ada (ada)


Basic Information

Item Value
gene id ada
gene name ada
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035911.1
NCBI id CM008314.1
chromosome length 35718434
location 10969289 ~ 10989500 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022677175.1
GCGCGCAGATAAGTGGCTGTGTAATGTTAAGGCGCGCGGGCGGCTCGAGCTCAGGACTCGCTGCTGAGAGCCGGAAGGAGTCGGACCCGCGTGCTGCCGAGTTTCTGCGCTGTGCTGACCGAGATTACCCGGGATTAGAGCGACCATGGCCGGGGTGTGTGTGAACGATAAGACGCCCGGGCAGGACTGCGAGAGGAAGGACAAGGTTGAGCTACATGTGCATCTAGATGGCGCAATCCGGATTGAGACCATTATGGATGTGGCTAAGAGGCGAGGTATTCCTCTTTCTGCAGACACGGTGGAAGAGTTGACCCGCCAGATCACAGTCACTGAACCCTCATCGCTTACCGAGTTCCTGGGCAAGTTCAGTAAATTCATGCACGTCATTGCAGGGGACAGAGAAGCCATTAAGAGAATAGCGTACGAGTTTGTGGAGACCAAATCCAAAGAGGGAGTGATCTACGTGGAGGCGAGGTACAGCCCTCACTTTATGGCAAACTGTGACGTGGATCCGATACCGTGGGATCAGGAAAAAGGGGATCTGACACCAGACGAAGTGGTAAATCTGGTGAATCAGGGCCTGAAGGAGGGCGAGGAGGCCTTCAAGACCAAAGCCAGGTCCATTCTGTGCTGCATGCGCCACATGCCAAACTGGTCCATGGACGTGGTGGAGCTCTGTAAGAAGTACCGGAATGATGGAGTGGTGGCTATAGATTTAGCAGGAGACGAGTCTCTAAACTGCGAAATGTATCCAGGACACTTAAACGCGTATACGGAAGCAGTAAAAAGCGGGATCCACAGAACAGTCCATGCAGGAGAGGTGGGCGCAGCGTCTGTGGTTAAagagGCTGTCGAGATCCTGAAGGCCGAGCGCATTGGACACGGCTACCACACCATAGACGACAAGGAACTGTACCAACAGCTGCTTAAAGACAGGATGCACTTCGAGatgtGTCCAGTCTCCAGCAGACTGACAGGAGCTTGTGACCCAGACTTCACGAAGCATCCGCTCATCAGGTTTAAGGAGGACAAGGCCAACTTTTCTCTGAACACAGACGACCCAACAGTCTTCAACTCCACCCTCGAATCTGACTACCAGGCTGTGAAGAAATATATGGGCTTCACTGAAGAAGACTTCAGAGATCTGAATATAAACGCGGCAAAGTCCTGCTTCCTGCCTGATAACGAGAAGGAGGAGCTCCTGAATCATCTCTACAAAGTTTACGGCATGGTGAACGACACCAGCTTCTAAACGGatctccttcactcctccactcctccactcatCCGCTCTTACCTCCAATTACTCTACCAATCTCAGACATTGGGGAAGGCTTTTATAGTTTACCGTACAGTTTTCAAGTACTTATTGTTGTTTTCTATTTGGTTGAAAGATTTAAGAGTCATGGaatgaaaa

Function

symbol description
ada Enables adenosine deaminase activity. Predicted to be involved in T cell activation; negative regulation of adenosine receptor signaling pathway; and nucleobase-containing small molecule metabolic process. Predicted to act upstream of or within nucleotide metabolic process and purine ribonucleoside monophosphate biosynthetic process. Predicted to be located in several cellular components, including cell junction; cytoplasmic vesicle lumen; and lysosome. Predicted to be active in cytosol and external side of plasma membrane. Is expressed in several structures, including digestive system; gill; heart; kidney; and muscle. Human ortholog(s) of this gene implicated in adenosine deaminase deficiency; asthma; and severe combined immunodeficiency. Orthologous to human ADA (adenosine deaminase).

