GENE ID: ENSDARG00000004023


Symbol Location Gene type Genome version Species
isl1 5: 40728613 ~ 40734045 (-) protein_coding GRCz11 Danio rerio

  • PPI (protein-protein interaction) results are shown above.
  • Green is ENSDARG00000004023 (isl1), yellow represents other genes.
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  • MARKER



    EXPRESSION


    Dataset ID Tissue / Organ Experiment type Sample Cell type Marker class Evidence
    PRJNA564810 (2dpf) embryo baseline 2dpf, a single-cell transcriptome atlas for zebrafish development Neuron (cluster: 8)
    marker
    DOI:10.1093/g3journal/jkac062
    GSE148591 (6mpf) pituitary baseline 6mpf, male, Sox17:CreERT2 Isl1+ group (cluster: 11)
    marker
    DOI:10.1126/science.aba4767
    GSE148591 (3mpf) pituitary transplant 3mpf, graft transplantation during early embryogenesis Isl1+ group (cluster: 12)
    marker
    DOI:10.1126/science.aba4767
    GSE175929 (5mpf) retina baseline 5mpf, GFP-positive cells collected from two transgenic zebrafish, Tg(rho:EGFP)ja2Tg and Tg(gnat2:EGFP)ja23Tg Bipolar cells (cluster: 13)
    marker
    DOI:10.1016/j.cell.2016.07.054, DOI:10.1038/s41598-021-96837-z
    PRJNA610520 (3.5dpf) caudal hematopoietic tissue baseline 3.5dpf, the mixture of same amount of kdrl:mCherry+ cells, CD41:GFP+ cells and double negative cells. Neuron (cluster: 13)
    potential marker
    NA
    GSE173972 (HET, ezh1+|-) embryo hematopoietic 1.25dpf, Kdrl-positive embryos Epithelial cells (cluster: 4)
    potential marker
    NA
    GSE173972 (KO, ezh1-|-) embryo hematopoietic 1.25dpf, Kdrl-positive embryos Epithelial cells (cluster: 4)
    potential marker
    NA
    GSE106587 (WT) embryo baseline 12hpf, 6 somites, wild-type TLAB embryo Endoderm (cluster: 10)
    Placode (cluster: 15)
    potential marker
    potential marker
    NA
    NA
    GSE126647 (control) embryo baseline 1.17dpf, control nkx2.5:ZsYellow+ cells Endothelium (cluster: 8)
    potential marker
    NA
    PRJNA656271 (24hpf) embryo baseline 24hpf, FACS-isolated EGFP+ cells
    PRJNA656271 (1.5dpf) embryo baseline 1.5dpf, FACS-isolated EGFP+ cells
    PRJNA656271 (2dpf) embryo baseline 2dpf, FACS-isolated EGFP+ cells
    GSE158142 (12hpf) head baseline 12hpf, 6 somites, untreatment Prechordal plate,polsterq (cluster: 14)
    potential marker
    NA
    GSE158142 (14hpf) head baseline 14hpf, 10 somites, untreatment Placode (cluster: 14)
    potential marker
    NA
    GSE158142 (16hpf) head baseline 16hpf, 14 somites, untreatment Prechordal plate,polster (cluster: 15)
    potential marker
    NA
    GSE158142 (18hpf) head baseline 18hpf, 18 somites, untreatment
    GSE158142 (1.5dpf) head baseline 1.5dpf, untreatment Neuron (cluster: 12)
    potential marker
    NA
    PRJNA415636 (pancreas, liver) hepatopancreas baseline adult, Zebrabow M, pancreas and liver Pancreas endocrine cells (cluster: 1)
    Pancreas endocrine cells (cluster: 3)
    potential marker
    potential marker
    NA
    NA
    GSE150498 (DSS treated) intestine disease 6dpf, DSS treated
