XLOC_005673 (degs1)


Basic Information

Item Value
gene id XLOC_005673
gene name degs1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 502230 ~ 514843 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00011276
TCAGTCTCCGCCCGCCGTTCGTCACTCTGCGTAGTTCACGTACAGTCGGAAGATCTTCTGGAAGGAAGGAGGCTCAATGAGGATGATGAGGGACGGTCGCAGACATTAGATCCGCTTAAGGAAGCCGATCATTTCCTGACTAACACATCTAGAGAAAACCCCCCGCAAAATAATCGCTAGATCAGCGCCAAAATGGGGAACCGCGTGGCGCGCGAGGATTTCGAGTGGGTTTACACGGACCAGCCGCACGCCGACCGGAGGAAAGAGATACTGGCTAAATACCCAGAGATCAAGTCTCTGATGGGCCCTGACCCCAGGCTCAAATGGATAGTCAGCACGATGGTGGTTGTCCAGTTTTTGGCTTTCTACCTGGTGAAGGATCTGTCCTGGAAATGGGTGTTTTTCTGGACGTATGCATTTGGAAGTTGCATAAACCATTCAATGACACTAGCCATTCACGAAATCTCTCACAACACTGCTTTCGGCAACAACCGAGCCAAGTGGAACCGCTGGTTCGCCATTTTCGCCAATCTGCCTATAGGACTACCGTACTCTGCGTCGTTTAAACGCTACCATCTGGACCACCACCGCTACTTGGGTGGAGATGGTGTGGACGTGGACATCCCCACTGACTTTGAGGGTTGGTTTTTTTGCACGCGTATGCGCAAGCTGATCTGGATCATGTTCCAGCCGCTGTTTTACGCCATCCGGCCGCTCTACATCAACCCCAAACCCATCAGCCAGCTGGAGCTCCTGAACGTGGCCATCCAGCTGTCCTTCAACGCGCTCCTCTACTGGAGCTGGGGCGCCAAACCTGTGGTCTACATGATGATGGGCTCGATGCTGGGCATGGGTCTCCATCCCATCTCAGGACACTTCATCGCTGAACATTACATGTTCCTCAAAGGCCACGAGACCTACTCTTACTACGGCTCTCTGAACCTGCTGACGTTCAACGTCGGCTACCATAACGAGCATCACGACTTCCCTAGCATTCCCGGACGACGACTACCAATGGTGAAAGAGATCGCATCTGAGTACTACAGAGATCTGCCGTGCTACAGCTCCTGGATAAAAGTGCTGTACGACTTCATCATGGACGACCAGTTGAGTCCGTATTCACGCGTCAAGCGAAAACTGGTCGGAGACGTCAAGCAGGAGTGAGCAAACACACTGCGGCACACACACAGGCTTTTAGCAtacagcacattgattttaatGCTTCACCAAACCCTCTGAGCGTTTGTGTTCTCACGCTCTGAAGATCCGGACTCTTCTATTAATGCAGCAGGAATCATGACACCACACGCTTTAATCATGTGTATGATGGAGCAGGTCATGTTCATGTAGCTCTACATGTTCAGTGTTCTTCCTCTTCTGGAGTGTTTTACAGGAGCTGTTGATGGAGCGAGCGCAGTGTGTCTGGACTGTGTGCTCATCTCTCTGCTCGTCttcattatttcaacacttttatATTTCACATCAACTAAAAACAGCCTTACTGATATGGAGTCTGATTGTTACCGATGTTAATAGAAAGTAAATCTCTATATTCTCTA
>TCONS_00011277
GGGACGGTCGCAGACATTAGATCCGCTTAAGGAAGCCGATCATTTCCTGACTAACACATCTAGAGAAAACCCCCCGCAAAATAATCGCTAGATCAGCGCCAAAATGGGGAACCGCGTGGCGCGCGAGGATTTCGAGTGGGTTTACACGGACCAGCCGCACGCCGACCGGAGGAAAGAGATACTGGATTTCCTCAAGGAGTCTGAATATATGCCCACAAGCTCATAAATGACTGTTATTACTAATGAATCATGGGATTATTAccagCTAAATACCCAGAGATCAAGTCTCTGATGGGCCCTGACCCCAGGCTCAAATGGATAGTCAGCACGATGGTGGTTGTCCAGTTTTTGGCTTTCTACCTGGTGAAGGATCTGTCCTGGAAATGGGTGTTTTTCTGGACGTATGCATTTGGAAGTTGC

Function

symbol description
degs1 Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in nervous system; neural crest; notochord; pronephric duct; and yolk syncytial layer. Used to study hypomyelinating leukodystrophy. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human DEGS1 (delta 4-desaturase, sphingolipid 1).

GO:

id name namespace
GO:0046513 ceramide biosynthetic process biological_process
GO:0006629 lipid metabolic process biological_process
GO:0030148 sphingolipid biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0016491 oxidoreductase activity molecular_function
GO:0042284 sphingolipid delta-4 desaturase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-5283 Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in nervous system; neural crest; notochord; pronephric duct; and yolk syncytial layer. Used to study hypomyelinating leukodystrophy. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human DEGS1 (delta 4-desaturase, sphingolipid 1).

Ensembl:

ensembl_id ENSDARG00000007347

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00011276 False 1559 mRNA 0.50 3 502230 514843
TCONS_00011277 True 420 processed_transcript 0.49 3 502319 511139

Neighbor

gene id symbol gene type direction distance location
XLOC_005672 fbxo28 coding upstream 11661 482911 ~ 490569 (+)
XLOC_005670 CABZ01061569.1 coding upstream 63768 438347 ~ 438462 (+)
XLOC_005669 lgi1a coding upstream 72087 421231 ~ 430143 (+)
XLOC_005668 CU570800.2 coding upstream 84602 416648 ~ 417628 (+)
XLOC_005667 CU570800.3 coding upstream 89613 411607 ~ 412617 (+)
XLOC_005674 wu:fc17b08 coding downstream 19610 534453 ~ 545653 (+)
XLOC_005675 NA coding downstream 38748 553591 ~ 560985 (+)
XLOC_005676 tp53bp2a coding downstream 131857 646700 ~ 664472 (+)
XLOC_005677 CU462915.1 coding downstream 154334 669177 ~ 670746 (+)
XLOC_005678 cutc coding downstream 159508 674351 ~ 678456 (+)
XLOC_005661 NA non-coding upstream 232913 268042 ~ 269317 (+)
XLOC_005659 NA non-coding upstream 259611 242088 ~ 242619 (+)
XLOC_005656 NA non-coding upstream 292498 202760 ~ 209732 (+)
XLOC_005653 NA non-coding upstream 479055 20646 ~ 23175 (+)
XLOC_005685 NA non-coding downstream 344214 859057 ~ 861896 (+)
XLOC_005687 NA non-coding downstream 458166 973009 ~ 986263 (+)
XLOC_005701 CABZ01044297.1 non-coding downstream 1250664 1765507 ~ 1765622 (+)
XLOC_005705 NA non-coding downstream 1468468 1983311 ~ 2033043 (+)

Expression


Co-expression Network