XLOC_005679 (abcc2)


Basic Information

Item Value
gene id XLOC_005679
gene name abcc2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 681628 ~ 711576 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011283
AACTCATCGTTCCTGCAGCGTGAGGACCCGGATCTGCCGGTGTGTGTGGAGAGGACGGTGCTGGTGTGGCTGCCGCTGGCCTTCCTCTGGATCTGCTCTCCATTTCACTTCAGGAGTTTCTGTCAGAAATCTGCCAAAGCTCCGGCGTCAGCGCTCTACTACTGCaaacagGTTGTGGCCGGTCTGCTGCTTCTGACGGCAGTTGCAGAGCTCGCTGTGACTCTCGGGGAAGACTTCGGTCCGTCCAGCGATGAAGATGCTCAGAAAAACCCTGCAGTTCTCTACACCAATCCTGTTCTGTTTGCTGTGtcatggatAGTGGTGATGTTGTGTCAGGAGTCGATGCGGCACCGGCTGATGTGTGTGGACTCCGGGAGCCTCTTCATGTTCTGGCTGCTGCAGGTGGTGTGTGCTGTTTTCCAGTTCCAGACGCTGCTGAGAGAAGCTCTCAGTcagGGGATCTCTGACGTGCCGCGCTTCTGCCTCTTCTACATCAGTTATGGGCTGCAGATCATCGCTCTGGTTCTATCCGCCATCGCTGACGTTTCACCTGAAGCCAAAAAAGTTGCAGAAACGAATCCTGAGGCTAAAGCCACGTTTCTCAGCAGAATCACCTTTAACTGGTTCAACAGCATGGTGTGGAAGGGCTTTAAAAGGCCTCTGGTTCAGGAGGACATGTGGGATCTGAACAAAAACGACTCCACACACTTCATCTGTCAGACGTTCGAGGACGTGATGGCCAAGGAGCTGAAGAAAGCCCGCAACAACCTACAGAAGAAGAAAAGCAAGAAACGCAAGACCGTAGATGCTGAGGGTCAGAACGGACTGGCCAAAGGGGTCAGTCAGGACGTGCTGGTCATGGAGACAGAAACTGAAAAAGAGagcaaaaagaagaagaagaagaagcagaaggACTCAGATTCAGACTATCCTCAGTCGTGGCTGGTTACTACCATAGTAAAATCATTTAAAGGTGTACTTCTGGAGTCTGCGCTCTTTAAACTGCTCCAGGATCTGCTGTCCTTCGCAAGCCCACAGCTACTCAAGTTAATGATCGCCTTCACTCAGAATAAAGACAGCTATGCGTGGACCGGTTACCTGTATGCGGTGCTGCTGGTGCTGGTGGCGTTCGTGCAGTCGGTGGTTCTACAGCAGTATTTCCAGCGATGCTTCATACTGGGAATGAAAGTTCGCACAGCTATCATGGCAGCTGTCTATAAGAAGGCGTTAGTTGTGTCCAATGACTCCCGGAAGGAGTCGACAGCTGGAGAGATTGTGAACCTGATGTCCGCAGACGCTCAGAGATTCAACGACGTCACCAACTTCATCCACCTGCTGTGGTCGTGTCCGCTTCAGATCGCGCTCTCCATCGCCTTCCTCTGGATCGAGCTCGGACCGTCCGTTTTATCCGGTCTGCTGGTGATGGTGCTGATGGTGCCCATTAATGGATGGCTGGCCACCAAATCCAGACAATTCCAGATGCAAAACATGAAATTTAAAGACTCTCGCATGAAAATAGTGAACGACCTGCTGAATGGAATTAAAATCCTGAAGTATTACGCCTGGGAAACATCCTTCGAGGCTCAGGTTCAGGAGATTCGGGAAAAAGAGCTGAAGGTGATGAGGAAATTCGCCTACCTGTCCTCCGTCTCCACGTTCATCTTCTCATGCGCTCCAGCTCTCGTTTCTCTGGCCACCTTcgctgtgtttgtgtctgtgagtCCTGATAATATTCTGGATGCAGAGAAAGCTTTCACCTCCATCTCTCTCTTCAATATCCTGCGATTCCCACTGGCCATGCTCCCACAGCTCATCTCCATCATGGTCCAGACGTCTGTATCTAAGAAGAGACTGGAGAAGTTTCTGAGCGGTGATGATCTGGACACAACGACAGTCACACATGACAGCAGCATCACCGCCGCAGTGAGCATGACCAACGGCACATACGCCTGGGAAAGAGACACAGAGCCAGTGCTCAAACAGGTTTCTCTGGACATTAAACCGGGTCGTCTGGTGGCCGTGGTCGGAGCAGTGGGTTCTGGGAAGACGTCACTTGTTTCAGCTCTGCTGGGAGAATTGCACAGCATCAAGGGAAACATTAACATCAACGGCTCGGTGGCGTATGTGCCTCAGCAGGCCTGGATCCAGAACGCCACATTAAAGGACAATATTTTATTCGGTTCTTCAGTGGATGAGGAGCGATATCAGTCTGTGATTAAAGCCTGCGCTCTCGGGCCAGACCTGGACCTGTTGCCGGGACGAGACCAGACCGAGATTGGAGAAAAGGGCATTAATCTGAGCGGTGGGCAGAAGCAGCGGGTGAGCCTGGCGCGGGCCGTCTACAGCTCTGCAGATGTGTATTTGCTGGATGATCCTCTGTCCGCCGTAGACTCACATGTGGGAAAACATCTGTTTGAGAAAGTGATCGGGCCCAATGGACTGCTCAGAGACAAGACTCGCATCTTGGTAACTCATGGAATCAGCTTCTTGCCGTATGTAGATGAGATTGTAGTGTTGGTGCATGGCGTCGTGTCTGAGATCGGATCATACGAAAGTCTTCGAGCCAGTAAAGGAGCTTTCTCTGAGTTTCTGGAGACGTACGGCAAAGACGAGAGCAACAAAGACAATGACAAAAAAGcagcagcagctcagacACCAGTGTATGAAGAGATTGAGACGCTGCCGGAGGGCTTGGAGACGCAGGCTGATGGATCTCCAGAAGACATTGTTTCCAGTACATTAAAGAGAGAAAACAGTCTGCGCCACAGCCAGCGGCACTCCAAGAGGAACGGAAGTGTGAAGGTCAGAAAAAACAGCTCTCTTCGCGCTCAGAAAGATCCGGAGGATAAGAAGGGTCAGCGCCTGATTGAGAAAGAGATGATGGAGACTGGAAGGGTGAAGTTTTCAGTGTATCTGCAGTACCTGAGCGCCATGGGCTGGTGGTACGTGGGCTTCAGCTTCGTCTTTTACTTCATCCAGAACGTGGCTGTGATCGGACAGAACCTGTGGCTCAGCGACTGGACCGACGATTCTATAGAGTATTTCAACCAAACCTACCCCAACCACATCAGAGACACCAGGATAGGGGTTTTTGGAGCCCTTGGATTAGCACAAGgtTTTCTGGTGTTTTTCGGGACTATACTCCTCGCTGATGGGTCCATCTCTGCATCCAGGACTCTACACACAAGCCTGCTGACTAACATTCTTAAAGTCCCCATGATGTTCTTCGACACCACACCTTCAGGACGAATTGTCAATCGATTTGCCAAGGATATATTCACTGTGGACGAGATGATCCCGATGTCCTTCAGGTCCTGGATCCTCTGTCTTCTTGGAGTTCTGGGAACTCTTTTCGTCATCTGTCTGGCTACTCCAATCTTCACTGCGGTTGTTGTACCGATGGCTGTTGTCTACTACTTTGTGCAGAGGTTTTACGTGGCCACGTCTCGGCAGCTCAGACGACTGGACTCGGTGTCTCGATCTCCCATATACTCACACTTTGGAGAAACCGTATCCGGCCTGTCCGTGATAAGGGCGTATGGACACCAGGACCGCTTCCTAAAGCACAACGAGCACACCATCGACCAGAACCTGAAGAGTGTTTATCCATGGATTGTTTCCAATAGGTGGTTGGCCATGCGTTTGGAGTCTCTGGGGAATCTGGTGGTGTTTTTCGCAGCTCTGTTTGCTGTCATCTCCCGAGACTCTCTGAACAGCGGACTGGTCGGACTGTCCATCTCATacgctttaaatGTGACGCAGACGCTGAACTGGCTGGTGAGAATGACGTCTGAACTGGAGACCAACATCGTAGCTGTGGAAAGAGTGAGAGAGTATGCCGAGATCCAAAATGAGgCTCCGTGGGTCACCAGTGTTCGTCCTCCTGATGATTGGCCCTCTGCTGGAAACATCCGCTTTGAAGACTACAAAGTTCGCTACCGTCCAGAACTGGAGCTCGTCCTCCACGGGGTCACCTGTGACATTCAGAGCACAGAGAAGATTGGCATCGTGGGTCGCACTGGAGCAGGTAAATCCAGCCTGACCAACTGCTTGTTCCGCATCGTTGAAGCTGCGGACGGTCGAATCCTCATCGATGATATCGACATTGCCACGCTGGGACTCCACGATCTGCGCAGTCGACTGACCATCATTCCTCAGGACCCAGTGCTGTTCTCCGGGACGCTGCGGATGAATCTGGACCCGTTTCAGACCTTCAGCGATGCGGAGATCTGGAGTGTCCTGGAGCTGGCCCATCTCAAAGAATACGTCAGGGGTTTACCAACAGGACTTGAACACGAGGTGTCGGAGGGAGGAGAGAATCTGAGtctgGGTCAGAGGCAGCTGTTGTGTTTAGCTCGAGCTCTGCTTCGTAAATCTCGAATCCTGATTCTGGATGAAGCAACAGCAGCGGTGGATCTGGAGACAGACGATCTCATCCAGAGCACCATCCGCAGAGAGTTCTCCCACTGCACCGTCCTGACCATTGCACACCGCCTCAACACCATCCTggacagctcacgAGTGATGGTGTTGGATTCTGGAAAGATCGTGGAGTTTGATTCTCCCAATGAACTGCTGAGCAAACCTGGACATTTCTCCTCCATGGCTGAAGATGCTGGAATCAGAAGAGAAGAAGAGCAGAGCCAATCATACGTCTTCTGAACGCTTCATTTGCATAAAGatcaaacattattaaatattaaggaaTTGTATTACTTCTTTCTAATCCAGCTGTTTTTGTTGTAGTCTTTTATTTTAACCAGctttttatgttgttattattattattttgcatttatgttgttgttgttgtattgtgACAATAaagtgtattaaattataa

