XLOC_005713 (lhb)


Basic Information

Item Value
gene id XLOC_005713
gene name lhb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 2523032 ~ 2526033 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011331
TGGTTAGCACCGAGTTTCGGTGTCTTATATAAATCTGGACACGCAGAGACACTTACAACAGCCTGCTGAGCAACCGCAACGCCTGTCAAGATGTTATTGGCTGGAAATGGTGTCTTCTTTCTCTTCTCTTTGTTTTTCCTGCTGGCGGCTGCTCAGAGCTTGGTTTTTCCACGCTGTGAGCTAGTAAATGAGACGGTATCGGTGGAAAAAGAGGGCTGTCCAAAATGCCTGGTGTTTCAGACCACCATCTGCAGCGGCCACTGCGTAACAAGGGATCCCGTTTACAAGAGCCCGTTTTCCACCGTCCACCAGACAGTGTGCACGTACCGGGACGTCCGCTATGAGACCATTAACCTGCCCGACTGTTCCGCCGGTGTGGACCCGCAGATCACATACCCGGTGGCGCTGAGCTGCGACTGCAGTCTGTGCACCATAAACACTTCCGACTGCACCATCCAGAGCCTGCAGCCCGACTTCTGCATGTCCCAGAGAGAGGATTTCCCCGCATACTAGACCTCGGACAACTCACATCAACCTACACACACAGTCGAGCTCAGCATTATTAGACCTCCTGTATGTTTTttccattaatatatatattttcaagacactagtattcagcttaaagtgacatttaaagactaaactaggttaattagggggGAAAGTAGAGTCATTGtataatagtggtttgttctggagacaatccaaaactaatattgcttaagggggctaataaaattgaccttaaaatgaatttaaataatttaaaaactgcatttattctagtcgaaataaaagaaataagactttctccagaagaaaaaatattataggaaatactgcaaaaaattcctgaatctgtttaacatcattcgggaaatcaaaggagggctaataactgtgacttcagctgtacatcaATAAAGAGGCTGGTTCTTAAATTCATTTATATGCTCAAGAGGATTTTATTGTGTGCATTTTAATGGCACAGTTTGGCCAGAAATTAAATGTTTGCCATCATTTAATCACCTTTTACTTGCTTCaagcctgtttgactttcttctgttgaacacaaagtttcagatttcttcaaaatatcttcattaggTTCAACCGAAGAAAGAAACCAATTAgagtagattttcatttttaggtgaactatcccattaaagaGCTGCTACACTGTGAAATTTGCAATGTTTTAACCTAAATTAGTGGCACAAAATGGACAAATCCAACAGCTGTGTTGAAAATTTCATTTATACTAGCCCAAATACAAAAGATTACCTTGTGTTTGTCAGGTTGAAACAACCCAGAATTTTCTAAAGCGAACTTGATGGTGAGTTATTGTTGGAAataaacctctctaaaacca

Function

symbol description
lhb Enables hormone activity. Acts upstream of or within female gonad development; gamete generation; and sex determination. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including endocrine system; female organism; kidney; liver; and male organism. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 23 with or without anosmia. Orthologous to several human genes including LHB (luteinizing hormone subunit beta).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0030728 ovulation biological_process
GO:0007530 sex determination biological_process
GO:0007283 spermatogenesis biological_process
GO:0001556 oocyte maturation biological_process
GO:0008585 female gonad development biological_process
GO:0009755 hormone-mediated signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005179 hormone activity molecular_function

KEGG:

id description
ko04024 cAMP signaling pathway
ko04080 Neuroactive ligand-receptor interaction
ko04929 GnRH secretion
ko04912 GnRH signaling pathway
ko04913 Ovarian steroidogenesis
ko04917 Prolactin signaling pathway

ZFIN:

id description
ZDB-GENE-040806-2 Enables hormone activity. Acts upstream of or within female gonad development; gamete generation; and sex determination. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including endocrine system; female organism; kidney; liver; and male organism. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 23 with or without anosmia. Orthologous to several human genes including LHB (luteinizing hormone subunit beta).

Ensembl:

ensembl_id ENSDARG00000099363

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011331 True 1378 mRNA 0.41 3 2523032 2526033

Neighbor

gene id symbol gene type direction distance location
XLOC_005712 arfgef3 coding upstream 24711 2442841 ~ 2498321 (+)
XLOC_005711 elovl5 coding upstream 105623 2394264 ~ 2417409 (+)
XLOC_005709 gclc coding upstream 130368 2357637 ~ 2392664 (+)
XLOC_005710 CR376766.1 coding upstream 136499 2386413 ~ 2386533 (+)
XLOC_005708 CR376766.2 coding upstream 170037 2352289 ~ 2352995 (+)
XLOC_005714 plpp4 coding downstream 12603 2538636 ~ 2665113 (+)
XLOC_005715 NA coding downstream 145399 2671432 ~ 2676336 (+)
XLOC_005716 wdr11 coding downstream 206918 2732951 ~ 2828218 (+)
XLOC_005717 si:ch211-233m11.1 coding downstream 304541 2830574 ~ 2849857 (+)
XLOC_005718 BX571701.4 coding downstream 307059 2833092 ~ 2833207 (+)
XLOC_005706 NA non-coding upstream 370016 2149770 ~ 2153016 (+)
XLOC_005705 NA non-coding upstream 489989 1983311 ~ 2033043 (+)
XLOC_005701 CABZ01044297.1 non-coding upstream 757410 1765507 ~ 1765622 (+)
XLOC_005722 NA non-coding downstream 397887 2923920 ~ 2928455 (+)
XLOC_005723 NA non-coding downstream 417248 2943281 ~ 2944990 (+)
XLOC_005725 AL935294.2 non-coding downstream 733510 3259543 ~ 3260961 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000005_04731666_04732248 LHB coding CI01000005 null 4731588 ~ 4732248 (-)