XLOC_004126 (kiss1)



Basic Information


Item Value
gene id XLOC_004126
gene name kiss1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007122.7
NCBI id CM002895.2
chromosome length 45484837
location 23311452 ~ 23322182 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00007877
tctttttatatacattttattcttaCGCATGTGAACAGAATAGCACAGCAGTAAAGGTTAGAGGCTGATTTATGATGCTTTTGATAGCTTAAATTCTCTttgaagtgtgcatgtgtgtgggcCACGTGTGAGTTCATAAGTCTGAAAAACTGGATGAATACCACTGAATCTTGTGATCAAATAAGCAAAACTAAAAAGTGTTAATGATTCAAAAgacttttcatatttttaatcattttttattttcatttgttcttTTCTTTCAGAACTCTTCTCTTTCtgaaacacattaaaatgatgcTGCTTACTGTCATATTGATGTTGTCAGTGGCGAGGGTACACACAAACCCCTCTGGGCATTTTCAGTATTACTTAGAAGatgaaactccagaggaaacatCACTCCGGGTCCTCAGGGGAACAGACACTCGTCCCACAGATGGATCTCCTCCATCTAAACTCTCAGCGCTCTTCTCCATGGGTGCAGGTCCTCAGAAAAACACATGGTGGTGGTCTCCAGAAAGTCCTTACACCAAGAGGAGACAGAATGTAGCTTACTACAATCTCAACTCCTTCGGCCTCCGCTATGGCAAGAGAGAACAGGACATGCTCACACGATTGAAACAGAAAAGTCCTGTAAAGTGAAGGACCAATAATGTTCTTTGGTGTTTTATCATTTACGTAAAtacatgttttctgtttttatttctgttattttgttgggtgtaattagtttCATTTGGGTGTTTAGGTAGgggatatgtttttttttgtgtattatttttctgTTGGTCCTCTCTGAGGTATTTGCCTTCATGTTTTAGgtgttaaaaagaaagaaaaatacaagaaaaaagacaaataaacggACCTTACTCTAAGGGTTCGtaaaagtgtatttatttgtCCAGTGTTCTTTTATGTTACGTCCTTGATCCAAGACCAGGGCCGTAACAGTGATTATTAAATATGTGATGCCAGAAATAATATGGTTCTGATCTGTGGACGGACCATTAGTAGAATGTTGCTAGTCTAGCAGTTCATAAATTTCATTACAAAAGAGTTTTAGTTTCATTTCTCGGAGCTGATTGGTCAACAGCGTACTTATTCACCCATCACTCACTTTATATCATTATGGCACACTTTCAGCAAGAACCATGGGCCTATTTCAGTAGgattactgtttattatttaatcaagGAAGAATGCGTGACCCCTGCTGGTTTATTATTGCTTTATTCACCTTTAGTTTTGAGACCCCGCCCTTGACAAAACCTTTATTGGTGTGAAGGAAGCAATAAGTTTGGCGGGAATATTTACTTATTAACGCTTGACCCCACCTGAAGAACATCAAGACAAGATATGTACGAGGTCAGCCATTTAAACGATGAGAAATAgttaaaataacatataatataaatatgcagtaCATCTGGCCACCCCTATAATGCTCCGTACAACTGTGCATGTATGATCGTCATCGGCAGACGATGTGGGAAAATGTTCAGTCAGATCAAGAGCACCGATAGAAACCGTGTTCACACAAGACACTTTTTATGTAAAATAGATGTTATATCCTGTCACTATTTGTTTCATAAATAGGTTGTGTTTGAGAATCACAC
>TCONS_00007878
ACAAGCTCCATACCTGCAAGTGTAAAGAACTCTTCTCTTTCtgaaacacattaaaatgatgcTGCTTACTGTCATATTGATGTTGTCAGTGGCGAGGGTACACACAAACCCCTCTGGGCATTTTCAGTATTACTTAGAAGatgaaactccagaggaaacatCACTCCGGGTCCTCAGGGGAACAGACACTCGTCCCACAGATGGATCTCCTCCATCTAAACTCTCAGCGCTCTTCTCCATGGGTGCAGGTCCTCAGAAAAACACATGGTGGTGGTCTCCAGAAAGTCCTTACACCAAGAGGAGACAGAATGTAGCTTACTACAATCTCAACTCCTTCGGCCTCCGCTATGGCAAGAGAGAACAGGACATGCTCACACGATTGAAACAGAAAAGTCCTGTAAAGTGAAGGACCAATAATGTTCTTTGGTGTTTTATCATTTACGTAAAtacatgttttctgtttttatttctgttattttgttgggtgtaattagtttCATTTGGGTGTTTAGGTAGgggatatgtttttttttgtgtattatttttctgTTGGTCCTCTCTGAGGTATTTGCCTTCATGTTTTAGgtgttaaaaagaaagaaaaatacaagaaaaaagacaaataaacggACCTTACTCTAAGGGTTCGtaaaagtgta