    GSE150498 (nod2-|-, untreated) intestine disease 6dpf, nod2-/-, untreated
    GSE150498 (wildtype, 1X DSS) intestine disease 6dpf, wildtype, 1X DSS Enteroendocrine (cluster: 6)
    potential marker
    NA
    GSE150498 (nod2-|-, 1X DSS) intestine disease 6dpf, nod2-/-, 1X DSS Enteroendocrine (cluster: 5)
    potential marker
    NA
    GSE150498 (wildtype, 2X DSS+BZA) intestine disease 6dpf, wildtype, 2X DSS+BZA Enteroendocrine (cluster: 4)
    potential marker
    NA
    GSE150498 (nod2-|-, 2X DSS+BZA) intestine disease 6dpf, nod2-/-, 2X DSS+BZA
    GSE123241 (wild type) neuromast baseline 5dpf, wild type during sensory hair cell regeneration, lateral line sensory Central support cells (cluster: 2)
    potential marker
    NA
    GSE123241 (fgf3 mutants) neuromast regeneration 5dpf, fgf3 mutants during sensory hair cell regeneration, lateral line sensory Central support cells (cluster: 2)
    potential marker
    NA
    GSE123241 (fgf3 siblings) neuromast regeneration 5dpf, fgf3 siblings during sensory hair cell regeneration, lateral line sensory Central support cells (cluster: 2)
    potential marker
    NA
    PRJNA605021 (hair cells) neuromast baseline 7dpf, posterior lateral-line neuromast cells were isolated from the dissociated trunks of Tg[myo6b:actb1-EGFP] transgenic zebrafish larvae Support cells (cluster: 8)
    potential marker
    NA
    PRJNA415636 (primary pancreatic islet) primary pancreatic islet baseline adult, Zebrabow M, primary pancreatic islet Pancreas endocrine cells (cluster: 1)
    Pancreas endocrine cells (cluster: 2)
    potential marker
    potential marker
    NA
    NA
    GSE122680 (3dpf) retina baseline 3dpf, WT, untreatment Retinal ganglion cells (cluster: 5)
    potential marker
    NA
    GSE122680 (14dpf) retina baseline 14dpf, WT, untreatment Retinal ganglion cells (cluster: 8)
    Horizontal cells (cluster: 9)
    potential marker
    potential marker
    NA
    NA
    GSE122680 (2dpf) retina baseline 2dpf, WT, untreatment Amacrine cells (cluster: 10)
    Retinal ganglion cells (cluster: 8)
    Amacrine cells (cluster: 10)
    Retinal ganglion cells (cluster: 8)
    potential marker
    potential marker
    potential marker
    potential marker
    NA
    NA
    NA
    NA
    PRJNA672101 (nrl-KO) retina growth 5mpf, three retinas from nrl-KO zebrafsih
    PRJNA554650 (6.5dpf) brain baseline 6.5dpf, whole brain of nr1d1:VNP fish
    PRJNA415636 (brain) brain baseline adult, Zebrabow M, brain
    GSE158142 (15dpf) brain, eye baseline 15dpf, untreatment
    GSE158142 (5dpf) brain, eye baseline 5dpf, untreatment
    GSE158142 (8dpf) brain, eye baseline 8dpf, untreatment
    PRJNA610520 (4.5dpf) caudal hematopoietic tissue baseline 4.5dpf, the mixture of same amount of kdrl:mCherry+ cells, CD41:GFP+ cells and double negative cells.
    GSE144944 (fgfr3 +|+) cranial vault baseline 1mpf, fgfr3 +/+
    PRJNA564810 (1dpf) embryo baseline 1dpf, a single-cell transcriptome atlas for zebrafish development
    PRJNA734348 (dome, control) embryo baseline 4.3hpf, dome, oocyte microinjection with Rhodamine B and control MO at oogenesis III stage (GV)
