XLOC_002409 (adrb3b)


Basic Information

Item Value
gene id XLOC_002409
gene name adrb3b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 41199660 ~ 41214668 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004534
GAACAAGAGCGCACGATAATGGATGATAAGAGTTTGGAAGAACTTCTCAACAAGCCTGAATTATTGAGGAGGAGGATTTGAGGGAGGAAGATCCAATCTGGGACATTATCCAAGCATGCAAAGGACTACAGAAGTCTTTAGCAGAATTTTGGGACTGACTAATCCAGTGTCTATTTCTCTTGATCACTGAAAGCTTCCTCTCAGGATGAGCGCCAACACCACCACCCTGATTCCTGAAGATGTCAAGCCCCTGCTGGTTCTTCCTCTGGCGTTGGTCATCTTCTTGACGGTGATTGGAAACCTGCTGGTCATCCTGGCGATCGCCCGCACCCCTCtcctccacaccaccaccaatgtCTTCATCATCTCTATGGCATTCGCTGATCTCATTATGGGCTGTGTGGTCCAGCCTTTAGGACTCAGTATGGTGGTGGCTGGGAAATGGGTTTTGGGGAACCCTATGTGTGACCTGTGGACGTCTTTAGACGTGTTCTGCGTCACCGCTAGCATTGAGACATTGTGCGCTATCGCTGTTGAGCGATACATTGCGATTACCAGACCTCTGGAGCATCAGGTACTGTTGGGAAAACGCAGAGCCGCCTACATCGTATGCACAGTGTGGATCGTGTCATCCTTAGTTTCCTTCGTGCCAATAATGAACCATAATTCTCGTGCAAATTATTTAGCAGCAAACGACTGCTACAACAACTCGGAGTGCTGCGATTTCCATACTAACCAGCACTACGCCATCTTCTCCTCTGTGGTTTCCTTCTATGTGCCTCTTCTTGTTATGGTGTTTCTGTACGGGAAGGTGTTTGCCATTGCAAACAAGCAGTTGAAACTCATCGGTAAGGACAGACTTCGTTTTCTGAGCTCTTGCAATGAAGACTCTTGTGAAATTCCTGAAGGTTCGGCTCGAAGTTACAGTCGGAGAACAACAAAGCATGTCGTGAAAGAACACAAGGCGCTCAAGACTCTAGGGATTATCATGGGCATCTTCAGTCTCTGTTGGCTGCCCTTCTTCATCTTCAATATCATCAAAAGTTTTAATCCTGAAGTGCCAACACAGCTTGTGTTTCTCTTGTTGAACTGGCTGGGCTACGCCAACTCAGGCCTGAACCCAATCATCTACTGCCACAGTCCTGAGTACCGCAACGCTTTCTTTAATCTCTTAGGGTGCAAAAAACCCAAGCATTTTAACCAAACCACCGTGAACAAACATCTACAAAGCTTCACCTCGTGCATCCAGAGCAACAGTTCGGTAAGAATGGATTGCATGGGTCACAAAGATCCAATTGCACGGGGCGGGAACACTTGCTCTGACATGAGCTCAGTTTTAAAAGGAGAAGAGGTAGAAATACAGCCTCACAATGACTCGACAATGACGATGATCAATCTAGCAGAGATGTTGAAGggcCACTGAAGATGGGAAACAGACCCAGTGCTCAAGAGAATTAACCATAATGTCATGCTTTTCAAGCGGACCCTGACTGCATTTCATGCAAACCACGTGCAAAGGCAAAATGGACAGCTTTTAAAGTAAAGAGCAGCGAAGTGGGAAAGTGATATCGAGAACAAACCGTGACGAAAATGATCATGCACTGACTGATTCTTGAACTTTACACAGAACGGAAATTGAAGTCTTAAAATTGCATCTTTTCACCTCACAAAccatc

Function

symbol description
adrb3b Predicted to enable beta3-adrenergic receptor activity; epinephrine binding activity; and norepinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; obesity; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3).

GO:

id name namespace
GO:0007186 G protein-coupled receptor signaling pathway biological_process
GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure biological_process
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004930 G protein-coupled receptor activity molecular_function
GO:0015052 beta3-adrenergic receptor activity molecular_function
GO:0051379 epinephrine binding molecular_function
GO:0051380 norepinephrine binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-081022-154 Predicted to enable beta3-adrenergic receptor activity; epinephrine binding activity; and norepinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; obesity; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3).

Ensembl:

ensembl_id ENSDARG00000052919

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004534 True 1676 mRNA 0.46 3 41199660 41214668

Neighbor

gene id symbol gene type direction distance location
XLOC_002408 anxa4 coding upstream 6779 41159241 ~ 41192881 (+)
XLOC_002407 antxr1b coding upstream 152885 40973524 ~ 41046775 (+)
XLOC_002406 CU571179.1 coding upstream 234848 40939664 ~ 40964812 (+)
XLOC_002405 trim69 coding upstream 347983 40836378 ~ 40851677 (+)
XLOC_002404 si:ch211-139n6.3 coding upstream 399803 40792078 ~ 40799857 (+)
XLOC_002410 prlhr2b coding downstream 37857 41252525 ~ 41260567 (+)
XLOC_002411 CABZ01049847.1 coding downstream 335151 41549819 ~ 41609165 (+)
XLOC_002412 lrrc75bb coding downstream 453815 41668483 ~ 41735503 (+)
XLOC_002413 rnf34b coding downstream 550948 41765616 ~ 41817109 (+)
XLOC_002414 BX005006.1 coding downstream 625251 41839919 ~ 41840033 (+)
XLOC_002398 BX001050.2 non-coding upstream 450762 40747873 ~ 40748898 (+)
XLOC_002380 CR396590.1 non-coding upstream 559856 40638776 ~ 40639804 (+)
XLOC_002376 CR396590.3 non-coding upstream 589707 40609461 ~ 40609953 (+)
XLOC_002375 CR396590.7 non-coding upstream 590943 40607701 ~ 40608717 (+)
XLOC_002417 NA non-coding downstream 768329 41982997 ~ 41986283 (+)
XLOC_002424 NA non-coding downstream 1255948 42470616 ~ 42477259 (+)
XLOC_002429 NA non-coding downstream 1506173 42720841 ~ 42723221 (+)
XLOC_002430 NA non-coding downstream 1515278 42729946 ~ 42731994 (+)

Expression


Co-expression Network