XLOC_002239 (rad51c)


Basic Information

Item Value
gene id XLOC_002239
gene name rad51c
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 32662886 ~ 32672508 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004287
CACTATACACAAAAAAGTTATAACATGTCagcattatatttaataaatgtatagtaAAATATTGCTCCAACATTTGTAGAATAAATCATGTTTGTGGACTGTGGTTTGTGGTTTTATCCTGTAAAATATCACTGTCAGTAGGATAATTgttgaaagtaaataaaaaaaggctTTTCCATGTGCACAGTGGACTTTGCATAGATTCGTCACATTATTATTAGAACCAACTATTGAAACCAACAGTAGTCCTCGTACACTAAACTATAAATGGCGTCttactgagacttttattttgaagagcATTTTCCCCTAACAAGAGTCGTCGTGTCTTGTTTTGGAGGGATGATCAAAAAGAAGACATATATATATGGCGAAATATCAGTTTAAAGTGAATGAtttatgcttgtttttatttGACATAAATATTCCACGGTATAGCAATTCATTAAAGATTATATTGTACGCGTTTAAAAGTAAAAACTTGTATTTACGTTAACGTTACCTTGCTGACAGAAGCTTTGAAAGAATTCATCCAAAGGCGGCTAAAACTTTTAGTTTGGCTAAAACTGTCTGTCATCAGTACTAACCGACAGTCTGGGGTCTTAATCTGCATTTGAGgctgtttttttgtctttgtggACACTAGTTTTGGAAATGCACAGGACTGTACCGAGTCTCCCTCTGGCGCCGTCGGTGAAGGTGAAGCTCATCAATGCGGGTTTCCAAGCGGCTTCAGACCTGACAGACATGAGGCCTCTTCAGCTCTGCAAAGAGGCAGGTATTTCTCAAGAGGAGGCAGTGGAGCTGCTGCAGATGTTGAGAGATGATGCTCAGCCTCAACAGCAGAGGGCAGCAGCAGACGGCGTAACGGCACTGGATCTCCTGCACCAGGAGCAAACTCTGGGCAGCATAGTGACCTTCTGCTCTGGTCTAGATGATGCTATTGGCGGAGGCGTGCCTGTGGGAAAGACCACCGAGATCTGTGGGGCCCCTGGGGTCGGAAAGACTCAGCTTTGCATGCAGCTGGCTGTGGATGTGCAGATTCCTGTGTGTTTTGGAGGTCTGGGAGGAAAGGCGCTGTATATCGACACAGAAGGCAGTTTTTTGGTGCAGCGGGTTGCTGATATGGCAGAGGCAGCCGTTCAACACTGCACCCTCCTAGCAGAGGATACAGAACAGAAAGGAGCTCTGGAGGAACTTAATGTGGAGAAGATCCTCTCTAACCTCTTCTTGGTGCGTTGCCATGACTATGTAGAGCTGTTAGCGGAGGTTTACCTCCTACCTGACTTCCTGTCTGAGCATCCTGAGGTGCGGTTAGTAGTGATTGACAGCATCGCCTTCCCATTCCGGCATGACTTTGAGGATCTTTCTCAGAGGACCCGCCTCCTGAACGGCCTTGCCCAGCAGCTCATCCAACTAGCTACACAACACAGAGTGGCGGTtgttttgaccaatcagatgaccACACGAGTTTCAAATGGCCAGTCAAAACTGGTTCCTGCATTAGGGGAGAGTTGGGGTCACGCTGCGACGCAGAGGCTCATCCTGCACTGGGAGGGACAGAGAAGGCTCGCCTCCTTGTACAAGTCCCCAAGTCAAATGGAGGCCACAGTTCAATATCAGATTACAGTCCAGGGTTTCAGGGATTCCCCAGATGAACCCAGACCTACTTTTGATCCGTCTGAAGTCTCCTCTCCTTCAGCAAACCACAGCAAACGCCCTCGTTTGGAGGATCTGTCTTGA
>TCONS_00004288
gaagagcATTTTCCCCTAACAAGAGTCGTCGTGTCTTGTTTTGGAGGGATGATCAAAAAGAAGACATATATATATGGCGAAATATCAGTTTAAAGTGAATGAtttatgcttgtttttatttGACATAAATATTCCACGGTATAGCAATTCATTAAAGATTATATTGTACGCGTTTAAAAGTAAAAACTTGTATTTACGTTAACGTTACCTTGCTGACAGAAGCTTTGAAAGAATTCATCCAAAGGCGGCTAAAACTTTTAGTTTGGCTAAAACTGTCTGTCATCAGTACTAACCGACAGTCTGGGGTCTTAATCTGCATTTGAGgctgtttttttgtctttgtggACACTAGTTTTGGAAATGCACAGGACTGTACCGAGTCTCCCTCTGGCGCCGTCGGTGAAGGTGAAGCTCATCAATGCGGGTTTCCAAGCGGCTTCAGACCTGACAGACATGAGGCCTCTTCAGCTCTGCAAAGAGGCAGGTATTTCTCAAGAGGAGGCAGTGGAGCTGCTGCAGATGTTGAGAGATGATGCTCAGCCTCAACAGCAGAGGGCAGCAGCAGACGGCGTAACGGCACTGGATCTCCTGCACCAGGAGCAAACTCTGGGCAGCATAGTGACCTTCTGCTCTGGTCTAGATGATGCTATTGGCGGAGGCGTGCCTGTGGGAAAGACCACCGAGATCTGTGGGGCCCCTGGGGTCGGAAAGACTCAGCTTTGCATGCAGCTGGCTGTGGATGTGCAGATTCCTGTGTGTTTTGGAGGTCTGGGAGGAAAGGCGCTGTATATCGACACAGAAGGCAGTTTTTTGGTGCAGCGGGTTGCTGATATGGCAGAGGCAGCCGTTCAACACTGCACCCTCCTAGCAGAGGATACAGAACAGAAAGGAGCTCTGGAGGAACTTAATGTGGAGAAGATCCTCTCTAACCTCTTCTTGGTGCGTTGCCATGACTATGTAGAGCTGTTAGCGGAGGTTTACCTCCTACCTGACTTCCTGTCTGAGCATCCTGAGGTGCGGTTAGTAGTGATTGACAGCATCGCCTTCCCATTCCGGCATGACTTTGAGGATCTTTCTCAGAGGACCCGCCTCCTGAACGGCCTTGCCCAGCAGCTCATCCAACTAGCTACACAACACAGAGTGGCGGTtgttttgaccaatcagatgaccACACGAGTTTCAAATGGCCAGTCAAAACTGGTTCCTGCATTAGGGGAGAGTTGGGGTCACGCTGCGACGCAGAGGCTCATCCTGCACTGGGAGGGACAGAGAAGGCTCGCCTCCTTGTACAAGTCCCCAAGTCAAATGGAGGCCACAGTTCAATATCAGATTACAGTCCAGGGTTTCAGGGATTCCCCAGATGAACCCAGACCTACTTTTGATCCGTCTGAAGTCTCCTCTCCTTCAGCAAACCACAGCAAACGCCCTCGTTTGGAGGATCTGTCTTGAGGGTCTATAGCCGACCATTACTTCAAAGCTCTGGAAAGCCACTTCGACTTCAAAACTCGAAAtatgctaaagaaaaaaaaaggaaaaagaagagTATAAATGTACAGATATgaatatattatgtaaaatataattaagaACAGTTCGTTCCTGGTtttttaatagaataaaatacagtatattgattta

