XLOC_000241 (tyrp1b)


Basic Information

Item Value
gene id XLOC_000241
gene name tyrp1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 19332837 ~ 19346048 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000393
GGGGGGCACTACAGCACAGCAGAAACATACAGAGTGAGTGAAAGAGTGGGTCAGAAAACAGAGAGCGGATGATATAAGGATGTGGAAGAGTGTGTGTTTAGTGCTAATGTGCGTGGTGGTGACGCGAGCTCAGTTTCCGCGTCAGTGTATGACACCAGAAGGTCTGCGGAGCGGCACCTGCTGCCCATCACCTACAGGACTGGCCAATGATGAGTGCGGCTCCATCTCTGGCAGAGGTCAGTGTGTGTCAATTACTGCTGACAGGCGCCCACACGGCCCTCAGTATCCTCACGACGGCCGGGACGACAGAGAGAGATGGCCGCTTCGCTTCTTCAACAGAACCTGCCAATGCAACGGAAACTTCACTGGGTTCAACTGTGGCCGATGCCGACATGGTCTGACCGGGCCGAACTGTGATCAGAGAATCACCGTGGtgCGCCGTAACATCATGCAGATGTCTGCCGATGAGAAAAGAGCCTTTGTGAATGCTCTGGACCAGGCTAAAAGAACTGTTCATCCTGACCTGGTCATTTGCACCCGCCGCTTTCAGGAGATTTTGAGCCCTGATGGAGCAAGTGTTCAAGTTGAGAACATCACCATCTATAATTACTTCGTCTGGACCCATTACTATTCGGTCAGCAAGACTTACATGGGTCCAGGCCAGCAGAGCTTCGGGGGTGTTGATTTCTCTCATGAAGGCCCAGGATTTGTCACTTGGCATCGGTACCACCTTCTGCAACTGGAGAGAGACATGCAGgacatGCTTGGCGACCCGTCGTTTGCCCTGCCGTACTGGAACTTTGCTATTGGAGGCAGCGAGTGTGATATTTGCACCGATGACCTGATAGGAGCCAGAAGCAGCTTCGACACCAACGGCATCAGCTCCAACTCTGTGTTCTCTCAGTGGAGAGTCATCTGTGAGAGTGTGGAGGAGTATGAGACACTGGGCACCATCTGCAACAACACAGAATCCAGTCCAATCAGGAGAAACCCTGCTGGTAACGTGGCCCGTCCAATGGTTCAAAGATTACCAGAACCACAGGATGTCATCGACTGTCTAGAGCTCAACACCTTCGACACACCACCGTATTACTCCACGTCCTCTCAGAGCTTCAGGAACACTATTGAGGGTTACAGCGCTCCCCAGGGTAACTATGACCCAGTAGTGAGGAGTCTGCACAACCTGGCTCATTTGTTTCTCAATGGCACAGGTGGTCAGACTCACCTGTCACCAAACGACCCCATCTTCGTCCTGCTCCACACGTTCACTGATGCCATCTTTGATGAATGGCTTCAGAGGCACACCGCTGCAGGGACACTGGCTTATCCTGAGGAAAACGCTCCTATTGGGCACAACAGAGAGTTCAACATGGTTCCCTTCTGGCCACCTATCAGAAACGCTGAAATGTTTGTCAGTGCCCCCGACAACCTGGGATACACCTATGAGGTTCAGTGGCCAACTCGGGCATACACTATTTCTGAGATCATCACTATCGCTATAGTTGCAGTGGTGCTGGTTGTAGCGGTGGTGGGTGGAGTGATTGGGTGTGCAGTCCGGGCTCGCTCCTACCGCTCGGCTGAAGGCCTGGAGCCGCTGCTTGGGGAACAGTTCAGGCGCTACTCAGAGGATGAGCGCCACGCTTCACAGTCTGTGGTGTGACTAAGCCACTGATACACTTCTTCAACCGATTTATTATTGCACTGCACATCCACACTGAATGATCAATTACTAGCATTCAAAAGCAATGTAAAAGGTTTGTGAACACGGGGGGCTTCTTTTATGGCTGTTTATTGTCTTTCATGTCCAGCGAGACATTGAGAATACAGCCATGTGAGtgagcttttaaaatatatttaatgtgtCGTCATGAGGTTATGCACTGCTTATGAATGCCCTATGAACACATGACAAAGTTATTGTACAGTGTGAGATATTTTATATTACTCTgatataaaaagttttaaattc

Function

symbol description
tyrp1b Predicted to enable oxidoreductase activity. Acts upstream of or within several processes, including melanosome organization; response to thyroid hormone; and retinal pigment epithelium development. Predicted to be located in melanosome membrane. Predicted to be integral component of membrane. Predicted to be active in melanosome. Is expressed in several structures, including eye; hatching gland; immature eye; melanoblast; and pigment cell. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1).

GO:

id name namespace
GO:0097066 response to thyroid hormone biological_process
GO:0003406 retinal pigment epithelium development biological_process
GO:0032438 melanosome organization biological_process
GO:0043473 pigmentation biological_process
GO:0030318 melanocyte differentiation biological_process
GO:0042470 melanosome cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-249 Predicted to enable oxidoreductase activity. Acts upstream of or within several processes, including melanosome organization; response to thyroid hormone; and retinal pigment epithelium development. Predicted to be located in melanosome membrane. Predicted to be integral component of membrane. Predicted to be active in melanosome. Is expressed in several structures, including eye; hatching gland; immature eye; melanoblast; and pigment cell. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1).

Ensembl:

ensembl_id ENSDARG00000056151

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000393 True 1969 mRNA 0.50 8 19332837 19346048

Neighbor

gene id symbol gene type direction distance location
XLOC_000240 si:dkeyp-118a3.2 coding upstream 1305 19303241 ~ 19331532 (+)
XLOC_000239 NA coding upstream 67867 19253027 ~ 19264970 (+)
XLOC_000238 NA coding upstream 173552 19113197 ~ 19159285 (+)
XLOC_000237 ptpn9b coding upstream 219903 19094548 ~ 19112934 (+)
XLOC_000236 exosc9 coding upstream 240682 19083501 ~ 19092155 (+)
XLOC_000242 clockb coding downstream 86956 19433004 ~ 19466453 (+)
XLOC_000243 clrn2 coding downstream 169180 19515228 ~ 19517791 (+)
XLOC_000244 smc2 coding downstream 189072 19535120 ~ 19561801 (+)
XLOC_000245 fbxo10 coding downstream 256341 19602389 ~ 19632153 (+)
XLOC_000246 tmem192 coding downstream 303497 19649545 ~ 19665774 (+)
XLOC_000233 NA non-coding upstream 499394 18829172 ~ 18833443 (+)
XLOC_000230 NA non-coding upstream 968966 18355746 ~ 18363871 (+)
XLOC_000228 NA non-coding upstream 1163737 18165117 ~ 18169100 (+)
XLOC_000247 BX323590.2 non-coding downstream 359651 19705699 ~ 19705832 (+)
XLOC_000250 NA non-coding downstream 462393 19808441 ~ 19821195 (+)
XLOC_000253 NA non-coding downstream 677884 20023932 ~ 20027926 (+)
XLOC_000254 NA non-coding downstream 680841 20026889 ~ 20029066 (+)
XLOC_000256 NA non-coding downstream 800357 20146405 ~ 20147549 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000300_06858460_06868025 TYRP1B, TYRP1 coding CI01000300 null 6858423 ~ 6868644 (+)