mthfd1l (mthfd1l,si:ch211-266i18.6,LOC107721348,LOC107659212,LOC107665399)


Basic Information

Item Value
gene id mthfd1l
gene name mthfd1l,si:ch211-266i18.6,LOC107721348,LOC107659212,LOC107665399
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047613.1
NCBI id CM018559.1
chromosome length 22090854
location 17608591 ~ 17666128 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026923693.2
gttccggcgtgtgtgtgtgtgttccggtgtgtgtgtgtgcgtgtgtgtgcgcgcgctctCTCTCGACTGCTCCCTCCATAACCGGTGAGCTCTCTTTGTTGGACATCATGAAACTCTCCCCGGTTTTCCGCCGCGCGTGCTCACGAGCCGTGCCTCCACAGAGAGGGTTCATCCCCCGGAGCAGCTCGGTACCGGGGAACAGGACGGGGTTCTGGTTGGCGGTTCGGCACGCGGCGTCCAGCAGCATCGGCGGTACCGGAGCCTCGGAACTTTCACCGGCTCTCAGCTTTCACACACCGCGCGAGACAACCGGCGGCGGGTCCGCGAGAGAAAACATCAGCCGGGAGATCATCCAGAGGAGCAGAGAGGAGCTCGCTGCCGTAGTGAAAACACACGCAGGTATCAAACCCACCCTGGCCATCATACAGgcaGGTGAAGATGACGCTTTACTGGACATCAATAAGAAGATGGCGGGAAAGGTCGGACTGAATGTGATGCAGATCTGTCTGCCGAGCCACTGCACACaggaggagGTCACGGAGGAGGTGCTGAGGCTGAACGAAGATCCGAACGTTCATGGTGTGTTCCTGTGTCTTCCTCCTTCGCTCCTCTCCCGCAGAGTGCTCAACTCCATCAAACCTGAGAAAGATGTGGACGGggtttCAGACCTGAATGTGGGCCGTCTGGTGTCAGGAGCTCTGTCTGAAGGCTTTCTCTCTCCTGTAATAGGAGCAGTGCTGGAGCTGCTGGCCAGACACGATGCTCCTCTGGCTGGGAAGAAGGCGGTGCTGGTGGGACTGAACGGGCCGCTGAACGCGATCCTCCAGCATCTGCTGCAGAACGAGGGTGTGGAGGTGCAGACGAGCCACTGGAGCTCAGACAGGCTGCAGAAACAGGTGAAGCAGGCTGATGTGGTTGTAGTGATGGGAGCCGATTACACGACACTCCCAAACACGTGCTTCAAACCTGGAGTGACTCCCATTAACTGTGGCCCTGCATTAACACCAGCGTTCTCAGCTCATGGGAAGAAGCTGGAGGCTGAATCCTGGCCGGATGTTGGACCCATAAGTGCAGCTCTCAGGATGCAGAACGTGGTGAGGAGCAGCAGGAGGTGGGTGGAAGGACAGCAGTATCAGCCTTGGACGCTCTGCCCCCTGAAGCTCCAGCCTCTGTGTCCTGTGCCCAGTGACATAGAGATCTCCCGAGCTCAGACTCCGAAGCCCATAGTGCAGCTGGCGGAGGAAATCGGCTTGTTGCCGGAGGAGCTGGAGGCGTACGGCCGCTCCAAAGCCAAGGTTCAGCTCTCAGTACTCAAACGCCTGCAGCAGCAACCTAACGGCAAATATGTCCTCGTGGCAGGcaTCACTCCGACTCCTCTAGGTGAAGGGAAGAGCACAGTGACGATCGGTCTGGTCCAGGCTCTCTCGGCTCATCTCAAACTCAACTCCTTCGCCTGCCTCAGACAGCCGTCTCAGGGTCCTACATTCGgagttaaagGTGGAGCAGCAGGTGGAGGATATGCTCAGGTCATCCCTATGGAGGAGTTTAATCTCCACTTGACCGGTGACATTCACGCCATAACAGCAGCGAATAACCTGGTGGCAGCAGCCATCGATGCCCGAATCCTGCACGAAGCCACCCAGTCTGATAAGgcccTGTATAACAGACTCGTACCGTCAGTTAATGGAGTGAGACGCTTCTCTGCCATCCAGCTGGGGCGACTGAAGCGACTTGGAATCAACAAATCCGACCCCAACACCCTCACACCTGAGGAGGTCAATGCCTTCGTTCGGCTCGACCTTGACCCTGCGAAGGTCACTTGGCAGAGAGTGGTGGACACCAACGATCGTTTCCTGAGGAAGATCACGGTCGGCCAGGCGAACACGGAGAAAGGCCACAGCCGGCAGactcAGTTTGATATCGCGGTGGCGAGTGAGATCATGGCGATTCTGGCTCTGACTGACGGTCTGGCTGATATGAAGAGCCGTCTGGGCCGCATGGTGGTGGGCAGCAGCAGGAGCGGGCAGCCAGTAACAGCTGATGATCTCGGTGTAACTGGAGCTCTGGCTGTTCTGATGAAAGATGCCATCAAACCCACCCTGATGCAGACGCTCGAGGGAACGCCGGTGTTTGTGCATGCCGGACCGTTCGCCAACATCGCCCACGGAAACTCGTCAGTGCTGGCGGACCAACTGGCTCTCAAACTGGTCGGAGAGGACGGCTATGTGGtgacgGAGGCAGGTTTCGGAGCAGACATCGGCATGGAGAAGTTCTTCAACATTAAATGCCGTGCCTCCGGACTGAAGCCTGACGTCGTGGTGTTGGTCGCCACCATCAGGGCTCTGAAGATGCACGGAGGAGGTCCGAATGTAACAGCAGGAGTGCCTCTCCCAAAAGAATACACTGAGGAGAATCTAAAATTGGTCTCCGAAGGTTGCAGCAATCTGAAGAAACAGATCCAGATCGCGCGTCTGTTTGGAGTTCCCGTGGTGGTGGCTCTCAACACCTTTAAGACTGACACGGAGGCCGAGATGGAGCTGGTGTGTCGTATAGCTGAGGCTTCAGGGGCATCAGCGGCCTTGCCGTGTCATCACTGGGGGCGGGGCGGACGCGGCGCCATGGAGCTGGCACACGCCGTGAAGGAAGCGGCAGCACAGAAGAGCGATTTCCACTTCCTGTACAGCCTTCAGACCCCCATCGTGGAGAAAATCCGCACTATCGCACAGAAGGTTTATGGAGCTGATGACATCGAGTTATCATCTGAAGCACAAGCTAAAATTGACTATTACACACAACAGGGCTTTGACACTCTACCCATATGCATGGCCAAAacccacctgtctctctctcacatgcctGAGAAAAAGGGCGTGCCCACTGGCTTCATCCTGCCAATCAGAGACGTCCGTGCCAGCATAGGGGCGGGGTTTATTTATCCACTGGTTGGAACAATGAGCACCATGCCAGGTCTTCCTACACGACCCTGTTTCTATGACATCGATCTTGACCCCATAACCGAGGAGATATCGGGGCTCTTTTAAcaatccacacactcacacacacactctcaacagCTGTGTCAGGTTGATGGTGATGGTTCGAGTGACCTGGAGCAAACGTACCCTGTCTTTAGGGCTAACAGAGGACCAAATGTTCCTTCAGATGCATCTGCACAtcatctgtaatttttttaatgcattatttacaAGTTTCATTATACAGAGATTGCAAAGACACGGAGAACtctagtttctttttttttaatcctgttttcTTTTAGAAACTAATTTCATGCTTAGATTTCACACTTCAATGCAGTTACTTTTTTCCGggtttatcatttttacacctttttatttttcatccttttttaatgcattatttacaAGAATTTGTTTGAAGAGAGATTGCAAAGAATTTCAGACAGGGAAATCTCTCTGCAATCTTGGTTGCAGTTCTTTAGTTTAGAAACTAAAATCGAGTTGAGTTCAGATTTCACCCTCGAATGAGGTTTATTTGACCAGGTTTTGTGTTTGGCCAGATTTTATGGctttggggagaaaaagaaCTTGAGTTCCTGTCTGAATGTAATCTAAGCTGGTTTTGGATtggttacatttcattttttattcagcctttacatttatttatttataattctgATGTACACTCTACAGCTTCTAACACTGCTGTCATTCCGCAACTGCTGTCATTACGTCTGTGCCAGGACATGCTTTTGCATGTCTTGTAATAAATTTCCAATAATCAGTT