Function


symbol description
kiss1 Enables G protein-coupled receptor binding activity. Acts upstream of or within neuronal action potential and regulation of fear response. Predicted to be active in neuron projection. Is expressed in several structures, including brain; fat cell; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0019228 neuronal action potential biological_process
GO:0007204 positive regulation of cytosolic calcium ion concentration biological_process
GO:1903365 regulation of fear response biological_process
GO:0043005 neuron projection cellular_component
GO:0031773 kisspeptin receptor binding molecular_function
GO:0001664 G protein-coupled receptor binding molecular_function

KEGG:

id description
ko04080 Neuroactive ligand-receptor interaction
ko04929 GnRH secretion

ZFIN:

id description
ZDB-GENE-080128-1 Enables G protein-coupled receptor binding activity. Acts upstream of or within neuronal action potential and regulation of fear response. Predicted to be active in neuron projection. Is expressed in several structures, including brain; fat cell; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).

Ensembl:

ensembl_id ENSDARG00000075829

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00007877 False 1622 mRNA 0.37 2 23311452 23314242
TCONS_00007878 True 659 mRNA 0.40 3 23312176 23322182

Neighbor


gene id symbol gene type direction distance location
XLOC_004125 BX571675.2 coding downstream 2134 23305755 ~ 23309318 (-)
XLOC_004124 optc coding downstream 92085 23205889 ~ 23219367 (-)
XLOC_004123 CR555297.1 coding downstream 152145 23159189 ~ 23159307 (-)
XLOC_004122 atp2b4 coding downstream 230482 22920587 ~ 23080970 (-)
XLOC_004121 mdm4 coding downstream 394811 22890997 ~ 22916641 (-)
XLOC_004127 golt1a coding upstream 5602 23327784 ~ 23332592 (-)
XLOC_004128 plekha6 coding upstream 20814 23342996 ~ 23525611 (-)
XLOC_004129 pik3c2b coding upstream 271655 23593837 ~ 23697217 (-)
XLOC_004130 LO016980.1 coding upstream 333168 23655350 ~ 23655478 (-)
XLOC_004131 CR354444.1 coding upstream 577818 23900000 ~ 23901361 (-)
XLOC_004063 CR854846.1 misc downstream 7183774 16127382 ~ 16127678 (-)
XLOC_004019 CR450764.8 misc downstream 10619761 12691395 ~ 12691691 (-)
XLOC_004015 CR450764.4 misc downstream 10689685 12621518 ~ 12621767 (-)
XLOC_004013 CABZ01022569.1 misc downstream 10720156 12590999 ~ 12591296 (-)
XLOC_004008 BX000700.19 misc downstream 10798190 12512966 ~ 12513262 (-)
XLOC_004117 NA non-coding downstream 1217055 22089435 ~ 22094397 (-)
XLOC_004116 NA non-coding downstream 1405392 21893602 ~ 21906060 (-)
XLOC_004115 CT573222.1 non-coding downstream 1558863 21752475 ~ 21752589 (-)
XLOC_004140 NA non-coding upstream 1387602 24709784 ~ 24714293 (-)
XLOC_004141 CR628365.1 non-coding upstream 1497083 24819265 ~ 24820001 (-)
XLOC_004142 CR628365.2 non-coding upstream 1645589 24967771 ~ 24967887 (-)

Expression



Co-expression Network