XLOC_002440 (nr2f1b)


Basic Information

Item Value
gene id XLOC_002440
gene name nr2f1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 43797130 ~ 43808197 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004581
GACCACCAGTGAAGCGCGCGCGTGAGAAGAACACAGAGTAAAAGTGCGGTCATGTACATCTCCATCATGCCGAAAAGAGTTGAGTTTTCACGGATGCTCCAAATAAATCTGTTATAGTCAGCAATCCTCCACTCATGCTCCTGTCAATCATGCCGACAGCGCGGTATCTGTACTCCCATTGGATCTGATTCATCTGGGGTTTCCGATCGTCCCTTTTACGCACGGAGTTGCTTCAAATCGCGCGTTTAGGGAAATGCGTGGATAAAACCGGCTTTCTTGGTTAATTCGCGTAAAAGATTCCAGCCATGGCCATGGTGGTGAGCGCGTGGAGAGATCCGCAGGAGGAGCTGGCAGCGGTGGATGATCAGAGCGCGGCCGGGAGAGAGCACCTCCAGCACCGGCACTCGCCGAAGTCCGCGGAGGAAAAAGCGCAGATCGCGGCGCAAAACCAGCAGCACGTCGAGTGTGTGGTGTGCGGGGATAAATCCAGCGGGAAGCACTACGGACAGTTCACCTGCGAGGGATGCAAAAGTTTCTTCAAGCGAAGTGTCCGGCGGAATTTATCGTACACGTGCCGCGCCAACAGAAACTGCCCGGTGGATCAGCACCACCGCAACCAGTGCCAGTACTGCCGCCTGAAGAAGTGCCTGAAAGTGGGCATGAGACGCGAAGCGGTTCAGCGAGGCAGAATGCCACCGAACCAGCCGAACCCGAGCCATTACGCGCTGACCAACGGAGATCACCTGAACGGCCAGTGCTATTTATCCGGATACATATCGCTTCTCCTCCGGGCCGAGCCCTATCCAGCCTCGAGATACGGCAACCAGTGCATGCAGTCCGGCAACATCATGGGCATAGAGAACATCTGCGAGCTGGCGGCCCGTCTGCTCTTCAGCGCGGTGGAGTGGGCCAGGAACATCCCGTTCTTCCCCGATCTGCAAATCACGGATCAGGTGTCTCTGCTCAGACTCACCTGGAGCGAGTTGTTCGTGCTGAACGCCGCGCAGAGCTCTATGCCGCTGCACGTGGCCCCTCTGCTGGCCGCCGCAGGCCTGCACGCGTCGCCGATGTCCGCGGACCGAGTCGTGGCCTTCATGGATCATATTCGCTTCTTCCAGGAGCAGGTGGAGAAACTGAAGGCCCTGCAGGTGGACTCCGCCGAATACAGCTGTGCCAAAGCCATAGTGCTGTTCACCTCAGATGCATGCGGCCTTTCAGACATCCCGCACATTGAAGGTCTCCAGGAGAAATCTCAATGTGCCCTGGAGGAGTATGTGCGGAGTCAGTACCCGAACCAGCCCACCCGCTTCGGCAAACTGCTGCTCCGGCTCCCGGCGCTCCGCATGGTCTCCTCCTCCGTCATTGAACAGCTTTTCTTCGTTCGGCTGGTGGGAAAAACACCCATTGAGACGCTCATCAGGGATATGCTGCTATCTGGGAGCAGTTTCAACTGGCCCTACATGCCTATTCAATAACATTTGGTGAGCATTTACAGACTCTAAAGAAAACTAAACAGGCAAGGACGACGCAGAAAGTCGGACTCTCTTaacatcacactgtaaaaaaatccacgGTTTCcgtattttaagtgtttattgcTTTTTATGGATTTGTATAAGGTCTTTGCTACCCCAGCAAGCATCTTTGTTCTTAAAAGATGTctatagacgtctaaacatagtcgtattggctaaaacaaagctaaatttgggctgtcagacGTCCAAGAATAAGCCAAAACTAATCATCAAATAAAACCGGGATAACAGAAATAATGACTAcaaatataaagtctgtctaatctgtctatttgacgactagtctagttttgggctatttttagatgtctattagattttcaccgaCAAGTTTAGCCTTTGTttaagccaagctgtctacgtttagatgtctattagacgtctgttaaacacaaaatggtTTGCtgcgacttttgatgttgaaagttCAACCCTACagttcaacaaagtgacttttattgacattttagtagtttggaaaaaatatctagaagtaatatagagagaaataattctgtaaaatgaaataaaatgtactggcagtaaATTAGGCTATAAGGTATTTAGcccaccaacccagacaatacagcactgcaaactattaaagAGGTTCATGAAAGTCACTTTTTGAGCTTTTGAATGTTAAAaattgttggaggaaagatcaagatcccaattcaaaagcataaataaacaaggaaagtaaaataaaataaaaacatgaaacacaaaatacgaaaaactgctaatttacggatttTCTTTTACAGTGCAGGTTACAAAAATGTGACAATGTGAATTTATCTTTGCTCTTTTTGTCCTTGCTTTTAACAGTCAATCATGATTTGTGTCTTATATAACCTTTATTTCTTCTGCATTGTAATGATccgtttaaagtgttttaaatcaaAATGCATAATGTCTtaatttagttagttagtaaTATGTTTTAACGGAGGGAACCAAATCACCATTATTGAAGTTTCCCTAAAGAAATACacaagttttgtttttaaccgAAGCGGAGACAATGGATTTAAcgattatttattttgctgtatttattttcCTGCTCATCGACCTCATGAACACGTGATCTAAACAATCAACACAGCACTTAAGGTTATGCATATTGGTGTATACTTTACAGTATTTTCCACTTCGATCCTGCAGGTTGATTATTTGGGGCTGTTGGATTTTATGTACGATGCAACATTTGATTAAACAATTAATCATTCCATGCGTAAA