NR:

description
PREDICTED: adenosine deaminase isoform X1

GO:

id name namespace
GO:0042110 T cell activation biological_process
GO:0060169 negative regulation of adenosine receptor signaling pathway biological_process
GO:0046103 inosine biosynthetic process biological_process
GO:0006154 adenosine catabolic process biological_process
GO:0043103 hypoxanthine salvage biological_process
GO:0009117 nucleotide metabolic process biological_process
GO:0009168 purine ribonucleoside monophosphate biosynthetic process biological_process
GO:0005829 cytosol cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0060205 cytoplasmic vesicle lumen cellular_component
GO:0030054 cell junction cellular_component
GO:0004000 adenosine deaminase activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K01488 add, ADA; adenosine deaminase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022677175.1 True 1417 mRNA 0.51 11 10969289 10989500

Neighbor

gene id symbol gene type direction distance location
LOC103044697 gdi1,LOC108276388,LOC108425579,LOC107564645 coding upstream 82203 10874498 ~ 10887086 (+)
LOC103041826 NA coding upstream 110492 10839043 ~ 10858797 (+)
LOC103021375 LOC108441398,LOC107570136,LOC107668555,LOC107716162,LOC107564641,LOC107695834,LOC107737499 coding upstream 208223 10749637 ~ 10761066 (+)
magi3 magi3 coding upstream 226585 10535483 ~ 10742704 (+)
tmem269 pss,LOC108275772,LOC100689985,LOC107570193,LOC108441403,LOC107668567,LOC107695831,LOC107568457,LOC101473555,LOC102292634 coding upstream 448477 10507956 ~ 10520812 (+)
fitm2 NA coding downstream 120870 11110370 ~ 11113964 (+)
LOC103046525 LOC108425571 coding downstream 126029 11115529 ~ 11127920 (+)
LOC103032800 lrp1,LOC108425568,LOC107593902,LOC107673053 coding downstream 196248 11185748 ~ 11363351 (+)
LOC103033368 LOC108425561,LOC108276129,LOC107593912,LOC107673097,LOC107737522,LOC107591068,LOC107716150 coding downstream 662009 11651509 ~ 11665934 (+)
LOC103033689 avpr2,LOC106567019 coding downstream 718853 11708353 ~ 11742030 (+)
G131073 NA non-coding upstream 36363 10930721 ~ 10932926 (+)
G131072 NA non-coding upstream 38600 10930421 ~ 10930689 (+)
G131046 NA non-coding upstream 135263 10833571 ~ 10834026 (+)
G131016 NA non-coding upstream 203101 10764217 ~ 10766188 (+)
G131030 NA non-coding upstream 301275 10666409 ~ 10668014 (+)
G131085 NA non-coding downstream 2403 10991903 ~ 10994146 (+)
G131088 NA non-coding downstream 6174 10995674 ~ 11027976 (+)
G131094 NA non-coding downstream 51423 11040923 ~ 11046860 (+)
G131099 NA non-coding downstream 72353 11061853 ~ 11069210 (+)
G131086 NA non-coding downstream 84989 11074489 ~ 11075514 (+)
LOC107197146 NA other upstream 139731 10815860 ~ 10829558 (+)
LOC103038829 NA other upstream 1041056 9922981 ~ 9928233 (+)
mlh3 mlh3,LOC107591079 other upstream 1048294 9911307 ~ 9920995 (+)
LOC111194075 tuba1b,LOC107697946,LOC103148207,LOC105941124,LOC107707017,LOC107715008,LOC107557552 other upstream 1097517 9856406 ~ 9871772 (+)
G130844 NA other upstream 1211938 9756952 ~ 9757351 (+)
G131313 LOC107737517,LOC107716155,LOC107593906,LOC107668344,LOC107591063 other downstream 502063 11491563 ~ 11502723 (+)
LOC111194085 LOC108425553 other downstream 932840 11922340 ~ 11978761 (+)
LOC103031050 NA other downstream 1251196 12240696 ~ 12334090 (+)
sall4 sall4 other downstream 1699654 12689154 ~ 12763710 (+)
G131677 NA other downstream 1923991 12913491 ~ 12940847 (+)

Expression


Co-expression Network