XLOC_001236 (fbxw7)


Basic Information

Item Value
gene id XLOC_001236
gene name fbxw7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 24870661 ~ 25144439 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001998
GACGGTCAATGAGACAGACGGGCGGGTCGTTGGAATCTTCCTTTTCGGCTTCAAATGCATCCGTCCGTGGATGAGTATGTCCCTGTCGGATCTATCCGGGATTAATATAGCCCTTATCGAGCAGATATATTACCATAAATTCTTCATCGACTCTCAGTGAATCGCAGCCGGGATTACCGTCATCACCATCACCATGGGTTTCTACGGCACTTTAAAGATGATCTTCTATAAAATGAAGAGAAAGTTGGACCATGGCCCAGAGGTTCGATCTTTCACTACAGGAAAAAAGCCCTGTCCAAGTCCCACAGGACAGCAATACCCAGCAACATTTGGAGACCTGCGAGCGGTCAATGGGCAGGTTCCACAGAGACGACGGATTACATCCATCCAGCCCCCCACAGGCCTCCAAGAATGGCTTCGCACCTTTCAGAGCTGGAGTGGCCCAGAGAAGCTGCTTGCACTGGATGAGTTAATCGACAGCTGTGAGCCCACACAGGTCAAACATATGATGCAGGTGATCGAACCGCAGTTTCAGAGAGACTTCATCTCACTGCTACCGAGAGAGTTGGCTTTGCACGTGTTGTCATTTCTGGAGCCAAAGGATCTGCTTCAGGCAGCCCAGACGTGTCGTTACTGGCGTATTCTAGCAGAGGACAACCTGCTCTGGAAGGAAAAATGCAAAGAAGAAgGTATTGATGAGCCCTTGCACATAAAGAGAAGGAAGGTCATCAAGCCGGGGTTCACACACAGTCCTTGGAAGAGTGCCTACATCAGACAACACAGAATAGACACCAACTGGAGGAGAGGAGACCTCAAGTCACCTAAGGTGTTGAAAGGCCATGACGACCATGTCATCACCTGCCTCCAGTTCTGTGGAAACCGCATAGTGAGCGGCTCAGACGACAACACGCTCAAAGTGTGGTCTGCTGTTACTGGGAAGTGTTTGCGCACGTTAGTGGGCCACACCGGTGGGGTTTGGTCCTCTCAGATGCGAGACAACATCATTATCAGTGGATCCACGGACCGAACGCTCAAGGTCTGGAATGCAGAGACGGGAGAATGTATCCACACGCTGTACGGTCATACCTCAACAGTACGCTGTATGCACTTGCATGAGAAAAGGGTGGTGAGTGGTTCTCGGGACGCCACGCTCCGGGTTTGGGACATCGAGACGGGTCAGTGTTTGCACGTGCTCATGGGTCACGTGGCAGCCGTTCGCTGCGTACAGTACGACGGCCGCCGGGTGGTCAGCGGAGCCTACGACTTTATGGTCAAAGTGTGGGATCCTGAAACTGAGACCTGCCTACACACACTCCAGGGTCACACCAACAGAGTCTACTCTCTACAGTTCGATGGCATCCACGTGGTGAGCGGTTCGTTGGACACATCAATTCGGGTGTGGGATGTAGAGACGGGGAACTGTATTCACACACTCACAGGTCATCAGTCCCTCACCAGCGGCATGGAGCTTAAAGATAATATCCTAGTATCTGGAAACGCAGACTCCACCGTCAAGATCTGGGACATCAAGACCGGCCAGTGCCTACAGACACTGCAAGGTCCTCACAAGCACCAGAGTGCAGTAACATGCCTGCAGTTCAACAAGAATTTTGTCATCACCAGTTCGGATGACGGTACGGTGAAGTTGTGGGACCTTCGAACGGGCGAGTTCATCCGCAACCTGGTCACACTGGAGAGCGGAGGCAGCGGCGGTGTGGTCTGGCGCATCCGTGCCTCTAATACCAAACTGGTTTGTGCAGTGGGCAGCCGGAACGGCACGGAGGAAACCAAGCTCCTGGTGCTGGACTTTGACGTGGACATGAAGTGAAGGGGCGAATTTATAGGGGACTTGTTTGGAAAATGGGGAGGGAGGGGAAAGAGCAACCTGTCCCGGGTCATTCTGCGCCAGGACTGACCGCTCACTTCATGGCATCTCCACCTCCCCGATAAGTTGCCGCCAACATCTCTCCCCCCCCGCTGTGCCACGGTTCATGACTGCCACCACAGTTCCGTTCACCTACCGAGGGGGTGGGGGCAGACGCTCATGCACCACAGCATTCTGGGAAGGAAACTGACAAGAAGGACATGGGAAGACAGGATTGTCCCTTTTCCTACCACTCAAGGCGACCTTGCACAGAGACTTGTTTGCTCAAGCCTGACTGAAATTCGCACCCATAATgtacaaatgttatttttttgatCAAAGCAGTCGACACTGTATACATGAGACCCTAACGCATCAACACGGAGCGATAC