Function

symbol description
nr2f1b Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in angioblast cell migration. Acts upstream of or within venous blood vessel development. Predicted to be located in nucleus. Is expressed in several structures, including basal plate midbrain region; midbrain neural keel; nervous system; pharyngeal arch; and vasculature. Human ortholog(s) of this gene implicated in Bosch-Boonstra-Schaaf optic atrophy syndrome. Orthologous to human NR2F1 (nuclear receptor subfamily 2 group F member 1).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030154 cell differentiation biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0048856 anatomical structure development biological_process
GO:1904888 cranial skeletal system development biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0001944 vasculature development biological_process
GO:0035476 angioblast cell migration biological_process
GO:0060841 venous blood vessel development biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0004879 nuclear receptor activity molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0003707 steroid hormone receptor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1438 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in angioblast cell migration. Acts upstream of or within venous blood vessel development. Predicted to be located in nucleus. Is expressed in several structures, including basal plate midbrain region; midbrain neural keel; nervous system; pharyngeal arch; and vasculature. Human ortholog(s) of this gene implicated in Bosch-Boonstra-Schaaf optic atrophy syndrome. Orthologous to human NR2F1 (nuclear receptor subfamily 2 group F member 1).

Ensembl:

ensembl_id ENSDARG00000017168

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004581 True 2786 mRNA 0.46 3 43797130 43808197

Neighbor

gene id symbol gene type direction distance location
XLOC_002439 NA coding upstream 271917 43518594 ~ 43525213 (+)
XLOC_002438 rasa1b coding upstream 346542 43406796 ~ 43450588 (+)
XLOC_002437 vcanb coding upstream 533245 43188678 ~ 43263885 (+)
XLOC_002436 xrcc4 coding upstream 612776 43088270 ~ 43184354 (+)
XLOC_002435 atg10 coding upstream 720923 43037064 ~ 43076207 (+)
XLOC_002441 NA coding downstream 20130 43828327 ~ 43938288 (+)
XLOC_002442 CR384089.1 coding downstream 185155 43993352 ~ 44024651 (+)
XLOC_002443 cldn5b coding downstream 186274 43994471 ~ 43996117 (+)
XLOC_002444 cryba4 coding downstream 233836 44042033 ~ 44051808 (+)
XLOC_002445 NA coding downstream 247552 44055749 ~ 44198211 (+)
XLOC_002433 NA non-coding upstream 976224 42819726 ~ 42820906 (+)
XLOC_002432 NA non-coding upstream 1051550 42741085 ~ 42745580 (+)
XLOC_002430 NA non-coding upstream 1065136 42729946 ~ 42731994 (+)
XLOC_002429 NA non-coding upstream 1073909 42720841 ~ 42723221 (+)
XLOC_002447 NA non-coding downstream 572785 44380982 ~ 44383459 (+)
XLOC_002453 BX569788.1 non-coding downstream 959191 44767388 ~ 44769521 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000158_01572487_01576220 NR2F1, NR2F2, NR2F1.L, NR2F1A, NR2F1B coding CI01000158 null 1571879 ~ 1576713 (+)