CI01000050_04943326_05005151 (NTRK2, NTRK2A)


Basic Information

Item Value
gene id CI01000050_04943326_05005151
gene name NTRK2, NTRK2A
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000050
NCBI id null
chromosome length 7556436
location 4943270 ~ 5005151 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000050_04943326_05005151.mRNA
ATGCGCTGCGCATCATCCAGCGCTCGCGCTCTCTCACTTCAGCACTCGCGTTTCTCAAGAGCGCGTCTTCTGTCCTTCTCCGCTCACCCGGACGCGTCATTGAACGCCAGCATCATTCTAGGGGGTCTTAAATCTGGAGGCGAGGACCCGGGGATGAGCCTGCTGTCGAGGGGCTTCGGCATGTCGGGCTGGGGGCTCAGTTGGGTTCTGATGCTGCTCGCGCTCTGGAGGCCCGGTACCGCTTGTCCGGAGCCCTGCACGTGCACGGGCGTTCGGATCTCGTGCGTGGATGCGGAGCGCAGTATTGTGGCGTTTCCAATGCTGCAGTCCGAGGCAGAGATGGAGAATATCACAGACATATACATTTCAAATCAAAGCAGTTTCACATCCATTAATGAAAAAGATCTCAACTTATACCGCAGCCTCAGAAACTTAACTGTAACAAACACACGGCTCACATATATTTCGAGGCAGGCCTTTCAGAGCAACCTGAAACTACAATATCTGAATCTCAAAGAGAACAATCTGTCGTATCTATCCTGGAGGACGTTTCATCACTTAAACATTTCATACCTGTTGCTGGCAGGCAATCCTTTGCAGTGCTCATGTGAAAACGTGTGGTTGAAGCAGTGGAGAGGAGAGGAGGCTGAGGAGCTGCTGTGTGTGGAGGAGGGAGGAAAGAGGAGGGCTCTGTCTATGCTCACACTGCCTAACTGTGTTCTCCCCACTGTGACTCTCACTCCCACTAAAGTTACCATGAAGAAAGGGTTAAATGTGACGCTGATGTGCAACACCTCAGGAACGCCCACGCCTAGTCTCAACTGGAACACCTGCAAATTAAATTCAGCGTATGAGCAAGAACGCTCAGGTCAGATGTCAGAGCTCAAGCTCTTGAATGTCTCTTCACTGGACAACGGATGCAAAATCACCTGCAGATCTGATAACATGGTGGGAGAGTCTGAGGCGTCTGTGCATCTGGACATACTGTTTGCACCTGTAATCAGCAAGCTGATGGATGCTATCTCAGACCACCATTGGTGCATTCCCTTCAGCGTGTCGGGCAACCCAGAGCCTAAACTGAGCTGGTTATTAAACGACAAACCCGTGGAAGAGGGCAACTTTATCCATACCATGATCCACGATTATTCAGAGGGTGAATACCACGGTTGCTTACAGCTGGACAGTCCCACACACATTAACAATGGAAAGTACACGCTGCTGGCCAGTAATGCATACGGAGAGGACAGCAAGGCAGTATTCGCTCATTTCATGCATGAGCCGTGGAACGATGACACTCCTCTTGGACCGCCTGAGGAAAAAGTTGCTGTGTACGTGGTCGTGGGAATTGCAGCAATCACATTCACAGGCTTCATCTTGATGCTTGTCATTCTGAAGTTTGGACGCAACTCAAAGTTTGGAATCAAAGGTCCTTCCTCAGTCATCAGTAATGACGATGACTCTGCCAGTCCTCTTCATCATGTGTCCAATGGCTCTAACACACCCTCGTCCTCTGACATGAACGCGGACGCCGTCATCATTGGCATGACCAAGATTCCCGTCATAGAGAACCCGCAGTACTTCCGCAGCACCAGCAGTCTGCTCAAATCGGATACCTTTGTTCAACACATTAAGAGGCACAACATTGTACTGAAGAGGGAACTTGGAGAAGGAGCGTTTGGGAAAGTGTTCCTGGCCGAATGCTACAATCTGTCCACAGACCAGGATAAGATCTTAGTGGCTGTCAAGACATTGAAAGAGGCCAGTGAGAATGCCAGGAAGGACTTCCATCGTGAGGCTGAGTTGTTGACCAATCTGCAGCATGAGCACATTGTCACGTTCTACGGAGTGTGTGTGGAGAGCGATCCGCTCATTATGGTGTTTGAGTACATGAAGCATGGCGACCTCAACAAGTTCCTTAGGGCTCATGGTCCTGATGCAGTTCTGATGGCTGACGGACAGGTGCAGCAGCAGGCAGAGCTCACTCAGTCTCAGATGCTGCATATTGCGCAGCAGATCGCCGCAGGCATGGTGTATCTGGCATCCCAGCACTTTGTTCACAGAGACCTGGCCACACGAAACTGCCTAGTCGGGGAGAATCTCCTGGTGAAGATTGGAGACTTTGGAATGTCCCGAGATGTCTACAGTACGGATTACTATCGGGTTGGAGGTCACACCATGCTGCCAATCCGCTGGATGCCACCAGAAAGTATCATGTACAGGAAGTTCACCACAGAGAGTGATGTCTGGAGTCTGGGAGTGGTGCTGTGGGAAATCTTTACTTATGGGAAACAGCCCTGGTACCAACTGTCAAATAATGAGGTGATTGAGTGTATCACCCAAGGCCGTGTACTGCAGCGACCCCGGACCTGTCCAAAGGAGGTGTATGACTTGATGTTGGGATGCTGGCAGAGAGAACCACACACCCGACTCAACATTAAAGAGATCCATAACCTTCTCCTCAACCTAGCCAAGGCATCACCGTGTAAATGTCTAAATACTTTGGCAACAGGATTGTGTCCAGTGACTATGAATTATGTACTTCTTAACAAAAAACGGATTGTATGGAAGAGCCGTACTCAAGTGACTATAATTTTGCTTACGGAGAACAAAATCCCCAATGGTTGACCATCCTAAACTTCTGGACCAAGTTCACACCTGCAAATTCCAGTTCAGTGAATAAA