>TCONS_00001999
TCTTATTTAAGCGACGCGAGCAAGGGTGACGTTATTGGACGACACCGTGACGCTATCATCCGTGGACAGGGAGTCGTACAGGAATCGGTTGGATAAAGGCGATCGCGCTTTAACGGAGCAGCATCGGAGTCGCGTGCCGCATCCCTTGCTTTCTCAGATCGGTCACATATTATTCTATGGGGGATCTGAGTTTTTGCAGAAGATAACGAAGAAATTTCAGCTCTCCCTGATGCAGGGCTCCGAAGGGTGCGAATGACGCTCAGACTTTATTTCGGCGGATGAAAATGTTTGGTTTGTGCTTGTAAAACTTCAGCTCGTTTTCAGAGGATCGTTTCATCTTGCGTTCGGGCAAGCCGGAGAGGAGAAGAGGGGAGACCGGTTTATCCTAACCGAATTCTGGATTGGATATCTGAGGAAACTAACCGTTCGTTTGCACATAGGAGCTTTCCCCCTTCGCCTTTCCACCAGTTTCCAGGAGGTCAGAGGTGGAGGATCACACTTGAAGGACTCTCAGCTGCCAGACAAGTGAATCaATGCCAAGTCCTTGTCCTCCTCAGACAGCCTAGCGAAGGTGCAGGAGGTAGCAAGCTGGCTTTTGGAAATGAACCAGGATCTGCTGTCGGGGGGCAGCGGCAGCAGGGCGGCCCAGCAGCAGAGACCGAGACCCGGAACGGCGGGGGCAGGTAACAGCATCTCAGGCCGCACACCTCAGCCccagccggagcacccggaccaGGTGCTGGAGGAGCCGGAGCAAGAGGAGGCGCAGCAGCAGAGGAGAGAACCAGCTGAGGAGGAAGATGAGGGAGGACCAGAGCGGCAGCAGGACGGTGACGAGCAGCCATGGCCTTCCGGAGGCGAACCGATGGAGGATGGAGAAGGGCGGAGGAGCGAGGTGAATGGAGACGAAAAAGGCGCCCAGTGGCTTTGGGAGCAGGAACAGCGCAGGAGGAGAAGACCGCATCGTGAGGAAGAAGAGGAgaacgaggaggaggaggagaataaTAACAGTGGGAGGGAAGGACAGGTCGGGGCAGGACTCCGTTCGGAGGAAGACGACGACCGGCCGGAGGAGGACAATGAGGGCGAGGAGGAAATGGACCAGGACAGCGATGAGTTTGAACATTCGGAGGAGAGCGAgagggaagaggaggaggaggatggtgAAGAGGAGGAAGGCGAGGAAGGCCTCCATTCGCCCTCACTTAGGACCAGTGTGTCTGACCATAATGATAACACGGACCAGTCTTCTGGACGACAGCGCCAAAGCCTTCGCTCACCGAATAGGATGAAGAGAAAGTTGGACCATGGCCCAGAGGTTCGATCTTTCACTACAGGAAAAAAGCCCTGTCCAAGTCCCACAGGACAGCAATACCCAGCAACATTTGGAGACCTGCGAGCGGTCAATGGGCAGGTTCCACAGAGACGACGGATTACATCCATCCAGCCCCCCACAGGCCTCCAAGAATGGCTTCGCACCTTTCAGAGCTGGAGTGGCCCAGAGAAGCTGCTTGCACTGGATGAGTTAATCGACAGCTGTGAGCCCACACAGGTCAAACATATGATGCAGGTGATCGAACCGCAGTTTCAGAGAGACTTCATCTCACTGCTACCGAGAGAGTTGGCTTTGCACGTGTTGTCATTTCTGGAGCCAAAGGATCTGCTTCAGGCAGCCCAGACGTGTCGTTACTGGCGTATTCTAGCAGAGGACAACCTGCTCTGGAAGGAAAAATGCAAAGAAGAAgGTATTGATGAGCCCTTGCACATAAAGAGAAGGAAGGTCATCAAGCCGGGGTTCACACACAGTCCTTGGAAGAGTGCCTACATCAGACAACACAGAATAGACACCAACTGGAGGAGAGGAGACCTCAAGTCACCTAAGGTGTTGAAAGGCCATGACGACCATGTCATCACCTGCCTCCAGTTCTGTGGAAACCGCATAGTGAGCGGCTCAGACGACAACACGCTCAAAGTGTGGTCTGCTGTTACTGGGAAGTGTTTGCGCACGTTAGTGGGCCACACCGGTGGGGTTTGGTCCTCTCAGATGCGAGACAACATCATTATCAGTGGATCCACGGACCGAACGCTCAAGGTCTGGAATGCAGAGACGGGAGAATGTATCCACACGCTGTACGGTCATACCTCAACAGTACGCTGTATGCACTTGCATGAGAAAAGGGTGGTGAGTGGTTCTCGGGACGCCACGCTCCGGGTTTGGGACATCGAGACGGGTCAGTGTTTGCACGTGCTCATGGGTCACGTGGCAGCCGTTCGCTGCGTACAGTACGACGGCCGCCGGGTGGTCAGCGGAGCCTACGACTTTATGGTCAAAGTGTGGGATCCTGAAACTGAGACCTGCCTACACACACTCCAGGGTCACACCAACAGAGTCTACTCTCTACAGTTCGATGGCATCCACGTGGTGAGCGGTTCGTTGGACACATCAATTCGGGTGTGGGATGTAGAGACGGGGAACTGTATTCACACACTCACAGGTCATCAGTCCCTCACCAGCGGCATGGAGCTTAAAGATAATATCCTAGTATCTGGAAACGCAGACTCCACCGTCAAGATCTGGGACATCAAGACCGGCCAGTGCCTACAGACACTGCAAGGTCCTCACAAGCACCAGAGTGCAGTAACATGCCTGCAGTTCAACAAGAATTTTGTCATCACCAGTTCGGATGACGGTACGGTGAAGTTGTGGGACCTTCGAACGGGCGAGTTCATCCGCAACCTGGTCACACTGGAGAGCGGAGGCAGCGGCGGTGTGGTCTGGCGCATCCGTGCCTCTAATACCAAACTGGTTTGTGCAGTGGGCAGCCGGAACGGCACGGAGGAAACCAAGCTCCTGGTGCTGGACTTTGACGTGGACATGAAGTGAAGGGGCGAATTTATAGGGGACTTGTTTGGAAAATGGGGAGGGAGGGGAAAGAGCAACCTGTCCCGGGTCATTCTGCGCCAGGACTGACCGCTCACTTCATGGCATCTCCACCTCCCCGATAAGTTGCCGCCAACATCTCTCCCCCCCCGCTGTGCCACGGTTCATGACTGCCACCACAGTTCCGTTCACCTACCGAGGGGGTGGGGGCAGACGCTCATGCACCACAGCATTCTGGGAAGGAAACTGACAAGAAGGACATGGGAAGACAGGATTGTCCCTTTTCCTACCACTCAAGGCGACCTTGCACAGAGACTTGTTTGCTCAAGCCTGACTGAAATTCGCACCCATAATgtacaaatgttatttttttgatCAAAGCAGTCGACACTGTATACATGAGACCCTAACGCATCAACACGGAGCGATAC
>TCONS_00002951
GAGGCGCAGCAGCAGAGGAGAGAACCAGCTGAGGAGGAAGATGAGGGAGGACCAGAGCGGCAGCAGGACGGTGACGAGCAGCCATGGCCTTCCGGAGGCGAACCGATGGAGGATGGAGAAGGGCGGAGGAGCGAGGTGAATGGAGACGAAAAAGGCGCCCAGTGGCTTTGGGAGCAGGAACAGCGCAGGAGGAGAAGACCGCATCGTGAGGAAGAAGAGGAgaacgaggaggaggaggagaataaTAACAGTGGGAGGGAAGGACAGGTCGGGGCAGGACTCCGTTCGGAGGAAGACGACGACCGGCCGGAGGAGGACAATGAGGGCGAGGAGGAAATGGACCAGGACAGCGATGAGTTTGAACATTCGGAGGAGAGCGAgagggaagaggaggaggaggatggtgAAGAGGAGGAAGGCGAGGAAGGCCTCCATTCGCCCTCACTTAGGACCAGTGTGTCTGACCATAATGATAACACGGACCAGTCTTCTGGACGACAGCGCCAAAGCCTTCGCTCACCGAATAGGGTAAGGAGACTATCATTTTTATAATGCATTGCATTATAAAAAGCATTCATCTTAAGCCATATGTCATAGATGTGCTGTTATTAAAGCTTTTGCACTGTGAGTTAGTGAACAGCAGGTGGCAGTGTGGTCTAGCAGCTGTTTTTAAGCAATGCAGCTCACTTTTCTAACCTCTCGAAATGCTCCTGCAAAGCTCATTCTAGTCGTGCTGTTCAttg
>TCONS_00002952
ATCCGTGGACAGGGAGTCGTACAGGAATCGGTTGGATAAAGGCGATCGCGCTTTAACGGAGCAGCATCGGAGTCGCGTGCCGCATCCCTTGCTTTCTCAGATCGGTCACATATTATTCTATGGGGGATCTGAGTTTTTGCAGAAGATAACGAAGAAATTTCAGCTCTCCCTGATGCAGGGCTCCGAAGGGTGCGAATGACGCTCAGACTTTATTTCGGCGGATGAAAATGTTTGGTTTGTGCTTGTAAAACTTCAGCTCGTTTTCAGAGGATCGTTTCATCTTGCGTTCGGGCAAGCCGGAGAGGAGAAGAGGGGAGACCGGTTTATCCTAACCGAATTCTGGATTGGATATCTGAGGAAACTAACCGTTCGTTTGCACATAGGAGCTTTCCCCCTTCGCCTTTCCACCAGTTTCCAGG

