTCAAAGGCCTCATGGGAAATGCTATTTGTTCTCCTGAATACTGGAAGCCCAGCACATTTGGTGGGAAAGTGGGATTTGACATCGTTAACTCGGCTTCACTGAAGAAATTGGTGTGTTTGAACGTCAGTGGGCCCTGTCCGATGGTGTCCTTTCAGGTGCCAGATGTGAAATTTCAGAGTTCAGAAAACGTGAATTCAAGTTCAGTGCACTccacagtaaataatataaatccaACTGTTGTTTTGAACGAGCGGAGTTCAGAGCTGTAAAAGGTCTCAAAATCTTCAAAATCCCAGATACTTGATAtggttttgtaatttatttattttttatatatatttatttgaataatttattgcAGTAGTGtatttattgattgttttttttttttgtattgtgatcgATGTGCAACTTTGTTTCATAAATTCATGTGAGGTATTCAACTAATTGGACAAACACATTTCAAATGCCAATCAACTGttgcaaatgtttatttcataaataaaaacaaatgatattTTGCAAAAATA
>TCONS_00032145
GATACCCAGCTGAGATGCAAGGCACCCAACCCTCAATTGCTCCTTGGGCACTCAAAGCAAATAGCTGCCCATTGCTCATAGTGTGCGTTCAcaggatgtgtttgtgtgtgtgttctctcacTCTTTActcataatgtgtgtgtgcacttgtatTAGTCAATTTTAACTATGGGTAATGCCAAACATGACAATACTTACTTCACTTCATTAAACAtccatgttttttattttctcccAGGTGAGACCATCAAAATTGTGATCGAGGACTATGTTCAGCACTTGAGTGGATACAACTTCAAGCTCAAGTTTGACCCAGAGCTCATCTTCAGTGAGCGTTTCCAGTACCAGAACCGTATTGCGGCCGAATTCAATACCCTGTATCACTGGCATCCACTGTTGCCGGACAACTTTCAGATCCAGGATCAGATCTACGGCTATCACCAGTTTGTGTTTAACAACTCTATCGTCACCACACATGGCATTCGCAACATGGTGGACTCCTTCACCAAACAGACTGCTGGACGGGTGTCTGGTGGACGTAACCTGCCACCTGCAGTTCAAGGAGTCGCTGTTAAAGTTCTGGAACAAACCAGACAGATGCGCTATCAATCTTTCAATGCATACAGAAGACGCTTCAACATGAAGCCCTACTCATCCTTTGAGGAGATGACAG

Function

symbol description
ptgs2a Enables peroxidase activity. Acts upstream of or within animal organ development; cellular response to organic cyclic compound; and response to steroid hormone. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including cardiovascular system; digestive system; endoderm; gonad; and head. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; arthritis (multiple); cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).

GO:

id name namespace
GO:1990402 embryonic liver development biological_process
GO:0006954 inflammatory response biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0006979 response to oxidative stress biological_process
GO:0048545 response to steroid hormone biological_process
GO:0001516 prostaglandin biosynthetic process biological_process
GO:0008217 regulation of blood pressure biological_process
GO:0071407 cellular response to organic cyclic compound biological_process
GO:0019371 cyclooxygenase pathway biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004601 peroxidase activity molecular_function
GO:0004666 prostaglandin-endoperoxide synthase activity molecular_function
GO:0020037 heme binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020530-2 Enables peroxidase activity. Acts upstream of or within animal organ development; cellular response to organic cyclic compound; and response to steroid hormone. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including cardiovascular system; digestive system; endoderm; gonad; and head. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; arthritis (multiple); cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).

Ensembl:

ensembl_id ENSDARG00000004539

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032144 False 2135 mRNA 0.45 9 20916497 20923864
TCONS_00032145 True 673 lncRNA 0.45 2 20919171 20920335

Neighbor

gene id symbol gene type direction distance location
XLOC_016306 pdca coding downstream 26068 20882954 ~ 20890429 (-)
XLOC_016305 tpra coding downstream 49739 20811677 ~ 20866758 (-)
XLOC_016304 CABZ01020455.1 coding downstream 127799 20763289 ~ 20788698 (-)
XLOC_016303 FO681336.1 coding downstream 158798 20757582 ~ 20757699 (-)
XLOC_016301 dusp12 coding downstream 201403 20658259 ~ 20715094 (-)
XLOC_016308 lyrm4 coding upstream 56298 20980162 ~ 20981907 (-)
XLOC_016309 nrn1b coding upstream 68121 20991985 ~ 20994126 (-)
XLOC_016310 nebl coding upstream 152721 21076585 ~ 21082695 (-)
XLOC_016311 NA coding upstream 198324 21122188 ~ 21124115 (-)
XLOC_016312 bmi1b coding upstream 241066 21164930 ~ 21170517 (-)
XLOC_016302 AL954134.1 non-coding downstream 211974 20699481 ~ 20704523 (-)
XLOC_016298 NA non-coding downstream 453574 20453614 ~ 20462923 (-)
XLOC_016299 NA non-coding downstream 457488 20457947 ~ 20459009 (-)
XLOC_016295 NA non-coding downstream 768128 20124994 ~ 20148369 (-)
XLOC_016313 NA non-coding upstream 271664 21195528 ~ 21208559 (-)
XLOC_016314 CU464125.1 non-coding upstream 388878 21312742 ~ 21320684 (-)
XLOC_016316 NA non-coding upstream 457461 21381325 ~ 21383394 (-)
XLOC_016318 NA non-coding upstream 617742 21541606 ~ 21542043 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) G28148 NA non-coding CI01000004 null 5881481 ~ 6018658 (+)