Function

symbol description
rad51c Predicted to enable ATP binding activity; ATPase, acting on DNA; and DNA binding activity. Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Predicted to be involved in meiotic DNA recombinase assembly and reciprocal meiotic recombination. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex and Rad51C-XRCC3 complex. Predicted to be active in replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group O and hereditary breast ovarian cancer syndrome. Orthologous to human RAD51C (RAD51 paralog C).

GO:

id name namespace
GO:0000707 meiotic DNA recombinase assembly biological_process
GO:0007131 reciprocal meiotic recombination biological_process
GO:0006281 DNA repair biological_process
GO:0048476 Holliday junction resolvase complex cellular_component
GO:0005657 replication fork cellular_component
GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex cellular_component
GO:0033065 Rad51C-XRCC3 complex cellular_component
GO:0005524 ATP binding molecular_function
GO:0000400 four-way junction DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0008821 crossover junction endodeoxyribonuclease activity molecular_function
GO:0008094 DNA-dependent ATPase activity molecular_function

KEGG:

id description
ko03440 Homologous recombination
ko03460 Fanconi anemia pathway
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-041010-204 Predicted to enable ATP binding activity; ATPase, acting on DNA; and DNA binding activity. Predicted to contribute to crossover junction endodeoxyribonuclease activity and four-way junction DNA binding activity. Predicted to be involved in meiotic DNA recombinase assembly and reciprocal meiotic recombination. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex and Rad51C-XRCC3 complex. Predicted to be active in replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group O and hereditary breast ovarian cancer syndrome. Orthologous to human RAD51C (RAD51 paralog C).

Ensembl:

ensembl_id ENSDARG00000068919

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004287 False 1743 mRNA 0.46 9 32662886 32672319
TCONS_00004288 True 1638 mRNA 0.47 9 32663180 32672508

Neighbor

gene id symbol gene type direction distance location
XLOC_002238 zbtb21 coding upstream 14083 32646402 ~ 32648803 (+)
XLOC_002236 map6a coding upstream 61506 32560667 ~ 32601380 (+)
XLOC_002237 NA coding upstream 70815 32584417 ~ 32592071 (+)
XLOC_002235 CR388187.1 coding upstream 266990 32395780 ~ 32395896 (+)
XLOC_002234 NA coding upstream 398588 32259743 ~ 32264298 (+)
XLOC_002240 ppm1e coding downstream 10581 32683089 ~ 32788832 (+)
XLOC_002241 CU929186.1 coding downstream 329811 33002319 ~ 33002433 (+)
XLOC_002242 myl10 coding downstream 498993 33171501 ~ 33179988 (+)
XLOC_002243 NA coding downstream 592873 33265381 ~ 33265687 (+)
XLOC_002244 NA coding downstream 684588 33357096 ~ 33359026 (+)
XLOC_002228 NA non-coding upstream 621040 31869282 ~ 32041846 (+)
XLOC_002245 NA non-coding downstream 687820 33360328 ~ 33368165 (+)
XLOC_002252 NA non-coding downstream 1197681 33870189 ~ 33871012 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000304_15785399_15786785 RAD51C coding CI01000304 null 15785399 ~ 15787028 (+)