    PRJNA706197 (18hpf) embryo baseline 18hpf, FACS sorted sox10:nEOS cells
    PRJNA706197 (20hpf) embryo baseline 20hpf, FACS sorted sox10:nEOS cells
    GSE126647 (Pbx4-depleted) embryo growth 1.17dpf, Pbx4-depleted nkx2.5:ZsYellow+ cells
    PRJNA564810 (5dpf) embryo baseline 5dpf, a single-cell transcriptome atlas for zebrafish development
    GSE106587 (MZoep mutant) embryo baseline 12hpf, 6 somites, maternal zygotic oep tz57 mutant embryo
    PRJNA706197 (24hpf) embryo baseline 24hpf, FACS sorted sox10:nEOS cells
    GSE173972 (WT, ezh1+|+) embryo baseline 1.25dpf, Kdrl-positive embryos
    PRJNA640816 (2dpf) embryo baseline 2dpf, FACS isolated -4.9sox10:EGFP+ cells
    GSE168695 (5dpf) embryo baseline 5dpf, GFP+ cells isolated from 5 dpf cldnb:lyn-EGFP embryos
    PRJNA706197 (1.25dpf) embryo baseline 1.25dpf, FACS sorted sox10:nEOS cells
    PRJNA706197 (14hpf) embryo baseline 14hpf, FACS sorted sox10:nEOS cells
    PRJNA640816 (2.9dpf) embryo baseline 2.9dpf, FACS isolated -4.9sox10:EGFP+ cells
    GSE158142 (3dpf) head baseline 3dpf, untreatment
    GSE158142 (24hpf) head baseline 24hpf, untreatment
    GSE158142 (2dpf) head baseline 2dpf, untreatment
    GSE158142 (20hpf) head baseline 20hpf, 21-22 somites, untreatment
    PRJNA754013 (zebrafish) hypothalamus baseline adult, male, female, untreatment
    GSE150498 (untreated ctrl) intestine baseline 6dpf, untreated ctrl
    GSE150498 (nod2-|-, 2X DSS) intestine disease 6dpf, nod2-/-, 2X DSS
    GSE150498 (wildtype, untreated) intestine baseline 6dpf, wildtype, untreated
    GSE150498 (wildtype, 2X DSS) intestine disease 6dpf, wildtype, 2X DSS
    PRJNA605021 (supporting cells) neuromast baseline 7dpf, posterior lateral-line neuromast cells were isolated from the dissociated trunks of Tg[Et(krt4:EGFP)sqgw57A] transgenic zebrafish larvae
    PRJNA668529 (3d) olfactory rosette disease 3mpf, intranasal 100ng r-Spike 3 days
    GSE122680 (24hpf) retina baseline 24hpf, WT, untreatment
    PRJNA672101 (WT) retina baseline 5mpf, three retinas from WT zebrafsih
    GSE122680 (1.5dpf) retina baseline 1.5dpf, WT, untreatment
    PRJNA551501 (2mpf) thyroid gland baseline 2mpf, Tg(tg:mVenus-T2A-NTR)
    GSE152982 (wild type) trunk baseline 1.25dpf, untreatment
    GSE163907 (24hpf) trunk baseline 24hpf, trunk tg(sox10:GFP) positive cells
    GSE131136 (all) trunk, skin baseline 5dpf, sox10:CRE positive cells from 5dpf and post-embryonic zebrafish trunks with and without thyroid hormone
    GSE158099 (runx1 -|-) whole body hematopoietic 6dpf, cd41:GFPlow-runx1-/-
    GSE158099 (WT) whole body baseline 16dpf, cd41:GFPlow-WT
    GSE158099 (WT) whole body baseline 2.5dpf, cd41:GFPlow-WT
    GSE176129 (pdgfrb-positive) whole body baseline 5dpf, FACS-isolated pdgfrb-positive cells
    GSE158099 (runx1 -|-) whole body hematopoietic 16dpf, cd41:GFPlow-runx1-/-
    GSE158099 (runx1 -|-) whole body hematopoietic 2.5dpf, cd41:GFPlow-runx1-/-
    GSE158099 (runx1 -|-) whole body hematopoietic 16dpf, cd41:GFPlow-runx1-/-

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