Function

symbol description
fbxw7 Acts upstream of or within angiogenesis; negative regulation of myelination; and regulation of signal transduction. Is expressed in glioblast (sensu Vertebrata); neural tube; neuroblast (sensu Vertebrata); spinal cord; and trunk. Orthologous to human FBXW7 (F-box and WD repeat domain containing 7).

GO:

id name namespace
GO:0045746 negative regulation of Notch signaling pathway biological_process
GO:0001525 angiogenesis biological_process
GO:0031641 regulation of myelination biological_process
GO:0031642 negative regulation of myelination biological_process
GO:0032006 regulation of TOR signaling biological_process

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko04131 Membrane trafficking
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-090313-79 Acts upstream of or within angiogenesis; negative regulation of myelination; and regulation of signal transduction. Is expressed in glioblast (sensu Vertebrata); neural tube; neuroblast (sensu Vertebrata); spinal cord; and trunk. Orthologous to human FBXW7 (F-box and WD repeat domain containing 7).

Ensembl:

ensembl_id ENSDARG00000060994

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001998 False 2256 mRNA 0.53 11 24870661 24918686
TCONS_00001999 False 3312 mRNA 0.55 13 24870661 25144439
TCONS_00002951 False 743 lncRNA 0.53 2 24967346 25024503
TCONS_00002952 True 419 lncRNA 0.50 1 25143964 25144382

Neighbor

gene id symbol gene type direction distance location
XLOC_001235 BX511127.1 coding downstream 45398 24825147 ~ 24825263 (-)
XLOC_001234 NA coding downstream 263899 24602332 ~ 24606762 (-)
XLOC_001233 gatb coding downstream 311823 24520503 ~ 24558838 (-)
XLOC_001232 sh3d19 coding downstream 407970 24376698 ~ 24462691 (-)
XLOC_001231 lrba coding downstream 520872 23919418 ~ 24349789 (-)
XLOC_001237 tmem154 coding upstream 9637 25154076 ~ 25177225 (-)
XLOC_001238 trim2a coding upstream 178006 25322445 ~ 25370281 (-)
XLOC_001239 fhdc1 coding upstream 255075 25399514 ~ 25438934 (-)
XLOC_001240 arfip1 coding upstream 298260 25442699 ~ 25486571 (-)
XLOC_001241 sfrp2 coding upstream 346885 25491324 ~ 25496133 (-)
XLOC_001230 NA non-coding downstream 959655 23908717 ~ 23911006 (-)
XLOC_001229 NA non-coding downstream 1086892 23751953 ~ 23783769 (-)
XLOC_001225 NA non-coding downstream 1423361 23445485 ~ 23447300 (-)
XLOC_001242 AL935184.2 non-coding upstream 411286 25555725 ~ 25558287 (-)
XLOC_001245 NA non-coding upstream 564873 25709312 ~ 25714494 (-)
XLOC_001247 CU929073.1 non-coding upstream 718527 25862966 ~ 25863639 (-)
XLOC_001256 NA non-coding upstream 1038960 26183399 ~ 26185720 (-)
XLOC_001257 NA non-coding upstream 1099066 26243505 ~ 26248287 (-)

Expression


Co-expression Network