Function

symbol description
abcc2 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of plasma membrane. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder (multiple); carcinoma (multiple); drug-induced hepatitis; leukemia (multiple); and non-alcoholic fatty liver disease. Orthologous to human ABCC2 (ATP binding cassette subfamily C member 2).

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016324 apical plasma membrane cellular_component
GO:0005524 ATP binding molecular_function
GO:0022857 transmembrane transporter activity molecular_function
GO:0008514 organic anion transmembrane transporter activity molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0042626 ATPase-coupled transmembrane transporter activity molecular_function

KEGG:

id description
ko02010 ABC transporters
ko04976 Bile secretion
ko01524 Platinum drug resistance
ko01523 Antifolate resistance
ko02000 Transporters

ZFIN:

id description
ZDB-GENE-040426-1523 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of plasma membrane. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder (multiple); carcinoma (multiple); drug-induced hepatitis; leukemia (multiple); and non-alcoholic fatty liver disease. Orthologous to human ABCC2 (ATP binding cassette subfamily C member 2).

Ensembl:

ensembl_id ENSDARG00000014031

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011283 True 4843 mRNA 0.51 31 681628 711576

Neighbor

gene id symbol gene type direction distance location
XLOC_005678 cutc coding upstream 3172 674351 ~ 678456 (+)
XLOC_005677 CU462915.1 coding upstream 10882 669177 ~ 670746 (+)
XLOC_005676 tp53bp2a coding upstream 17156 646700 ~ 664472 (+)
XLOC_005675 NA coding upstream 120643 553591 ~ 560985 (+)
XLOC_005674 wu:fc17b08 coding upstream 135975 534453 ~ 545653 (+)
XLOC_005680 cox15 coding downstream 2365 713941 ~ 724385 (+)
XLOC_005681 nrxn1b coding downstream 21451 733027 ~ 811276 (+)
XLOC_005682 gsta.2 coding downstream 118009 829585 ~ 832331 (+)
XLOC_005683 AL929536.3 coding downstream 123814 835390 ~ 840787 (+)
XLOC_005684 gsta.1 coding downstream 132567 844143 ~ 852506 (+)
XLOC_005670 CABZ01061569.1 non-coding upstream 243166 438347 ~ 438462 (+)
XLOC_005661 NA non-coding upstream 412311 268042 ~ 269317 (+)
XLOC_005659 NA non-coding upstream 439009 242088 ~ 242619 (+)
XLOC_005656 NA non-coding upstream 471896 202760 ~ 209732 (+)
XLOC_005685 NA non-coding downstream 147481 859057 ~ 861896 (+)
XLOC_005687 NA non-coding downstream 261433 973009 ~ 986263 (+)
XLOC_005701 CABZ01044297.1 non-coding downstream 1053931 1765507 ~ 1765622 (+)
XLOC_005705 NA non-coding downstream 1271735 1983311 ~ 2033043 (+)
XLOC_005706 NA non-coding downstream 1438194 2149770 ~ 2153016 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000005_06623484_06646729 ABCC2 coding CI01000005 null 6623344 ~ 6646729 (-)