Function

symbol description
ntrk2a Predicted to enable brain-derived neurotrophic factor binding activity and brain-derived neurotrophic factor-activated receptor activity. Predicted to be involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; regulation of intracellular signal transduction; and trans-synaptic signaling by neuropeptide, modulating synaptic transmission. Predicted to act upstream of or within cell differentiation; nervous system development; and protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in axon. Predicted to be integral component of plasma membrane. Is expressed in endoderm; mesoderm; nervous system; neural tube; and pharyngeal epithelium. Human ortholog(s) of this gene implicated in Alzheimer's disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2).
ntrk2 Enables brain-derived neurotrophic factor-activated receptor activity; neurotrophin binding activity; and protease binding activity. Involved in brain-derived neurotrophic factor receptor signaling pathway. Acts upstream of or within negative regulation of amyloid-beta formation. Is integral component of plasma membrane. Part of receptor complex. Implicated in Alzheimer's disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Biomarker of bipolar disorder; idiopathic pulmonary fibrosis; major depressive disorder; and schizophrenia.

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process

KEGG:

id description
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000050_04943326_05005151.mRNA True 2681 mRNA 0.50 18 4943270 5005151

Neighbor

gene id symbol gene type direction distance location
CI01000050_04844985_04863467 NAA35 coding downstream 79803 4844985 ~ 4863467 (-)
CI01000050_04821454_04823915 NA coding downstream 119355 4821121 ~ 4823915 (-)
CI01000050_04786504_04807380 NA coding downstream 132918 4786316 ~ 4810352 (-)
CI01000050_04781467_04784451 NA coding downstream 158683 4781003 ~ 4784587 (-)
CI01000050_04732489_04733933 NA coding downstream 209337 4731986 ~ 4733933 (-)
CI01000050_05008397_05010031 NA coding upstream 2590 5007741 ~ 5010040 (-)
CI01000050_05128945_05154128 RASEF coding upstream 123016 5128167 ~ 5154512 (-)
CI01000050_05206986_05209502 NA coding upstream 201383 5206534 ~ 5209502 (-)
CI01000050_05275592_05286286 NFU1 coding upstream 270417 5275568 ~ 5286617 (-)
CI01000050_05413540_05419241 NA coding upstream 408359 5413510 ~ 5419241 (-)
G215910 NA non-coding downstream 20050 4922751 ~ 4923220 (-)
G215904 NA non-coding downstream 31234 4911765 ~ 4912036 (-)
G215872 NA non-coding downstream 35119 4906541 ~ 4908151 (-)
G215880 NA non-coding downstream 63114 4879872 ~ 4880156 (-)
G215839 NA non-coding downstream 167099 4773378 ~ 4776171 (-)
G215883 NA non-coding upstream 6570 5011721 ~ 5015987 (-)
G215886 NA non-coding upstream 29754 5034905 ~ 5046046 (-)
G215950 NA non-coding upstream 85095 5090246 ~ 5121659 (-)
G215915 NA non-coding upstream 382819 5387970 ~ 5388245 (-)
G216069 NA non-coding upstream 396223 5401374 ~ 5402011 (-)
CI01000050_04564233_04580815 KANSL3 other downstream 330378 4563687 ~ 4581278 (-)
G214436 NA other downstream 1354213 3525816 ~ 3589057 (-)
CI01000050_03491159_03514757 NA other downstream 1432479 3491088 ~ 3514757 (-)
G214314 NA other downstream 1519013 3413448 ~ 3424257 (-)
G214027 NA other downstream 2370368 2557166 ~ 2572902 (-)
G215935 NA other upstream 43765 5048916 ~ 5073109 (-)
G216093 NA other upstream 484406 5489557 ~ 5552103 (-)
G216408 NA other upstream 1350866 6356017 ~ 6356511 (-)
G216931 NA other upstream 2158944 7164095 ~ 7165401 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00007839 LOC108438531,LOC107714007,LOC108269325,LOC107654144 coding CM030123.1 CM030123.1 32325622 ~ 32356646 (+)