Function

symbol description
si:ch211-266i18.6 Predicted to enable ATP binding activity; formate-tetrahydrofolate ligase activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to act upstream of or within one-carbon metabolic process.
mthfd1l Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to act upstream of or within one-carbon metabolic process. Predicted to be active in cytosol. Is expressed in anterior neural tube and optic cup. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like).

NR:

description
monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X2

GO:

id name namespace
GO:0009396 folic acid-containing compound biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004329 formate-tetrahydrofolate ligase activity molecular_function

KEGG:

id description
K13402 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026923693.2 True 3771 mRNA 0.53 28 17608591 17666128

Neighbor

gene id symbol gene type direction distance location
akap12b akap12 coding downstream 7831 17538910 ~ 17600760 (-)
armt1 armt1 coding downstream 87880 17512447 ~ 17520711 (-)
myct1a myct1 coding downstream 348725 17256381 ~ 17259866 (-)
serac1 serac1,LOC107555766 coding downstream 359670 17237824 ~ 17248921 (-)
si:dkey-12h9.6 LOC108258171,LOC103045157,LOC108424494,LOC105908978 coding downstream 376493 17216213 ~ 17232098 (-)
gpr176 gpr176,LOC102785786 coding upstream 17869 17683997 ~ 17699560 (-)
LOC113532304 LOC108257600 coding upstream 94491 17760619 ~ 17767511 (-)
LOC113531908 NA coding upstream 102416 17768544 ~ 17775954 (-)
fntb fntb,LOC108257588,LOC108424508,LOC107756604,LOC107668263,LOC107721314,LOC107671778,LOC106571088,LOC105024336 coding upstream 142170 17808298 ~ 17825400 (-)
zfyve1 zfyve1,LOC107721321 coding upstream 450422 18116550 ~ 18130493 (-)
G297442 NA non-coding downstream 125704 17482324 ~ 17482887 (-)
LOC113531886 NA non-coding downstream 187139 17415966 ~ 17421452 (-)
G297053 NA non-coding downstream 526477 17081872 ~ 17082114 (-)
G297052 NA non-coding downstream 542163 17065682 ~ 17066428 (-)
G297050 NA non-coding downstream 544206 17064166 ~ 17064385 (-)
G297670 NA non-coding upstream 39472 17705600 ~ 17760410 (-)
G297712 NA non-coding upstream 175433 17841561 ~ 17842853 (-)
G297718 NA non-coding upstream 188757 17854885 ~ 17953471 (-)
G297720 NA non-coding upstream 199160 17865288 ~ 17865651 (-)
G297724 NA non-coding upstream 208324 17874452 ~ 17874744 (-)
esr1 esr1 other downstream 101933 17485584 ~ 17506658 (-)
gtf2h5 gtf2h5,tf2h5,LOC107721375,LOC107659223 other downstream 372462 17233977 ~ 17236129 (-)
ttc32 ttc32 other downstream 561760 17043166 ~ 17046831 (-)
G296802 igf2r other downstream 1050664 16555103 ~ 16557927 (-)
pln NA other downstream 1465975 16134134 ~ 16142616 (-)
acot20 LOC108257587,LOC108257591 other upstream 41158 17707286 ~ 17715272 (-)
dpf3 dpf3,LOC108257599,LOC108424513,LOC107659173,LOC107721322,LOC107668213,LOC107562702,LOC107602065,LOC107756570 other upstream 406417 18072545 ~ 18105993 (-)
ubr7 LOC108257828,LOC108411326 other upstream 1404332 19070460 ~ 19083511 (-)
LOC113525604 LOC108258223 other upstream 1708645 19374773 ~ 19410374 (-)
LOC113524711 NA other upstream 1763063 19429191 ~ 19451604 (-)

Expression


Co-expression Network